Skip to main content

Neurogenic Disease and Incontinence: Physiology, Pathophysiology, Diagnostic Imaging, and Urodynamic Studies

  • Chapter
Radiology of the Lower Urinary Tract

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Neuromuscular dysfunction of the bladder and urethra is common; it has been estimated that the prevalence in adults of various forms of dysfunction may be as high as 10% (Friedland and Perkash 1983). The principal reason for this relatively high figure is that neuromuscular bladder dysfunction can be caused by common diseases, including, for example, diabetes mellitus, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease (Dennis et al.

Effect of drugs on the detrusor and urethra

1991; Lose and Colstrup 1991; O’Donnell and BBeck 1991; Lose 1991; van Gool et al. 1992). It is not sufficiently realized, however, how frequent this problem has become with drug therapy. Figure 16.1 illustrates commonly used drugs that can contract or relax the detrusor and urethra. It should be noted that this list includes common drugs like antidepressants and those used for cardiovascular disease, such as β-blockers and calcium channel blockers. As these drugs are now used very widely, it is not surprising that side-effects in the urinary tract occur more often. Unfortunately, such side-effects are frequently not immediately recognized.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Amis SE Jr, Blaivas JG (1990) The role of the radiologist in evaluating voiding dysfunction. Radiology 175: 317 - 318

    PubMed  Google Scholar 

  • Blaivas J (1984) Multichannel urodynamic studies. Urology 23: 421 - 438

    Article  PubMed  CAS  Google Scholar 

  • Blaivas JG, Norlen LJ (1984) Primary bladder neck obstruction. World J Urol 2: 191 - 195

    Article  Google Scholar 

  • Bower GB, Lovegrove FT, Geysel H, Van der Schaff A, Guelfi G (1985) Comparison of “direct” and “indirect” radionuclide cystography. J Nucl Med 26: 465 - 468

    PubMed  CAS  Google Scholar 

  • Brazda JF (1983) Washington Report. The Nation’s Health 13: 3

    Google Scholar 

  • Brocklehurst JC (1986) The aging bladder. Br J Hosp Med 35: 8 - 10

    PubMed  CAS  Google Scholar 

  • Chang PJ (1989) Bayesian analysis revisited: a radiologist’s survival guide. AJR 152: 721 - 727

    PubMed  CAS  Google Scholar 

  • Conway J J (1985) Radionuclide cystography. In: Tauxe WN, Dubovsky EV (eds) Nuclear medicine in clinical urology and nephrology. Appleton-Century-Crofts, Norwalk, Connecticut, pp 305 - 320

    Google Scholar 

  • Cosgriff P, Brown H (1990) Influence of kidney depth on the renographic estimation of relative renal function. J Nucl Med 31: 1576 - 1577

    PubMed  CAS  Google Scholar 

  • Dennis PJ, Rohner TJ Jr, Hu TW, Igou JF, Yu LC, Kaltreider DL (1991) Simple urodynamic evaluation of incontinent elderly female nursing home patients. A descriptive analysis. Urology 37: 173-179

    Google Scholar 

  • Demuylder X, Claes H, Neven P, DeJaegher K (1992) Usefulness of urodynamic investigation in female incontinence. Eur J Obstet Gynecol Reproduct Biol 44: 205 - 208

    Article  CAS  Google Scholar 

  • Drach GW, Binard W (1976) Disposable peak urinary flow meter estimates lower urinary tract obstruction. J Urol 115: 175 - 179

    PubMed  CAS  Google Scholar 

  • Friedland GW (1990) The urethra. Imaging and intervention in the 1990s. Clin Radiol 42: 157 - 160

    Article  PubMed  CAS  Google Scholar 

  • Friedland GW, Perkash I (1983) Neuromuscular dysfunction of the bladder and urethra. Semin Roentgenol 18: 255 - 266

    Article  PubMed  CAS  Google Scholar 

  • Friedland GW, Perkash I (1989) Imaging minzional nelle lesionic neurologiche. In: Pistolesi GF, Bergamo Andreis IA (eds) L’imaging del piccolo bacino funzionale. Libreria Cortina, Verona

    Google Scholar 

  • Friedland GW, Chang P, Perkash I (1989) Imaging examinations in assessment of urethral disease. Prob Urol 3: 820 - 860

    Google Scholar 

  • Ganzer H, Madersbacher H, Rumpl E (1991) Corticoevoked potential by stimulation vesicourethral junction: clinical value and neurophysiologic considerations. J Urol 146: 118 - 123

    PubMed  CAS  Google Scholar 

  • Haid T, Bates P, Bradley WE (1984) The standardization of terminology of lower urinary tract function. International Continence Society, Glasgow, pp 1 - 34

    Google Scholar 

  • Hinman F (1986) Nonneurogenic neurogenic bladder (the Hinman syndrome): 15 years later. J Urol 136: 769 - 777

    PubMed  Google Scholar 

  • Kaplan SA, Chancellor MB, Blaivas JG (1991) Bladder and sphincter behavior in patients with spinal cord lesions. J Urol 146: 113 - 117

    PubMed  CAS  Google Scholar 

  • Kulemeier KV, Lloyd LK, Stover SL (1985) Longterm followup of renal function after spinal cord injury. J Urol 134: 8 - 11

    Google Scholar 

  • Lose G (1991) Urethral pressure and power generation during coughing and voluntary contraction of the pelvic floor in healthy females. Br J Urol 67: 580 - 585

    Article  PubMed  CAS  Google Scholar 

  • Lose G, Colstrup H (1991) Mechanical properties of the urethra in healthy and in stress incontinent females: dynamic measurements in the resting urethra. J Urol 145: 350 - 352

