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Irreversible ischemic injury — definition of the problem

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Pathophysiology of Severe Ischemic Myocardial Injury

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 104))

Abstract

In spite of tremendous strides forward in cardiac pathophysiology over the past 30 years, knowledge of the genesis of irreversible ischemic myocardial injury is still limited. Ischemic myocardial heart disease is predominantly caused by the thrombotic occlusion of coronary arteries. After an initial period of ischemia during which restoration of supply conditions still allows structural and functional recovery of the myocardial cell, ischemic injury becomes irreversible or, in other words, reversible ischemia turns into infarction.

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Authors and Affiliations

  1. Institut für Physiologie I, Universität Düsseldorf, Moorenstr. 5, D-4000, Düsseldorf, Germany

    Hans Michael Piper

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  1. Hans Michael Piper
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  1. Institute of Physiology, University of Düsseldorf, Düsseldorf, Germany

    Hans Michael Piper

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© 1990 Kluwer Academic Publishers

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Piper, H.M. (1990). Irreversible ischemic injury — definition of the problem. In: Piper, H.M. (eds) Pathophysiology of Severe Ischemic Myocardial Injury. Developments in Cardiovascular Medicine, vol 104. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0475-0_1

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  • DOI: https://doi.org/10.1007/978-94-009-0475-0_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-0459-3

  • Online ISBN: 978-94-009-0475-0

  • eBook Packages: Springer Book Archive

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