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Introduction

  • Chapter
HLA in Narcolepsy

Abstract

Recent findings that all, or almost all, narcoleptic patients typed for human leukocyte antigen (HLA) are DR2 and DQw1 positive indicate that of all HLA-associated diseases, narcolepsy has by far the strongest association with HLA. Thus narcolepsy must be considered a special disease from the molecular biologist’s point of view. In addition, the fact that narcolepsy has a close relationship with HLA genes provides promising clues for molecular biological research on sleep and arousal disorders.

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Authors
  1. Y. Honda
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Editors and Affiliations

  1. Neuropsychiatric Research Institute, Seiwa Hospital, 91 Bentencho, Shinjuku-ku, Tokyo, 162, Japan

    Yutaka Honda MD, DMedSc

  2. Blood Transfusion Service, Tokyo University Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113, Japan

    Takeo Juji MD, DMedSc

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© 1988 Springer-Verlag Berlin Heidelberg

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Honda, Y. (1988). Introduction. In: Honda, Y., Juji, T. (eds) HLA in Narcolepsy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83387-8_1

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  • DOI: https://doi.org/10.1007/978-3-642-83387-8_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83389-2

  • Online ISBN: 978-3-642-83387-8

  • eBook Packages: Springer Book Archive

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