Abstract
Recently, pulsed nuclear magnetic measurements have been made on biological tissues, with the observation first by Damadian [3, 4] and subsequently by others [1, 2, 5–9] that a variety of neoplasms display different spin-lattice (T1) and spin-spin (T2) relaxation times than corresponding normal tissue. These different relaxation times occur with tumors of diverse histologic type, with tumors of human and animal origin, and for tumors transplanted in the live animal or for tumors which have been excised before measurement. Although the physical mechanism of these T1 and T2 values has not yet been determined and is still a matter of controversy, these findings raise the possibility that the principles and techniques of pulsed NMR might be adapted to detection and diagnosis of cancer without the need for surgical intervention.
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References
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Weisman, I.D., Bennett, L.H., Maxwell, L.R., Henson, D.E. (1981). Cancer Detection by NMR in the Living Animal. In: Damadian, R. (eds) NMR in Medicine. NMR Basic Principles and Progress, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87635-6_2
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DOI: https://doi.org/10.1007/978-3-642-87635-6_2
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