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Stereotactic Laser Therapy in Cerebral Gliomas

  • Conference paper
Advances in Stereotactic and Functional Neurosurgery 9

Part of the book series: Acta Neurochirurgica Supplementum ((STEREOTACTIC,volume 52))

Summary

The 1.06 μm Nd:YAG laser and a new fiberoptic delivery system, the Interstitial Thermo-Therapy (ITT) laser fibre, allows stereotactic interstitial irradiation of cerebral tumours. In experimental rat brain studies we found typical laser-tissue effects with a central necrosis and a sharply demarcated oedema towards the normal brain. The size of the lesion depended on the energy and exposure time applied.

In a pilot series we treated 5 patients with cerebral gliomas WHO grade II-III in functionally important regions and monitored the therapeutic effects by MR imaging and PET scan. Early postoperative results showed irreversible necrotic changes in the tumour centre and reversible oedematous changes at the tumour margin. Long-term results will show if stereotactic interstitial laser therapy is a useful supplementary method in the treatment of malignant cerebral tumours.

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References

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Heinrich-Heine-University Dusseldorf, Germany

    M. Bettag, F. Ulrich, M. Sabel & J. C. W. Kiwit

  2. Department of Neuropathology, Heinrich-Heine-University Dusseldorf, Germany

    R. Schober

  3. Department of Diagnostic Radiology, Heinrich-Heine-University Dusseldorf, Germany

    G. Fürst

  4. Department of Nuclear Medicine, Heinrich-Heine-University Dusseldorf, Germany

    K. J. Langen

Authors
  1. M. Bettag
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  2. F. Ulrich
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  3. R. Schober
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  4. G. Fürst
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  5. K. J. Langen
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  6. M. Sabel
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  7. J. C. W. Kiwit
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, University of Birmingham, UK

    Edward R. Hitchcock

  2. Istituto Neurologico “C. Besta”, Milano, Italy

    Giovanni Broggi

  3. Servicio de Neurocirugía, Fundación Iménez Díaz, Madrid, Spain

    Juan Burzaco

  4. Dept. de Neurocirurgia, Fundacion “Sixto Obrador”, Madrid, Spain

    J. Martin-Rodriguez

  5. Department of Neurosurgery, Karolinska Sjukhuset, Stockholm, Sweden

    Björn A. Meyerson

  6. Department of Neurosurgery, Medical University of Debrecen, Debrecen, Hungary

    Szabolcs Tóth

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© 1991 Springer-Verlag/Wien

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Bettag, M. et al. (1991). Stereotactic Laser Therapy in Cerebral Gliomas. In: Hitchcock, E.R., Broggi, G., Burzaco, J., Martin-Rodriguez, J., Meyerson, B.A., Tóth, S. (eds) Advances in Stereotactic and Functional Neurosurgery 9. Acta Neurochirurgica Supplementum, vol 52. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9160-6_23

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  • DOI: https://doi.org/10.1007/978-3-7091-9160-6_23

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9162-0

  • Online ISBN: 978-3-7091-9160-6

  • eBook Packages: Springer Book Archive

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