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Mode de libération des produits de neurosécrétion

  • Conference paper
Neurosecretion

Résumé

Le mode de libération du neuro-sécrétat dans les vaisseaux irriguant le lobe postérieur demeure un problème très controversé. La Vasopressine et l’ocytocine sont bien véhiculées par les granulations qui viennent s’accumuler à l’extrémité des fibres neuro-sécrétrices, mais ces hormones qui sont des octopeptides n’existent apparemment pas à l’état libre dans les granulations. Elles sont associées à une molécule protéique beaucoup plus volumineuse (Van Dyke et coll., 1942, Hild et Zetler, 1953; Acher, 1958). Acher a désigné cette association protéique sous le terme de «neurophysine». La neurophysine a été isolée et, actuellement, on lui attribue un poids moléculaire de 25.000 (Ginsburg et Ireland, 1963). Au cours de leur libération, les hormones demeurent apparemment associées à leur substrat protéique (van Dyke et coll., 1955; Heller, 1955; Acher, 1958; Ishii et coll., 1962).

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Authors and Affiliations

  1. Laboratoire d’Histologie, Laboratoire de Microscopie électronique, Université Libre de Bruxelles, Belgique

    M. Herlant

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  1. M. Herlant
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F. Stutinsky

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© 1967 Springer-Verlag Berlin Heidelberg

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Herlant, M. (1967). Mode de libération des produits de neurosécrétion. In: Stutinsky, F. (eds) Neurosecretion. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87609-7_4

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  • DOI: https://doi.org/10.1007/978-3-642-87609-7_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87611-0

  • Online ISBN: 978-3-642-87609-7

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