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The critical ATP threshold hypothesis

  • Chapter
Pathophysiology of Severe Ischemic Myocardial Injury

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 104))

Abstract

Despite the discussions in other sections of this book on the final causes of cell death, this chapter will analyse whether any correlation exists during ischemia between the cellular energetic situation and disturbances of functions, metabolism and structure of myocardial cells. In this context, the question arises as to whether a critical cellular ATP level marks the transgression from a living to a dead cell, marking a ‘point of no return’.

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Author information

Authors and Affiliations

  1. Institute of Medical Physiology, University of Vienna, A-1090, Schwarzspanierstraβe 17, Austria

    P. G. Spieckermann

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  1. P. G. Spieckermann
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Editors and Affiliations

  1. Institute of Physiology, University of Düsseldorf, Düsseldorf, Germany

    Hans Michael Piper

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© 1990 Kluwer Academic Publishers

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Spieckermann, P.G. (1990). The critical ATP threshold hypothesis. In: Piper, H.M. (eds) Pathophysiology of Severe Ischemic Myocardial Injury. Developments in Cardiovascular Medicine, vol 104. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0475-0_3

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  • DOI: https://doi.org/10.1007/978-94-009-0475-0_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-0459-3

  • Online ISBN: 978-94-009-0475-0

  • eBook Packages: Springer Book Archive

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