Abstract
Recent scientific research has focused on food components that have possible health benefits beyond traditional nutritional value. Nutraceuticals as an amalgamation of the terms nutritional and pharmaceutical refers to foods or parts of foods that provide medical or health benefits, including the prevention and/or treatment of disease. There is growing recognition of the potential role for nutraceuticals in helping to reduce health risks and improve health quality. In the global marketplace nutraceuticals have become a multi-billion dollar industry. Nutraceuticals may range from isolated nutrients, herbal products, dietary supplements and diets to genetically engineered “designer” foods and processed products such as cereals, soups, juices and beverages. Major chemical groups now recognized as having potential health promoting effects are the phenolics, flavonoids, alkaloids, carotenoids, pre- and probiotics, phytosterols, tannins, fatty acids, terpenoids, saponins, and soluble and insoluble dietary fibres. Some examples of relationships between nutraceuticals and health benefits include the importance of calcium in preventing osteoporosis, foliate in the prevention of neural tube defects in infants and the role of decreasing dietary fat and increasing fiber in the prevention of colon cancer. Advances in the areas of food technology, food biochemistry and the nutritional sciences (including nutritional genomics) are providing consumers with access to fresh and often supplemented produce with recognizable health benefits that previously were not available. New methods being used by the functional food industry to isolate, characterize, extract and purify nutraceuticals from microorganisms, plant and animal sources are resulting in decreased costs to the industry as well as providing new options for use of nutraceuticals. The health promoting effects of nutraceuticals likely are due to a complex mix of biochemical and cellular interactions which together promote overall health of the individual. Nutraceuticals may function: as substrates in metabolic reactions or cofactors of key metabolic enzymes; as ligands that promote or compete with biochemical interactions at the cell surface or with intercellular receptors which can enhance absorption and assimilation of important macro- and micronutrients; and as agents which selectively promote the growth of bacteria (especially lactic acid bacteria) with health benefits in the gastrointestinal system and compete with or partially eliminate the growth of harmful bacteria. In addition these agents may act as enzyme inhibitors, absorbents or toxicant scavengers that can associate with and help remove damaging substances or toxins from the body. Application of modern approaches in genomics, proteomics and metabolomics to the study of genetics and the biochemistry of functional foods derived from plants and animals has potential to characterize these products in a better way. Moreover, these approaches will enable us to modify product characteristics with precision. Considerable attention now is being paid to characterization of the natural biodiversity found throughout the planet. Plants in particular, present opportunities to alter their biochemical makeup to adapt to new applications and challenges, as well as providing a diverse array of growth responses that can be exploited to allow their use under many different regional ecological conditions. This chapter will provide definition, introduction, worldwide status and classification of nutraceuticals and its significance and nutrigenomics. Further, the regulatory status and recent development in nutraceuticals are discussed.
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References
Afman, L., & Müller, M. (2006). Nutrigenomics: From molecular nutrition to prevention of disease. Journal of the American Dietetic Association, 106, 569–576.
Ali, R., Athar, M., Abdullah, U., Abidi, S. A., & Qayyum, M. (2009). Nutraceuticals as natural healers: Emerging evidences. African Journal of Biotechnology, 8(6), 891–898.
Brower, V. (1998). Nutraceuticals: Poised for a healthy slice of the healthcare market? Nature Biotechnology, 16, 728–731.
Camire, M. E. (2003). Nutraceuticals for health promotion and disease prevention (Issue Paper 24). Ames: Council for Agricultural Science and Technology.
Datta, B. S., & Basu, S. K. (2002). Environmental perspectives and human responses. National Service Scheme 2000–01: Government of India. Kolkata: S. Graphics.
Desiere, F. (2004). Towards a systems biology understanding of human health: Interplay between genotype, environment and nutrition. Biotechnology Annual Review, 10, 51–84.
Dhami, V. P. S., & Chopra, K. (2000). The world of nutraceuticals. The Eastern Pharmacist, 29–30.
Dunn, W. B., Bailey, N. J., & Johnson, H. E. (2005). Measuring the metabolome: Current analytical technologies. Analyst, 130, 606–625.
Food and Agriculture Organization of the United Nations (FAO). (2007). Report on functional foods, food quality and standards service (AGNS). Rome: FAO.
