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PCR detection of HCV RNA among French non-A, non-B hepatitis patients

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Chronically Evolving Viral Hepatitis

Part of the book series: Archives of Virology ((ARCHIVES SUPPL,volume 4))

Abstract

Hepatitis C virus (HCV) cDNA was amplified from serum of 26/40 French chronic non-A, non-B hepatitis patients by the nested polymerase chain reaction. Compared with anti-C100, viral cDNA represents a more reliable marker of active HCV replication.

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References

  1. Choo Q-L, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M (1989) Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244: 359–362

    Article  PubMed  CAS  Google Scholar 

  2. Kuo G, Choo Q-L, Alter HJ, Gitnick GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, Tegmeier GE, Bonino F, Colombo M, Lee W-S, Kuo C, Berger K, Shuster JR, Overby LR, Bradley DW, Houghton M (1989) An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244: 362–364

    Article  PubMed  CAS  Google Scholar 

  3. Alter HJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo Q-L, Kuo G (1989) Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. Lancet ii: 1494–1500

    Google Scholar 

  4. Boudart D, Lucas JC, Müller J Y, Carrer DL, Planchon B, Harousseau JL (1990) False-positive hepatitis C virus antibody tests in paraproteinaemia. Lancet ii: 63

    Article  Google Scholar 

  5. McFarlane IG, Smith HM, Johnson PJ, Bray GP, Vergani D, Williams R (1990) Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result? Lancet i: 754–755

    Article  Google Scholar 

  6. Theilman L, Blazek M, Goeser T, Gmelin K, Komerell B, Fiehn W (1990) False-positive anti-HCV tests in rheumatoid arthritis. Lancet ii: 1346

    Article  Google Scholar 

  7. Houghton M, Choo Q-L, Kuo G (1989) European patent application No. 0318216A1

    Google Scholar 

  8. Weiner AJ, Kuo G, Bradley DW, Bonino F, Saracco G, Lee C, Rosenblatt J, Choo QL, Houghton M (1990) Detection of hepatitis C viral sequences in non-A, non-B hepatitis. Lancet i: 1–3

    Article  Google Scholar 

  9. Garson JA, Tedder RS, Briggs M, Tuke P, Glazebrook JA, Trute A, Parker D, Barbara JAJ, Conteras M, Aloysius S (1990) Detection of hepatitis C viral sequences in blood donations by “nested” polymerase chain reaction and prediction of infectivity. Lancet i: 1419–1422

    Article  Google Scholar 

  10. Kanai K, Iwata K, Nakao K, Kako M, Okamoto H (1990) Suppression of hepatitis C virus RNA by interferon-oc. Lancet ii: 245

    Article  Google Scholar 

  11. Kaneko S, Unoura M, Kobayashi K, Kuno K, Murakami S, Hattori N (1990) Detection of serum hepatitis C virus RNA. Lancet i: 976

    Article  Google Scholar 

  12. Li JS, Vitvitski L, Tong SP, Trépo C (1990) PCR amplification of HCV sequences from French serum samples and preliminary sequence analysis (1990) Hepatitis B Virus Meeting, La Jolla, California, USA, Abstracts, p 43

    Google Scholar 

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© 1992 Springer-Verlag

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Li, J., Vitvitski, L., Tong, S., Trépo, C. (1992). PCR detection of HCV RNA among French non-A, non-B hepatitis patients. In: De Bac, C., Taliani, G., Gerlich, W.H. (eds) Chronically Evolving Viral Hepatitis. Archives of Virology, vol 4. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5633-9_51

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  • DOI: https://doi.org/10.1007/978-3-7091-5633-9_51

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82350-7

  • Online ISBN: 978-3-7091-5633-9

  • eBook Packages: Springer Book Archive

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