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The Versatility of Peroxisome Function in Filamentous Fungi

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Peroxisomes and their Key Role in Cellular Signaling and Metabolism

Part of the book series: Subcellular Biochemistry ((SCBI,volume 69))

Abstract

Peroxisomes are ubiquitous and versatile cell organelles. They consist of a single membrane that encloses a proteinaceous matrix. Conserved functions are fatty acid β-oxidation and hydrogen peroxide metabolism. In filamentous fungi, many other metabolic functions have been identified. Also, they contain highly specialized peroxisome-derived structures termed Woronin bodies, which have a structural function in plugging septal pores in order to prevent cytoplasmic bleeding of damaged hyphae.

In filamentous fungi peroxisomes play key roles in the production of a range of secondary metabolites such as antibiotics. Most likely the atlas of fungalperoxisomal metabolic pathways is still far from complete. Relative recently discovered functions include their role in biotin biosynthesis as well as in the production of several toxins, among which polyketides. Finally, in filamentous fungi peroxisomes are important for development and pathogenesis.

In this contribution we present an overview of our current knowledge on fungal peroxisome formation as well as on their functional diversity.

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Acknowledgments

We are grateful to Rinse de Boer for preparing the electron micrographs of Fig. 8.3 and preparing all figures.

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Authors and Affiliations

  1. Molecular Cell Biology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, 11103, 9700CC, Groningen, The Netherlands

    Ida J. van der Klei & Marten Veenhuis

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  1. Ida J. van der Klei
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  2. Marten Veenhuis
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Correspondence to Ida J. van der Klei .

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  1. , Depto. Bioquímica, Biología Celular y, Estación Experimental del Zaidín, CSIC, Profesor Albareda 1, Granada, 18008, Spain

    Luis A. del Río

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van der Klei, I.J., Veenhuis, M. (2013). The Versatility of Peroxisome Function in Filamentous Fungi. In: del Río, L. (eds) Peroxisomes and their Key Role in Cellular Signaling and Metabolism. Subcellular Biochemistry, vol 69. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6889-5_8

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