Abstract
The results of the initial clinical studies (Phase I and preliminary Phase II evaluation) carried out at the National Cancer Institute of Milan an adriamycin, a 14- hydroxy analogue of daunomycin [1,17], have been reported since 1969 in numerous papers and meetings [2–7, 9–12, 24–26]. Since favorable therapeutic results appeared evident from the first series of patients, the trials have been actively pursued and the drug was tested on a large population of patients with different forms of neoplastic disease.
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Bonadonna, G., Monfardini, S., Lena, M.D., Fossati-Bellani, F., Beretta, G. (1972). Clinical Trials with Adriamycin. Results of Three-Years Study. In: Carter, S.K., Marco, A.D., Ghione, M., Krakoff, I.H., Mathé, G. (eds) International Symposium on Adriamycin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95227-2_15
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