Abstract
Neuromuscular dysfunction of the bladder and urethra is common; it has been estimated that the prevalence in adults of various forms of dysfunction may be as high as 10% (Friedland and Perkash 1983). The principal reason for this relatively high figure is that neuromuscular bladder dysfunction can be caused by common diseases, including, for example, diabetes mellitus, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease (Dennis et al.
1991; Lose and Colstrup 1991; O’Donnell and BBeck 1991; Lose 1991; van Gool et al. 1992). It is not sufficiently realized, however, how frequent this problem has become with drug therapy. Figure 16.1 illustrates commonly used drugs that can contract or relax the detrusor and urethra. It should be noted that this list includes common drugs like antidepressants and those used for cardiovascular disease, such as β-blockers and calcium channel blockers. As these drugs are now used very widely, it is not surprising that side-effects in the urinary tract occur more often. Unfortunately, such side-effects are frequently not immediately recognized.
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Friedland, G.W., Perkash, I., Segall, G.M. (1994). Neurogenic Disease and Incontinence: Physiology, Pathophysiology, Diagnostic Imaging, and Urodynamic Studies. In: Lang, E.K. (eds) Radiology of the Lower Urinary Tract. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84431-7_16
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DOI: https://doi.org/10.1007/978-3-642-84431-7_16
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