Abstract
Adenosine-sensitive syncope has recently been identified as a cause of syncope in some patients affected by unexplained syncope who have an abnormal response to adenosine triphosphate (ATP) test and a negative work-up after complete conventional investigations [1]. Some authors [2–4] have hypothesized that adenosine could be an important modulator in triggering a vasovagal response in susceptible patients. Indeed, the injection of a bolus of adenosine during head-up tilt testing (HUT) has been seen to provoke a vasovagal response in susceptible patients with syncope with a positivity rate comparable to that of isoproterenol [2, 3]. The ATP test has been suggested as a useful tool to identify a subgroup of patients at high risk of severe cardioinhibitory responses of vagal origin [4]. In a recent study [5], we evaluated the possible relationship between adenosine-sensitive syncope and tilt-induced vasovagal syncope. For this purpose, we performed both the ATP and HUT tests in a group of consecutive patients with syncope of uncertain origin, and compared the clinical characteristics of the patients who had a positive response to one or both tests.
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References
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© 2000 Springer-Verlag Italia
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Menozzi, C. et al. (2000). Adenosine-Sensitive Syncope: Does it Really Exist?. In: Raviele, A. (eds) Cardiac Arrhythmias 1999. Springer, Milano. https://doi.org/10.1007/978-88-470-2139-6_57
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DOI: https://doi.org/10.1007/978-88-470-2139-6_57
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2178-5
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