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The Molecular Genetics of Sepsis: Clinical Epidemiology Considerations

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 2000

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2000))

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Abstract

Advances in molecular genetic research are leading to an ever expanding appreciation of the potential role of genetic variation in predisposition to disease. Although initial work focused on single genetic defects in diseases such as Huntington’s chorea [1, 2] and Alzheimer’s disease [3], recent discoveries have provided insight into susceptibility of a wide range of conditions including many cancers [4–6] and autoimmune inflammatory conditions [7–10]. These observations in autoimmune inflammatory conditions stimulated research into the possibility that there may be an important genetic component to the development and course of infection and sepsis [11–17].

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Authors
  1. R. S. Wax
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  2. D. C. Angus
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Editor information

Editors and Affiliations

  1. Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head Department of Intensive Care) (Head Department of Intensive Care)

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© 2000 Springer-Verlag Berlin Heidelberg

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Wax, R.S., Angus, D.C. (2000). The Molecular Genetics of Sepsis: Clinical Epidemiology Considerations. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2000. Yearbook of Intensive Care and Emergency Medicine, vol 2000. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13455-9_1

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  • DOI: https://doi.org/10.1007/978-3-662-13455-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66830-5

  • Online ISBN: 978-3-662-13455-9

  • eBook Packages: Springer Book Archive

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