Abstract
SV40 virus-induced tumors and cell cultures transformed by this virus possess new antigens. One antigen studied extensively has been the induced complement-fixation antigen, designated as SV40 “T” or neoantigen (Black et al., 1963; Rapp et al., 1964; Sabin et al., 1964; Habel et al., 1965; Gilden et al., 1965). The antigen can be detected by immunofluorescence techniques as described by Pope and Rowe (1964) employing sera from hamsters bearing noninfectious SV40-induced tumor transplants. In addition to the antigen measured by the complement-fixation (CF) reaction, evidence exists which points to the presence of cellular antigen(s) which are highly effective in promoting development of tumor resistance. This report is concerned with this latter type of antigen.
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Girardi, A.J. (1967). Tumor Resistance and Tumor Enhancement with SV40 Virus-induced Tumors. In: Cottier, H., Odartchenko, N., Schindler, R., Congdon, C.C. (eds) Germinal Centers in Immune Responses. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86837-5_52
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DOI: https://doi.org/10.1007/978-3-642-86837-5_52
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