Skip to main content

Extension of the Hepar II Model to Multiple-Disorder Diagnosis

  • Conference paper
Intelligent Information Systems

Part of the book series: Advances in Soft Computing ((AINSC,volume 4))

Abstract

The Hepar II system is based on a Bayesian network model of a subset of the domain of hepatology in which the structure of the network is elicited from an expert diagnostician and the parameters are learned from a database of medical cases. The model follows the assumption made in the database that each patient case is diagnosed with a single disorder, i.e., disorders are mutually exclusive.

In this paper, we describe an extension of the Hepar II system to multiple-disorder diagnosis. We show that our network transforms readily to a network that can perform multiple-disorder diagnosis with some benefits to the quality of numerical parameters learned from the database. We demonstrate empirically that the diagnostic performance in terms of single-disorder diagnosis improves under this transformation. The new model is more realistic and we expect that it will be of higher value in clinical practice.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bobrowski, L. (1992): Hepar: Computer system for diagnosis support and data analysis. Prace IBIB 31, Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland

    Google Scholar 

  2. Diez, F. J. (1993): Parameter adjustment in Bayes networks. The generalized Noisy-OR gate. In: Proceedings of the 9th Annual Conference on Uncertainty in Artificial Intelligence (UAI-93), Washington, D.C., 99–105

    Google Scholar 

  3. Henrion, M. (1989): Some practical issues in constructing belief networks. In: Kanal, L. N., Levitt, T. S., Lemmer J. F., editors, Uncertainty in Artificial Intelligence 3, Elsevier Science Publishers B.V., North Holland, 161–173

    Google Scholar 

  4. Howard, R. A., Matheson, J. E. (1984): Influence diagrams. In: Howard, R. A., Matheson, J. E., editors, The Principles and Applications of Decision Analysis, Strategic Decisions Group, Menlo Park, CA, 719–762

    Google Scholar 

  5. Moore A. W., Lee M. S. (1994): Efficient algorithms for minimizing cross validation error. In: Proceedings of the 11th International Conference on Machine Learning, Morgan Kaufmann, San Francisco

    Google Scholar 

  6. Oniśko, A., Druzdzel, M. J., Wasyluk H. (1997): Application of Bayesian belief networks to diagnosis of liver disorders. In: Proceedings of the 3rd Conference on Neural Networks and Their Applications, Kule, Poland, 730–736

    Google Scholar 

  7. Oniśko, A., Druzdzel, M. J., Wasyluk H. (1998): A probabilistic causal model for diagnosis of liver disorders. In: Proceedings of the 7th International Symposium on Intelligent Information Systems (IIS-98), Malbork, Poland, 379–387

    Google Scholar 

  8. Oniśko, A., Druzdzel, M. J., Wasyluk H. (1999): A Bayesian network model for diagnosis of liver disorders. In: Proceedings of the 11th Conference on Biocybernetics and Biomedical Engineering, volume 2, Warszawa, Poland, 842-846

    Google Scholar 

  9. Pearl J. (1988): Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference. Morgan Kaufmann Publishers, Inc., San Mateo, CA

    Google Scholar 

  10. Wasyluk, H. (1995): The four year’s experience with HEPAR-computer assisted diagnostic program. In: Proceedings of the 8th World Congress on Medical Informatics (MEDINFO-95), Vancouver, BC, Canada, 1033–1034

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Physica-Verlag Heidelberg

About this paper

Cite this paper

Oniśko, A., Druzdzel, M.J., Wasyluk, H. (2000). Extension of the Hepar II Model to Multiple-Disorder Diagnosis. In: Intelligent Information Systems. Advances in Soft Computing, vol 4. Physica, Heidelberg. https://doi.org/10.1007/978-3-7908-1846-8_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-7908-1846-8_27

  • Publisher Name: Physica, Heidelberg

  • Print ISBN: 978-3-7908-1309-8

  • Online ISBN: 978-3-7908-1846-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics