Skip to main content

Image Based Model Development and Analysis of the Human Knee Joint

  • Chapter
  • First Online:
Biomedical Imaging and Computational Modeling in Biomechanics

Part of the book series: Lecture Notes in Computational Vision and Biomechanics ((LNCVB,volume 4))

Abstract

Developments in medical imaging and finite element analysis techniques have made it possible to conduct personalized studies on patients. The field of medical implants is especially benefitting from these advancements, where patient specific geometries can be created and analyzed. The present work is focused on using image based techniques for construction of solid models of human knee joints for finite element analysis. Accurate 3D solid models of the human cadaveric knee joint are developed based on a sequence of high resolution MRI images obtained from a Siemens 7T machine. The approach involves identification of various components of the knee joint such as the femur, tibia, femoral and tibial cartilage, and menisci of the tibio-femoral knee joint; construction of a 3D model; smoothing the geometries; meshing of geometry; and then performing finite element analysis. The focus of the present work is on understanding the effect of menisci on the stress and strain distribution in the knee joint. Availability of such image based modeling and analysis methods would help in designing effective meniscal implants.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Alatakis S, Naidoo P (2009) MR imaging of meniscal and cartilage injuries of the knee. Magn Reson Imaging Clin North Am 17:741–756

    Article  Google Scholar 

  • Arokoski JPA et al (2000) Normal and pathological adaptations of articular cartilage to joint loading. Scand J Med Sci Sports 10:186–198

    Article  Google Scholar 

  • Baldwin MA et al (2009) Efficient probabilistic representation of tibiofemoral soft tissue constraint. Comput Methods Biomech Biomed Engin 12:651–659

    Article  Google Scholar 

  • Baldwin MA et al (2010) Development of subject-specific and statistical shape models of the knee using an efficient segmentation and mesh-morphing approach. Comput Methods Programs Biomed 97:232–240

    Article  Google Scholar 

  • Bendjaballah MZ, Shirazi-Adl A, Zukor DJ (1995) Biomechanics of the human knee joint in compression: reconstruction, mesh generation and finite element analysis. Knee 2:69–79

    Article  Google Scholar 

  • Bendjaballah MZ, Shirazi-Adl A, Zukor DJ (1997) Finite element analysis of human knee joint in varus-valgus. Clin Biomech 12:139–148

    Article  Google Scholar 

  • Blankevoort L et al (1991) Articular contact in a three-dimensional model of the knee. J Biomech 24:1019–1031

    Article  Google Scholar 

  • Busse H et al (2008) In vivo glenohumeral analysis using 3D MRI models and a flexible software tool: feasibility and precision. J Magn Reson Imaging 27:162–170

    Article  Google Scholar 

  • Chang G et al (2010) Biochemical and physiological MR imaging of skeletal muscle at 7 tesla and above. Semin Musculoskelet Radiol 14:269–278

    Article  Google Scholar 

  • Chaudhary ME, John D, Walker PS (2011) Relative stability provided by the medial meniscus and cruciate ligaments at high and low axial compressions. In: ASME summer bioengineering conference, Farmington, PA, USA, 22–25 June

    Google Scholar 

  • Cheng YJ et al (2010a) Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation-United States, 2007–2009. JAMA 304:2238–2239

    Google Scholar 

  • Cheng YY et al (2010b) 3D FEA of high-performance polyethylene fiber reinforced maxillary dentures. Dent Mater 26:e211–e219

    Article  Google Scholar 

  • Cohen ZA et al (1999) Knee cartilage topography, thickness, and contact areas from MRI: in-vitro calibration and in-vivo measurements. Osteoarthritis Cartilage 7:95–109

    Article  Google Scholar 

  • DeFrate LE et al (2004) In vivo tibiofemoral contact analysis using 3D MRI-based knee models. J Biomech 37:1499–1504

    Article  Google Scholar 

  • Englund M (2008) The role of the meniscus in osteoarthritis genesis. Rheum Dis Clin North Am 34:573–579

    Article  Google Scholar 

  • Englund M, Guermazi A, Lohmander LS (2009) The meniscus in knee osteoarthritis. Rheum Dis Clin North Am 35:579–590

