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Rational Design of Insect Control Agents: The PK/PBAN Family as a Study Case

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Biorational Control of Arthropod Pests

Abstract

The success of modern agriculture in developing and maintaining high-yield crops depends strongly on controlling insect pests by means of heavy use of insecticides, and at present organo-synthetic chemical insecticides remain the main weapon in this armory. However, in recent decades, uncontrolled application of chemical insecticides has led to acquisition of resistance by insects, has contaminated the environment with toxic residues that endanger humans and other life forms, and has disrupted the ecological balance in and around cultivated fields. The growing concern regarding the toxic effects of insecticides has led to the implementation of strict regulations in the Western World, and these are being adopted by other countries too. These regulations limit the application of some organo-chemical insecticides and ban continued use of the more toxic ones.

Contribution from the Agricultural Research Organization, the Volcani CenterBet Dagan, Israel 510/08, 2008 series

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Acknowledgements

This research was supported by US-Israel Binational Agricultural Research and Development Fund (BARD) (IS-3356-02). We would like to thank Professor Gilon of the Department of Organic Chemistry at the Hebrew University of Jerusalem, Israel for the design of the photo-affinity ligands and all other linear and backbone cyclic peptides Mrs. Orna Ben-Aziz and Mr. Michael Davidovitch for excellent experimental work and insect rearing. This manuscript forms part of the M.Sc. thesis of Aliza Hariton, a student at the Hebrew University of Jerusalem.

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  1. Department of Entomology, The Volcani Center, Bet Dagan, 50250, Israel

    Miriam Altstein & Aliza Hariton

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  1. Miriam Altstein
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  2. Aliza Hariton
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Correspondence to Miriam Altstein .

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  1. Volcani Center, Agricultural Research Organization, Bet Dagan, 50250, Israel

    Isaac Ishaaya

  2. Agricultural Research Organization, Gilat Research Center, Mobile Post, Negev, 85280, Israel

    A. Rami Horowitz

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Altstein, M., Hariton, A. (2009). Rational Design of Insect Control Agents: The PK/PBAN Family as a Study Case. In: Ishaaya, I., Horowitz, A. (eds) Biorational Control of Arthropod Pests. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2316-2_3

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