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Designing Future Clinical Trials for Acute Exacerbations of Chronic Bronchitis

  • Chapter
Mechanisms and Management of COPD Exacerbations

Abstract

To some extent, chronic bronchitis can be considered an orphan disease. In fact, most (if not all) of the drugs used in the stable phase of the disease have been initially developed for treating asthma. Similarly, most trials aimed at demonstrating the efficacy of antibiotics in acute exacerbations (AECB) have been modelled on pneumonia studies. Research in both asthma and pneumonia has been the inspiration of subsequent studies in chronic bronchitis in many cases. Furthermore, a specific approach to the disease which takes into account its unique characteristics has seldom been used by researchers.

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Authors and Affiliations

  1. Servei de Pneumologia, Hospital General Vall d’Hebron, Barcelona, Spain

    M. Miravitlles

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  1. M. Miravitlles
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Editors and Affiliations

  1. Institute of Respiratory Diseases, University of Milan, IRCCS Ospedale Maggiore, Milan, Italy

    Luigi Allegra  & Francesco Blasi  & 

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© 2000 Springer-Verlag Italia

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Miravitlles, M. (2000). Designing Future Clinical Trials for Acute Exacerbations of Chronic Bronchitis. In: Allegra, L., Blasi, F. (eds) Mechanisms and Management of COPD Exacerbations. Springer, Milano. https://doi.org/10.1007/978-88-470-2115-0_9

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  • DOI: https://doi.org/10.1007/978-88-470-2115-0_9

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0066-7

  • Online ISBN: 978-88-470-2115-0

  • eBook Packages: Springer Book Archive

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