    Article  Google Scholar 

  • Fan W et al (2008) Identification of a C-shaped canal system in mandibular second molars–Part III: anatomic features revealed by digital subtraction radiography. J Endod 34:1187–1190

    Article  Google Scholar 

  • Ferraz EG et al (2011) Effect of different surface processing protocols in three-dimensional images for rapid prototyping. Adv Eng Softw 142:332–335

    Article  Google Scholar 

  • Garstang SV, Stitik TP (2006) Osteoarthritis: epidemiology, risk factors, and pathophysiology. Am J Phys Med Rehabil 85:S2–S11

    Article  Google Scholar 

  • Gíslason MK, Stansfield B, Nash DH (2010) Finite element model creation and stability considerations of complex biological articulation: the human wrist joint. Med Eng Phys 32:523–531

    Article  Google Scholar 

  • Guo Y, Zhang X, Chen W (2009) Three-dimensional finite element simulation of total knee joint in gait cycle. Acta Mech Solida Sin 22:347–351

    Google Scholar 

  • Hao Z et al (2007) A finite element 3D model of in vivo human knee joint based on MRI for the tibiofemoral joint contact analysis. In: 1st international conference on digital human modeling, Beijing, China, Springer, Berlin/Heidelberg, LNCS, vol 4561, pp 616–622

    Google Scholar 

  • Haut Donahue TL et al (2002) A finite element model of the human knee joint for the study of tibio-femoral contact. J Biomech Eng 124:273–280

    Article  Google Scholar 

  • Haut Donahue TL et al (2003) How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. J Biomech 36:19–34

    Article  Google Scholar 

  • Hootman JM, Helmick CG (2006) Projections of US prevalence of arthritis and associated activity limitations. Arthritis Rheum 54:226–229

    Article  Google Scholar 

  • Liu P (2011) Construction of 3D finite element model of upper end of tibia. In: 3rd international conference on measuring technology and mechatronics automation, Shanghai, 6–7 Jan, pp 766–769

    Google Scholar 

  • Loeser RF, Shakoor N (2003) Aging or osteoarthritis: which is the problem? Rheum Dis Clin North Am 29:653–673

    Article  Google Scholar 

  • Madelin G et al (2010) Sodium inversion recovery MRI of the knee joint in vivo at 7T. J Magn Reson 207:42–52

    Article  Google Scholar 

  • Magne P (2007) Efficient 3D finite element analysis of dental restorative procedures using micro-CT data. Dent Mater 23:539–548

    Article  Google Scholar 

  • Ni Y et al (2008) Quantitative morphology of facial nerve based on three-dimensional reconstruction of temporal bone. Otolaryngol Head Neck Surg 138:23–29

    Article  Google Scholar 

  • Pakin SK et al (2006) Ultra-high-field MRI of knee joint at 7.0T: preliminary experience. Acad Radiol 13:1135–1142

    Article  Google Scholar 

  • Peña E et al (2005) Finite element analysis of the effect of meniscal tears and meniscectomies on human knee biomechanics. Clin Biomech 20:498–507

    Article  Google Scholar 

  • Peña E et al (2006) Why lateral meniscectomy is more dangerous than medial meniscectomy. A finite element study. J Orthop Res 24:1001–1010

    Article  Google Scholar 

  • Peña E et al (2008) Computer simulation of damage on distal femoral articular cartilage after meniscectomies. Comput Biol Med 38:69–81

    Article  Google Scholar 

  • Périé D, Hobatho MC (1998) In vivo determination of contact areas and pressure of the femorotibial joint using non-linear finite element analysis. Clin Biomech 13:394–402

    Article  Google Scholar 

  • Regatte RR, Schweitzer ME (2007) Ultra-high-field MRI of the musculoskeletal system at 7.0T. J Magn Reson Imaging 25:262–269

    Article  Google Scholar 

  • Regatte RR, Schweitzer ME (2008) Novel contrast mechanisms at 3 tesla and 7 tesla. Semin Musculoskelet Radiol 12:266–280

    Article  Google Scholar 

  • Rho JY et al (2002) Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation. J Biomech 35:189–198

    Article  Google Scholar 

  • Robertson DD et al (2003) Knee joint biomechanics: relevance to imaging. Semin Musculoskelet Radiol 7:43–58

