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Osteochondritis Dissecans: Pathoanatomy, Classification, and Advances in Biologic Surgical Treatment

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Bio-orthopaedics

Abstract

Osteochondritis dissecans (OCD) is an articular disorder that results from a pathologic process involving subchondral bone that frequently leads to injury of the overlying articular cartilage. This condition may lead to significant pain and functional impairment, particularly among young athletes. In cases where surgical treatment is considered, a variety of therapeutic options may be used for repair of the injured tissue, including grafting of the osteochondral unit with allograft or autograft, or cell-based cartilage repair. Recent developments that make use of biomaterials and cell-based cartilage repair have demonstrated encouraging results and are an important treatment advancement in this rapidly evolving field of tissue repair.

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Authors and Affiliations

  1. O.A.S.I. Bioresearch Foundation Gobbi NPO, Milan, Italy

    Alberto Gobbi M.D. & Graeme P. Whyte M.D., M.Sc., F.R.C.S.C.

  2. Cornell University, Weill Medical College, New York Presbyterian Hospital/Queens, New York, NY, USA

    Graeme P. Whyte M.D., M.Sc., F.R.C.S.C.

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  1. Alberto Gobbi M.D.
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  2. Graeme P. Whyte M.D., M.Sc., F.R.C.S.C.
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Correspondence to Alberto Gobbi M.D. .

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Editors and Affiliations

  1. O.A.S.I. Bioresearch Foundation NPO, Milan, Italy

    Alberto Gobbi

  2. Clínica do Dragão, Espregueira-Mendes Sports Centre – FIFA Medical Centre of Excellence, Porto, Portugal

    João Espregueira-Mendes

  3. Musculoskeletal and Joint Research Foundation, San Diego, California, USA

    John G. Lane

  4. Department of Orthopedics, Acibadem University, Istanbul, Turkey

    Mustafa Karahan

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Gobbi, A., Whyte, G.P. (2017). Osteochondritis Dissecans: Pathoanatomy, Classification, and Advances in Biologic Surgical Treatment. In: Gobbi, A., Espregueira-Mendes, J., Lane, J., Karahan, M. (eds) Bio-orthopaedics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54181-4_39

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