Functional Food Japan. (2006). Project Report. Japan.
German, J. B., Roberts, M. A., & Watkins, S. M. (2003). Genomics and metabolomics as markers for the interaction of diet and health: Lessons from lipids. Journal of Nutrition, 133(1), 2078–2083.
Gupta, S., Chauhan, D., Mehla, K., Sood, P., & Nair, A. (2010). An overview of nutraceuticals: Current scenario. Journal of Basic and Clinical Pharmacy, 1(2), 55–62.
Halsted, C. H. (2003). Dietary supplements and functional foods: 2 sides of a coin? American Journal of Clinical Nutrition, 77, 1001–1007.
Hobbs, J. E. (2002). Evolving supply chains in the nutraceuticals and functional food industry. Canadian Journal of Agricultural Economics, 50(4), 559–568.
Just-food. (2007). Global market review of functional foods – forecasts to 2012. Arog. Limited, http://www.just-food.com/store/product.aspx?id=44028and1k=pop
Kalra, E. K. (2003). Nutraceutical–definition and introduction. AAPS PharmSci, 5(2), E25.
Keservani, R. K., Kesharwani, R. K., Vyas, N., Jain, S., Raghuvanshi, R., & Sharma, A. K. (2010). Nutraceutical and functional food as future food: A review. Der Pharmacia Lettre, 2(1), 106–116.
Koletzko, B., Aggett, P. J., & Bindels, J. G. (1998). Growth, development and differentiation: A functional food science approach. British Journal of Nutrition, 80, 5–45.
Laparra, J. M., & Sanz, Y. (2010). Interactions of gut microbiota with functional food components and nutraceuticals. Pharmacological Research, 61(3), 219–225.
Laroche, A. (2007). Biotechnology and medicinal plants. In S. N. Acharya & J. E. Thomas (Eds.), Advances in medicinal plant research (p. 339). Kerala: Research Signpost.
Mani, T. T., Mukherjee, P. K., Manimaran, S., & Suresh, B. (2002). Indian herbal drug development – problems and prospects. Pharma Times, 34, 13–14.
Ohama, H., Ikeda, H., & Moriyama, H. (2006). Health foods and foods with health claims in Japan. Toxicology, 221, 95–111.
Patwardhan, B. D., Warude, P. P., & Bhatt, N. (2005). Ayurveda and traditional Chinese medicine: A comparative overview. Evidence-Based Complementary and Alternative Medicine, 2(4), 465–473.
Rajasekaran, A., Sivagnanam, G., & Xavier, R. (2008). Nutraceuticals as therapeutic agents: A review. Research Journal of Pharmacy and Technology, 1(4), 28–40.
Rishi, R. K. (2006). Nutraceuticals: Borderline between food and drug?. The Pharma Review, 51–53.
Ross, S. (2000). Functional foods: The food and drug administration perspective. American Journal of Clinical Nutrition, 71, 1735–1738.
Singh, J., Singh, A. K., & Khanuja, S. P. S. (2003). Medicinal plants: India’s opportunities. Pharma Bioworld, 1, 59–66.
Tata Strategic Management Group. (2009). The Health and Wellness Foods Industry in India: An overview. Osaka International Business Promotion Center, Mumbai 400013, India.
Verma, S. (2009). An empirical analysis of consumer’s attitude towards OTC health supplements in India. International Journal of Indian Culture and Business Management, 2(1), 1–10.
Whitman, M. (2001). Understanding the perceived need for complementary and alternative nutraceuticals: Lifestyle issues. Clinical Journal of Oncology Nursing, 5, 190–194.
Zhao, J. (2007). Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: A perspective on plant biotechnology application. Recent Patents on Biotechnology, 1, 75–97.
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The authors are very thankful to Dr. Dinesh Aggarwal, Director, UIET, Kurukshetra University, Kurukshetra and Director and Management, ACE, Mithapur, Ambala for encouraging us to write this chapter.
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Jain, P., Pundir, R.K. (2013). Nutraceuticals: Recent Developments and Future Prospectives. In: Shahid, M., Shahzad, A., Malik, A., Sahai, A. (eds) Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6603-7_9
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