    Article  Google Scholar 

  • Sathasivam S, Walker PS (1997) A computer model with surface friction for the prediction of total knee kinematics. J Biomech 30:177–184

    Article  Google Scholar 

  • Sharma L et al (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286:188–195

    Article  Google Scholar 

  • Shin DS, Lee K, Kim D (2007) Biomechanical study of lumbar spine with dynamic stabilization device using finite element method. Comput Aided Des 39:559–567

    Article  Google Scholar 

  • Shirazi R, Shirazi-Adl A (2009) Analysis of partial meniscectomy and ACL reconstruction in knee joint biomechanics under a combined loading. Clin Biomech 24:755–761

    Article  Google Scholar 

  • Song Y et al (2008) Meniscectomy alters the dynamic deformational behavior and cumulative strain of tibial articular cartilage in knee joints subjected to cyclic loads. Osteoarthritis Cartilage 16:1545–1554

    Article  Google Scholar 

  • Tang S-T et al (2009) Clinical value of pelvic 3-dimensional magnetic resonance image reconstruction in anorectal malformations. J Pediatr Surg 44:2369–2374

    Article  Google Scholar 

  • Trilha M Jr et al (2009) Simulação numérica tridimensional da mecânica do joelho humano. Acta Ortop Bras 17:18–23

    Article  Google Scholar 

  • Vadher SP et al (2006) Finite element modeling following partial meniscectomy: effect of various size of resection. In: 28th annual international conference of the IEEE “Engineering in Medicine and Biology Society”, New York

    Google Scholar 

  • Vaziri A et al (2008) Influence of meniscectomy and meniscus replacement on the stress distribution in human knee joint. Ann Biomed Eng 36:1335–1344

    Article  Google Scholar 

  • Vedi V et al (1999) Meniscal movement: an in-vivo study using dynamic MRI. J Bone Joint Surg Br 81-B:37–41

    Article  Google Scholar 

  • Walker PSA et al (1997) Knee simulating machine for performance evaluation of total knee replacements. J Biomech 30:83–89

    Article  Google Scholar 

  • Walker PS et al (2009) Design features of total knees for achieving normal knee motion characteristics. J Arthroplasty 24:475–483

    Article  Google Scholar 

  • Walker PS et al (2011) Preclinical evaluation method for total knees designed to restore normal knee mechanics. J Arthroplasty 26:152–160

    Article  Google Scholar 

  • Yang NH, Nayeb-Hashemi H, Canavan PK (2007) The effects of tibiofemoral angle and body weight on the stress field in the knee joint. In: International mechanical engineering Congress and exposition, Seattle, WA, USA, 11–15 Nov

    Google Scholar 

  • Yang NH et al (2010) Effect of frontal plane tibiofemoral angle on the stress and strain at the knee cartilage during the stance phase of gait. J Orthop Res 28:1539–1547

    Article  Google Scholar 

  • Zielinska B, Haut Donahue TL (2006) 3D finite element model of meniscectomy: changes in joint contact behavior. J Biomech Eng 128:115–123

    Article  Google Scholar 

Download references

Acknowledgments

Dr. Peter Walker, Miriam Chaudhary, and Sally Arno at the Laboratory for Minimally Invasive Surgery of the Department of Orthopedic Surgery, NYU Hospital for Joint Diseases are acknowledged for the help with specimen preparations and mechanical testing. The authors acknowledge Dr. Ravinder R. Regatte at NYU Langone Medical Center for the help with MRI imaging and technical discussions. Ansys Inc is thanked for providing reduced price academic research licenses. The authors acknowledge the NYU – NYU-Poly joint seed grant and the MAE department at NYU-Poly for the facilities and support provided.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nikhil Gupta .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

John, D., Pinisetty, D., Gupta, N. (2013). Image Based Model Development and Analysis of the Human Knee Joint. In: Andreaus, U., Iacoviello, D. (eds) Biomedical Imaging and Computational Modeling in Biomechanics. Lecture Notes in Computational Vision and Biomechanics, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4270-3_4

Download citation

  • DOI: https://doi.org/10.1007/978-94-007-4270-3_4

  • Published:

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-4269-7

  • Online ISBN: 978-94-007-4270-3

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics