Skip to main content

Transplantation in Parkinson’s Disease: Stereotactic Implantation of Adrenal Medulla and Foetal Mesencephalon

  • Conference paper
Advances in Stereotactic and Functional Neurosurgery 8

Part of the book series: Acta Neurochirurgica Supplementum ((STEREOTACTIC,volume 46))

Summary

The two possible dopamine donor sites for transplantation are autologous adrenal medulla and human foetal substantia nigra or adrenal medulla. There is increasing experience with the use of adrenal medulla transplantation for Parkinson’s disease and much less experience in foetal substantia nigra transplantation.

The particular problems of each technique are discussed with examples and postoperative progress of cases with the special emphasis on management problems.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Backlund EO, Granberg P, Hamberger B etal (1985) Transplantation of adrenal medullary tissue to striatum in parkinsonism. J Neurosurg 162: 169–172

    Article  Google Scholar 

  2. Bakay RAE, Fuandaca MS, Barrow DL etal (1985) Preliminary report on the use of fetal tissue transplantation to correct MPTP- induced Parkinson-like syndrome in primates. Appl Neurophysiol 48: 358–361

    CAS  PubMed  Google Scholar 

  3. Hitchcock E (1988) Recent experience with dopamine transplantation for Parkinson’s disease. Proceeding of combined meeting Society of British Neurological Surgeons and Neurosurgical Society of Australia, Oxford, 14th April 1988. In press

    Google Scholar 

  4. Koller WC, Perlik S, Nausieda PA etal (1980) Drug holiday and management of Parkinson’s disease. Neurology 30: 1257–1261

    Article  PubMed  Google Scholar 

  5. Lindvall O, Backlund EO, Farde L etal (1987) Transplantation in Parkinson’s disease; two cases of adrenal medullary grafts to the putamen. Ann Neurol 22: 457–468

    Article  CAS  PubMed  Google Scholar 

  6. Madrazo I, Drucker-Colin R, Diaz V etal (1987) Open microsurgical autograft of adrenal medulla to the right caudate nucleus in 2 patients with intractable Parkinsons disease. New Engl J Med No 14, 316: 831–834

    Article  CAS  Google Scholar 

  7. Madrazo I, Leon V, Torres C etal (1987) Transplantation of fetal substantia nigra and adrenal medulla to the caudate nucleus in two patients with Parkinson’s disease. New Engl J Med No 1, 318: 51

    Google Scholar 

  8. Quinn NP (1987) Drug holiday. In: Koller WC (ed) Handbook of Parkinson’s disease. Dekker, New York, pp 328–329

    Google Scholar 

  9. Redmond ED, Roth RH, Elsworth JD etal (1986) Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine. Lancet May 17, 1125–1127

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag

About this paper

Cite this paper

Hitchcock, E.R., Clough, C.G., Hughes, R.C., Kenny, B.G. (1989). Transplantation in Parkinson’s Disease: Stereotactic Implantation of Adrenal Medulla and Foetal Mesencephalon. In: Broggi, G., Burzaco, J., Hitchcock, E.R., Meyerson, B.A., Tóth, S. (eds) Advances in Stereotactic and Functional Neurosurgery 8. Acta Neurochirurgica Supplementum, vol 46. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9029-6_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-9029-6_11

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9031-9

  • Online ISBN: 978-3-7091-9029-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics