Abstract
This is a summary of some of the research taking place in our laboratory. The paper represents a condensed version of a recent review paper (Unanue et al ., 1989).
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References
Allen, P.M., B.P. Babbitt, and E.R. Unanue. 1987. T-cell recognition of lysozyme: the biochemical basis of presentation. Immunol. Reviews 98: 171
Allen, P.M., G.R. Matsueda, R.J. Evans., J.B. Dunbar. Jr., G. Marshall, and E.R. Unanue. 1987b. Identification of the T-cell and la contact residues of a T-cell antigen epitope. Nature 327: 713.
Babbitt, B.P., P.M, Allen, G. Matsueda., and E.R. Unanue. 1985. Binding of immunogenic peptides to la histocompatibility molecules. Nature 317: 359
Babbitt. B.P., G. Matsueda, E. Haber, E.R. Unanue, and P.M. Allen, 1986. Antigenic competition at the level of peptide — Ia binding. Proc. Natl. Acad. Sci. 83: 4509.
Bjorkman, P.J., M.A. Saper, B. Samraoui, W.S. Bennett, J.L Strominger, and D.C. Wiley, 1987. Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329: 506.
Bjorkman, P.J., M.A. Saper, B. Samraoui, W.S. Bennett, J.L Strominger, and D.C. Wiley, 1988. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 329: 512.
Brown, J.H., T. Jardetzsky, M.A. Saper, B. Samraoui, P. Bjorkman, and D.C. Wiley. 1988. A hypothetical model of the foreign antigen binding site of class II histocompatibility antigens. Nature 332: 845.
Buus, S. A. Sette. S.M. Colon. D.M. Jenis, and H.M. Grey. 1986a. Isolation and characterization of antigen-Ia complexes involved in T cell recognition. Cell 47: 1071.
Buus, S. S. Colon. C. Smith. J.H. Freed, C. Miles, and H.M. Grey. 1986b. Interaction between a “processed” ovalbumin peptide and Ia molecules. Proc. Natl. Acad. Sci. 83: 3968.
Creswell, P. 1985. Intracellular class II HLA antigens are accessible to transferin-neuraminidase congregates internalized by receptor-mediated endocytosis. Proc. Natl. Acad. Sci. (USA) 82: 8188.
Guillet, J.G. M.Z. Lai and T.J. Briner. 1987. Immunological self, non-self discrimination. Science 235: 865.
Harding, C.V. and E.R. Unanue. 1989. Antigen processing and intracellular Ia. Possible role of endocytosis and protein synthesis in Ia function. J. Immunol. 142: 12.
Harding, C.V., F. Leyva-Cobian, E.R. Unanue, 1988. Mechanisms of antigen processing. Immunological Reviews 106: 77.
Harding C.V., R. M. Roof, and E.R. Unanue, 1989. Turnover of Ia-peptide complexes is facilitated in viable antigen presenting cells: Biosynthetic turnover of Ia vs. peptide exchange. Proc. Natl. Acad. Sci. (USA) 86: 4230.
Lambert. L.E. and E.R. Unanue, 1989. Analysis of the interaction of the lysozyme peptide HEL(34–45) with the I-Ak molecule. J. Immunol.-in press.
Lippincott-Schwartz, J., L.C. Yuan, J.S. Bonifacino, R.D. Klausner, 1989. Rapid redistribution of Golgi proteins into the ER in cells treated with Brefeldin A: Evidence for membrane cycling from Golgi to ER. Cell 56: 801.
Luescher, I.F., P.M. Allen, E.R. Unanue, 1988. Binding of photoreactive lysozyme peptides to murine histocompatibility class II molecules. Proc. Natl. Acad. Sci. 85: 871.
Morrison, L.A., A.E. Lukacher, V.L. Braciale, D. Fan, and T.J. Braciale. 1986. Differences in antigen presentation to MHC Class I-and Class II-restricted influenza virus specific T lymphocyte clones. J. Exp. Med. 163: 903.
Unanue, E.R. and P.M. Allen, 1987. The basis for the immunoregulatory role of macrophages and other accessory cells. Science 236: 551.
Unanue, E.R., C.V. Harding, I.F. Luescher, and R.W. Roof. 1989. Antigen-Binding function of class II-MHC molecules. LIV Symposium on Quantitative Biology, Cold Springer Harbor
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© 1989 Springer-Verlag Berlin Heidelberg
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Unanue, E.R., Harding, C.V., Luescher, I.F., Roof, R.W. (1989). Further Analysis of the Role of MHC Molecules in Antigen Presentation. In: Melchers, F., et al. Progress in Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83755-5_8
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DOI: https://doi.org/10.1007/978-3-642-83755-5_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-83757-9
Online ISBN: 978-3-642-83755-5
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