Abstract
Radiation therapy plays an essential role in the management of patients with head and neck cancers. Radiotherapy is the preferred single modality treatment for the majority of patients with small lesions (e.g., T1 and T2 tumors) since it is as effective as surgery in the local eradication of the neoplastic disease but, in general, produces less functional impairment and less cosmetic deformity. Combinations of surgery and radiation therapy are recommended for patients with advanced locoregional disease. The rationale behind combined treatment is that surgical resection of gross tumor eliminates the most common cause of radiotherapeutic failure, whereas radiotherapy is more efficient at sterilizing microscopic tumor beyond the margins of the surgical resection. Unfortunately, radiation doses required in these clinical settings do induce transient normal tissue injuries, functional deficits, and occasionally, persistent complications.
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Ang, K.K., Stephens, L.C., Schultheiss, T.E. (1991). Oral Cavity and Salivary Glands. In: Scherer, E., Streffer, C., Trott, KR. (eds) Radiopathology of Organs and Tissues. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83416-5_10
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