    Google Scholar 

  • Manolin RA (1987) Voiding cystourethrography with synchronous measurements of pressures and flow in the diagnosis of subvesical obstruction in men: radiological view. J Urol 137: 1196 - 1201

    Google Scholar 

  • McNeal J (1983) The prostate gland: morphology and pathobiology. Monogr Urol 4: 3 - 35

    Google Scholar 

  • Nielsen JB, Jensen FT, Munch-Jorgensen T, Charles P, Djurhuus JC (1985) The diagnosis of vesico-ureteral reflux. Scand J Urol Nephrol 19: 109 - 112

    Article  PubMed  CAS  Google Scholar 

  • Nishizawa O, Moysiya I, Sato S, Harada T, Tsuchida S (1982) A new videourodynamies: combined ultrasonographic and urodynamic monitoring. Neurol Urodynam 1: 295 - 301

    Article  Google Scholar 

  • O’Donnell PD, Beck C (1991) Urinar incontinence volume, patterns in elderly inpatient men. Urology 38: 128 - 131

    Article  PubMed  Google Scholar 

  • Perkash I, Friedland GW (1984) Using transrectal sonography to teach patients with spinal cord injuries to retrain their bladders. Radiology 152: 228 - 229

    PubMed  CAS  Google Scholar 

  • Perkash I, Friedland GW (1985) Real-time gray-scale transrectal linear array ultrasonography in urodynamic evaluation. Semin Urol 3: 49 - 59

    PubMed  CAS  Google Scholar 

  • Perkash I, Friedland GW (1986a) Posterior ledge of the bladder neck: the crucial diagnostic role of ultrasonography. Urol Radiol 8: 175 - 183

    Article  PubMed  CAS  Google Scholar 

  • Perkash I, Friedland GW (1986b) Transrectal ultrasonography of the lower urinary tract: evaluation of bladder neck problems. Neuroradiol Urodynam 5: 299 - 306

    Article  Google Scholar 

  • Perkash I, Friedland GW (1986c) Catheter-induced hyperreflexia in spinal cord injury patients. Diagnosis by sonographic voiding cystourethrography. Radiology 159: 453-455

    Google Scholar 

  • Perkash I, Friedland GW (1987a) Principles of modern urodynamic studies. Invest Radiol 22: 279 - 289

    Article  PubMed  CAS  Google Scholar 

  • Perkash I, Friedland GW (1987b) Ultrasonographic detection of false passages arising from the posterior urethra in spinal cord injury patients. J Urol 137: 701 - 702

    PubMed  CAS  Google Scholar 

  • Peters AM, Morony S, Gordon I (1990) Indirect radionuclide cystography demonstrates reflux under physiological conditions. Clin Radiol 41: 44 - 47

    Article  PubMed  CAS  Google Scholar 

  • Porena M, Vespaspiani G, Vergili G, Lombi R, Mearini E, Rosi P, Micali F (1987) Real-time transrectal sonographic voiding cystourethrography. Urology 30: 171 - 175

    Article  PubMed  CAS  Google Scholar 

  • Raz S, Smith RB (1976) External sphincter spasticity syndrome in female patients. J Urol 115: 443 - 446

    PubMed  CAS  Google Scholar 

  • Resnick M, Yalla SV (1985) Management of urinary incontinence in the elderly. N Engl J Med 313: 800 - 805

    Article  PubMed  CAS  Google Scholar 

  • Resnick NM, Yalla SV (1987) Detrusor hyperactivity with impaired contractile function. JAMA 257: 3076 - 3081

    Article  PubMed  CAS  Google Scholar 

  • Schmidt RA (1991) Urodynamics simplified. Urology 35: 449 - 454

    Article  Google Scholar 

  • Sfakianakis GN, Snuclovisky C, Strauss J, Hourani M, Lockhart G, Zilleruelo G, Freudlick M (1984) Improving the technique of nuclear cystography. Manometric approach. J Urol 131: 1061-1064

    Google Scholar 

  • Shabsign R, Fishman TJ, Krebs M (1987) The use of transrectal longitudinal real-time ultrasonography in urodynamics. J Urol 138: 1416 - 1419

    Google Scholar 

  • Shapeero G, Friedland GW, Perkash I (1983) Transrectal sonographic voiding cystourethrography. Studies in neuromuscular dysfunction. AJR 141: 83-90

    Google Scholar 

  • Tanagho AE, Schmidt RA (1982) Bladder pacemaker: scientific basis and clinical future. Urology 20: 614 - 619

    Article  PubMed  CAS  Google Scholar 

  • Tauxe WN, Dubovsky EV, Kidd T, Diaz F, Smith LR (1982) New formulas for the calculation of effective renal plasma flow. Eur J Nucl Med 7: 51 - 54

    PubMed  CAS  Google Scholar 

  • Tempkin A, Sullivan G, Paldi J, Perkash I (1985) Radioisotope renography in spinal cord injury. J Urol 133: 228 - 230

    PubMed  CAS  Google Scholar 

  • VanGool JD, VijVerberg MA, Messer AP, Elzinger-Plomp A, Van Jong TP (1992) Functional daytime incontinence: clinical and urodynamic assessment. Scan J Urol Nephrol Supplement 141: 58 - 69

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Friedland, G.W., Perkash, I., Segall, G.M. (1994). Neurogenic Disease and Incontinence: Physiology, Pathophysiology, Diagnostic Imaging, and Urodynamic Studies. In: Lang, E.K. (eds) Radiology of the Lower Urinary Tract. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84431-7_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84431-7_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84433-1

  • Online ISBN: 978-3-642-84431-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics