Summary
Eight groups of altogether 25 goats without neutrahzing antibodies against BVD virus, were inoculated either intranasally or in- tranasally and subcutaneously with two different BVD virus isolates during diflferent stages of gestation. In all 18 goats inoculated within the first 78 days of gestation an abortion and foetal death rate of approximately 100% occurred. Only one goat gave birth to a clinically healthy kid. The other seven goats which were inoculated after the 78th day of gestation showed also a high foetal death rate. Only two of them gave birth to clinically healthy kids. Neutralizing antibodies against BVD virus could be detected in blood samples drawn from 14 kids born at normal term including stillborn and non-viable oflfsprings. BVD virus was reisolated from diflferent organs taken from seven foetuses. It was not possible to isolate BVD virus from any of the normal oflfsprings.
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© 1991 Springer-Verlag
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Depner, K., Hübschle, O.J.B., Liess, B. (1991). BVD-virus infection in goats — experimental studies on transplacental transmissibility of the virus and its effect on reproduction. In: Liess, B., Moennig, V., Pohlenz, J., Trautwein, G. (eds) Ruminant Pestivirus Infections. Archives of Virology, vol 3. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9153-8_31
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DOI: https://doi.org/10.1007/978-3-7091-9153-8_31
Publisher Name: Springer, Vienna
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