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Principles and Biophysics of Dialysis

  • Chapter
Replacement of Renal Function by Dialysis

Abstract

Intermittent dialysis therapy is used in chronic uremia to re-establish body water solute concentrations that cannot be achieved by the natural organ. In this sense, the dialyzer becomes an artificial kidney and it is through the transport of substances by this device that chemical and biophysical control consistent with continued survival is achieved. This chapter is organized as shown in Figure 1 and consists of two basic lines of development:

  1. 1.

    Consideration of the dialyzer and its operating principles.

  2. 2.

    Application of mass balance priciples to various solute systems and the effect of dialyzer use on solute control during intermittent dialysis theraphy.

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Authors
  1. John A. Sargent
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  2. Frank A. Gotch
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Editors and Affiliations

  1. Nephrology Division, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

    John F. Maher M.D., FACP (Professor of Medicine, Director) (Professor of Medicine, Director)

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© 1989 Kluwer Academic Publishers

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Sargent, J.A., Gotch, F.A. (1989). Principles and Biophysics of Dialysis. In: Maher, J.F. (eds) Replacement of Renal Function by Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1087-4_4

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  • DOI: https://doi.org/10.1007/978-94-009-1087-4_4

  • Publisher Name: Springer, Dordrecht

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