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Reconstruction of Large Diaphyseal Defects by Autoclaved Reimplanted Bone: An Experimental Study in the Rabbit

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Bone Transplantation

Abstract

Limb-preserving surgery by local resection has become increasingly applied in the treatment of malignant bone tumours as an alternative to ablative surgery [5, 12, 13, 16]. However, the mandatory requirement for radicality often leads to extensive resections causing considerable problems of reconstruction. Several means of substituting skeletal defects have been tried both experimentally and clinically [1, 5–7]. At present, the methods most widely used in clinical practice seem to be endoprosthetic replacement and bone transplantation, either autologous or allogeneic [5, 12, 16].

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References

  1. Albrektsson B (1971) Repair of diaphyseal defects. Experimental studies on the role of bone grafts in reconstruction of circumferential defects in long bones. Thesis, Gothenburg

    Google Scholar 

  2. American Association of Tissue Banks (1980) Guidelines for the banking of musculoskeletal tissues. Am Assoc Tissue Banks Newslett 4: 30

    Google Scholar 

  3. Burwell GR (1969) The fate of bone grafts. In: Apley AG (ed) Recent advances in orthopaedics. Churchill, London

    Google Scholar 

  4. Carnesale PL, Spankus JD (1959) A clinical comparative study of autogenous and homogenous bone grafts. J Bone Joint Surg [Am] 41: 887

    Google Scholar 

  5. Enneking WF, Eady JL, Burchardt H (1980) Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects. J Bone Joint Surg [Am] 60: 1039

    Google Scholar 

  6. Friedlaender GE, Strong DM, Sell KW (1976) Studies of the antigenicity of bone freeze-dried and deep frozen allografts in rabbits. J Bone Joint Surg [Am] 58: 854

    CAS  Google Scholar 

  7. Johnston JO, Harries TJ, Alexander CE, Alexander AH (1983) Limb salvage procedure for neoplasms about the knee by spherocentric total knee arthroplasty and autogenous autoclaved bone grafting. Clin Orthop 181: 137

    PubMed  Google Scholar 

  8. Jonsson U, Strömberg L (1985) Torsional tests of long bones with computerized equippement. J Biomed Eng 7: 251

    Article  PubMed  CAS  Google Scholar 

  9. Key AJ (1934) The effect of a local calcium depot on osteogenesis and healing of fractures. J Bone Joint Surg 132: 176

    Google Scholar 

  10. Kirkup JR (1965) Traumatic femoral bone loss. J Bone Joint Surg [Br] 47: 106

    CAS  Google Scholar 

  11. Ku JL, Smith PA, Goldstein SA, Matthews LS (1985) An experimental investigation of the fate of autogenous autoclaved bone grafts. 31st Annual ORS Las Vegas, Nevada, January 1985

    Google Scholar 

  12. Mankin HJ, Doppelt SH, Sullivan RT, Tomford WW (1982) Osteoarticular and intercalary allograft transplantation in the management of malignant tumors of bone. Cancer 50: 613

    Article  PubMed  CAS  Google Scholar 

  13. Moore RJ, Weiland AJ, Daniel RK (1983) Use of free vascularized bone grafts in the treatment of bone tumors. Clin Orthop 175: 37

    PubMed  Google Scholar 

  14. Orell S (1934) Studien über Knochenimplantation and Knochenneubildung, Implantation von „os purum“ sowie Transplantation von „os novum”. Acta Chir Scand 74 [Suppl]: 31

    Google Scholar 

  15. Orell S (1937) Surgical bone grafting with os purum, os novum and boiled bone. J Bone Joint Surg 19: 873

    Google Scholar 

  16. Ottolenghi CE (1972) Massive osteo and osteo-articular bone grafts. Clin Orthop 87: 156

    Article  PubMed  CAS  Google Scholar 

  17. Rivard CH (1984) The effect of autoclaving on normal and sarcomatous bone cells and on graft incorporation. Current concepts of diagnosis and treatment of bone and soft tissue tumours. Springer, Berlin Heidelberg New York

    Google Scholar 

  18. Rohlin M, Larsson A, Hammarström L (1977) Distribution of Tc-99m labelled phosphorous compounds, Ca-45 and 85-Sr in diphosphonate-treated rats. Acta Radiol Phys Biol 16: 513

    CAS  Google Scholar 

  19. Sijbrandij S (1978) Resection and reconstruction for bone tumours. Acta Orthop Scand 49: 249

    Article  PubMed  CAS  Google Scholar 

  20. Smith WS, Simon MA (1975) Segmental resection for chondrosarcoma. J Bone Joint Surg [Am] 57: 1097

    CAS  Google Scholar 

  21. Sorenson JA, Cameron JR (1967) A reliabel in vivo measurement of bone-mineral content. J Bone Joint Surg [Am] 49: 481

    CAS  Google Scholar 

  22. Stabler CL, Eismont FJ, Brown MD, Green BA, Malinin TI (1985) Failure of posterior cervical fusion using cadaveric bone graft in children. J Bone Joint Surg [Am] 67: 370

    Google Scholar 

  23. Thompson VP, Stagall CT (1956) Chondrosarcoma of the proximal portion of the femur treated by resection and bone replacement. J Bone Joint Surg [Am] 38: 357

    Google Scholar 

  24. Tuli SM, Singh AD (1978) The osteoinductive property of decalcified bone matrix. J Bone Joint Surg [Br] 60: 116

    CAS  Google Scholar 

  25. Urist MR, Silverman BF, Buring K, Dubuc FL, Rosenberg JM (1967) The bone induction principle. Clin Orthop 53: 243

    PubMed  CAS  Google Scholar 

  26. Urist MR, Mikuliski A, Boyd SD (1975) A chemosterilized antigen-extracted autodigested alloimplant for bone banks. Arch Surg 110: 416

    Article  PubMed  CAS  Google Scholar 

  27. Urist MR, Dawson E (1981) Intertransverse process fusion with the aid of chemosterilized autolyzed antigen-extracted allogeneic ( AAA) bone. Clin Orthop 154: 97

    PubMed  Google Scholar 

  28. Wittbjer J (1983) Bone matrix and bone formation. An experimental study of demineralized bone reimplanted in bone defects. Thesis, Malmö

    Google Scholar 

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© 1989 Springer-Verlag, Berlin Heidelberg

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Kreicbergs, A., Köhler, P. (1989). Reconstruction of Large Diaphyseal Defects by Autoclaved Reimplanted Bone: An Experimental Study in the Rabbit. In: Aebi, M., Regazzoni, P. (eds) Bone Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83571-1_34

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  • DOI: https://doi.org/10.1007/978-3-642-83571-1_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83573-5

  • Online ISBN: 978-3-642-83571-1

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