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BVD-virus infection in goats — experimental studies on transplacental transmissibility of the virus and its effect on reproduction

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Ruminant Pestivirus Infections

Part of the book series: Archives of Virology ((ARCHIVES SUPPL,volume 3))

Summary

Eight groups of altogether 25 goats without neutrahzing antibodies against BVD virus, were inoculated either intranasally or in- tranasally and subcutaneously with two different BVD virus isolates during diflferent stages of gestation. In all 18 goats inoculated within the first 78 days of gestation an abortion and foetal death rate of approximately 100% occurred. Only one goat gave birth to a clinically healthy kid. The other seven goats which were inoculated after the 78th day of gestation showed also a high foetal death rate. Only two of them gave birth to clinically healthy kids. Neutralizing antibodies against BVD virus could be detected in blood samples drawn from 14 kids born at normal term including stillborn and non-viable oflfsprings. BVD virus was reisolated from diflferent organs taken from seven foetuses. It was not possible to isolate BVD virus from any of the normal oflfsprings.

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References

  1. Barlow RM, Rennie JC, Keir WA, Gardiner AC, Vantsis JT (1975) Experiments in border disease: VII. The disease in goats. J Comp Pathol 85: 291–297

    Article  PubMed  CAS  Google Scholar 

  2. Brown CC, Olander HJ, Castro AE, Behymer DE (1989) Prevalence of antibodies in goats in north-eastern Brazil to selected viral and bacterial agents. Trop Anim Health Prod 21: 167–169

    Article  PubMed  CAS  Google Scholar 

  3. Elazhary MASY, Silim A, Dea S (1984) Prevalence of antibodies of bovine respiratory syncytial virus, bovine diarrhoea virus, bovine herpesvirus-1 and bovine parainfluenza- 3 virus in sheep and goats in Quebec. Am J Vet Res 45: 1660–1662

    PubMed  CAS  Google Scholar 

  4. Eraser GC, Littlejohns JR, Moyle A (1981) The isolation of aprobable pestivirus of goat. Aust Vet J 57: 197–198

    Article  Google Scholar 

  5. Fulton RW, Downing MM, Hagstad HV (1982) Prevalence of bpvine herpesvirus-1, bovine viral diarrhea, parainfluenza-3, bovine adenovirus-3 and 7 and goat respiratory syncytial viral antibodies in goats. Am J Vet Res 43: 1454–1457

    PubMed  CAS  Google Scholar 

  6. Huck RA (1973) Transmission of border disease in goats. Vet Ree 92: 151

    Article  CAS  Google Scholar 

  7. Hyera JMK, Liess B, Frey H-R (1987) A direct neutralizing peroxidase-Hnked antibody assay for detection and titration of antibodies to bovine viral diarrhoea virus. J Vet Med B 34: 227–239

    Article  CAS  Google Scholar 

  8. Hyera LMK (1989) Bovine viral diarrhoea (BVD) in domestic and wild ruminants in northern Tanzania. Diss. Hannover, Vet. School

    Google Scholar 

  9. Liess B, Bhndow H, Orban S, Sasse-Patzer B, Frey H-R, Timm D (1982) Aborte, Totgeburten, Kümmern, Lämmersterben in zwei Schafherden Nordwestdeutschlands—“Border Disease” in der Bundesrepubhk? DTW 89: 6 - 11

    CAS  Google Scholar 

  10. Liess B, Frey H-R, Orban S, Hafez SM (1983) Bovine virusdiarrhoe (BVD)—“Mucosal Disease”: persistente BVD-Feldvirusinfektionen bei serologisch selektierten Rindern. DTW 90: 261–266

    CAS  Google Scholar 

  11. Loken R, Bjerkas I, Hyllseth B (1982) Border disease in goats in Norway. Res Vet Sci 33: 130–131

    PubMed  CAS  Google Scholar 

  12. Loken R (1987) Experimentally-induced border disease in goats. Res Vet Sci 33: 130–131

    Google Scholar 

  13. Loken R (1990) Personal communication

    Google Scholar 

  14. Terpstra C (1981) Border disease: virus persistence, antibody response and transmission studies. Res Vet Sci 30: 185–191

    PubMed  CAS  Google Scholar 

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© 1991 Springer-Verlag

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Depner, K., Hübschle, O.J.B., Liess, B. (1991). BVD-virus infection in goats — experimental studies on transplacental transmissibility of the virus and its effect on reproduction. In: Liess, B., Moennig, V., Pohlenz, J., Trautwein, G. (eds) Ruminant Pestivirus Infections. Archives of Virology, vol 3. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9153-8_31

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  • DOI: https://doi.org/10.1007/978-3-7091-9153-8_31

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82279-1

  • Online ISBN: 978-3-7091-9153-8

  • eBook Packages: Springer Book Archive

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