Abstract
The immune response against most antigens or infections shows a characteristic pattern of effector functions, typical of that antigen. For many pathogens, the immune response is appropriate, i.e. the effector functions are capable of neutralising or eliminating the infection. Examples include the induction of antibodies to neutralize toxins, cytotoxic T lymphocytes (CTLs) to kill virus-infected cells, and Delayed Type Hypersensitivity against intracellular pathogens. The mechanisms controlling this immune class regulation have been difficult to determine until recently, when two functionally different types of T cell were defined according to their different patterns of cytokine synthesis. These two T cell types appear to be responsible for at least part of immune class regulation.
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© 1989 Springer-Verlag Berlin Heidelberg
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Mosmann, T.R. et al. (1989). Heterogeneity of Mouse Helper T Cells and Cross-Regulation of TH1 and TH2 Clones. In: Melchers, F., et al. Progress in Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83755-5_82
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DOI: https://doi.org/10.1007/978-3-642-83755-5_82
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-83757-9
Online ISBN: 978-3-642-83755-5
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