Abstract
The Hepar II system is based on a Bayesian network model of a subset of the domain of hepatology in which the structure of the network is elicited from an expert diagnostician and the parameters are learned from a database of medical cases. The model follows the assumption made in the database that each patient case is diagnosed with a single disorder, i.e., disorders are mutually exclusive.
In this paper, we describe an extension of the Hepar II system to multiple-disorder diagnosis. We show that our network transforms readily to a network that can perform multiple-disorder diagnosis with some benefits to the quality of numerical parameters learned from the database. We demonstrate empirically that the diagnostic performance in terms of single-disorder diagnosis improves under this transformation. The new model is more realistic and we expect that it will be of higher value in clinical practice.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bobrowski, L. (1992): Hepar: Computer system for diagnosis support and data analysis. Prace IBIB 31, Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland
Diez, F. J. (1993): Parameter adjustment in Bayes networks. The generalized Noisy-OR gate. In: Proceedings of the 9th Annual Conference on Uncertainty in Artificial Intelligence (UAI-93), Washington, D.C., 99–105
Henrion, M. (1989): Some practical issues in constructing belief networks. In: Kanal, L. N., Levitt, T. S., Lemmer J. F., editors, Uncertainty in Artificial Intelligence 3, Elsevier Science Publishers B.V., North Holland, 161–173
Howard, R. A., Matheson, J. E. (1984): Influence diagrams. In: Howard, R. A., Matheson, J. E., editors, The Principles and Applications of Decision Analysis, Strategic Decisions Group, Menlo Park, CA, 719–762
Moore A. W., Lee M. S. (1994): Efficient algorithms for minimizing cross validation error. In: Proceedings of the 11th International Conference on Machine Learning, Morgan Kaufmann, San Francisco
Oniśko, A., Druzdzel, M. J., Wasyluk H. (1997): Application of Bayesian belief networks to diagnosis of liver disorders. In: Proceedings of the 3rd Conference on Neural Networks and Their Applications, Kule, Poland, 730–736
Oniśko, A., Druzdzel, M. J., Wasyluk H. (1998): A probabilistic causal model for diagnosis of liver disorders. In: Proceedings of the 7th International Symposium on Intelligent Information Systems (IIS-98), Malbork, Poland, 379–387
Oniśko, A., Druzdzel, M. J., Wasyluk H. (1999): A Bayesian network model for diagnosis of liver disorders. In: Proceedings of the 11th Conference on Biocybernetics and Biomedical Engineering, volume 2, Warszawa, Poland, 842-846
Pearl J. (1988): Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference. Morgan Kaufmann Publishers, Inc., San Mateo, CA
Wasyluk, H. (1995): The four year’s experience with HEPAR-computer assisted diagnostic program. In: Proceedings of the 8th World Congress on Medical Informatics (MEDINFO-95), Vancouver, BC, Canada, 1033–1034
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2000 Physica-Verlag Heidelberg
About this paper
Cite this paper
Oniśko, A., Druzdzel, M.J., Wasyluk, H. (2000). Extension of the Hepar II Model to Multiple-Disorder Diagnosis. In: Intelligent Information Systems. Advances in Soft Computing, vol 4. Physica, Heidelberg. https://doi.org/10.1007/978-3-7908-1846-8_27
Download citation
DOI: https://doi.org/10.1007/978-3-7908-1846-8_27
Publisher Name: Physica, Heidelberg
Print ISBN: 978-3-7908-1309-8
Online ISBN: 978-3-7908-1846-8
eBook Packages: Springer Book Archive