Abstract
Over the past 3 decades the incidence and mortality from melanoma in Canada, the United Kingdom, United States, Australia and the Nordic countries has increased dramatically (Elwood and Lee 1974; Kopf et al. 1984; Little et al. 1980; Magnus 1977; Muir and Nectoux 1982). A number of factors have been linked aetiologically with melanoma, including host factors such as light skin, hair and eye colour (Elwood et al. 1984; Gellin et al. 1969; Holman and Armstrong 1984 a; Lancaster and Nelson 1957). There is evidence that risk of melanoma is related to sunlight exposure (Elwood and Hislop 1982; Holman et al. 1983), although the relationship is obviously not a simple one. It has been suggested that intermittent heavy sunlight exposure may be more important than constant dose in risk of superficial spreading melanomas, and this theory is supported by findings of similarity of incidence rates by unit area on usually and intermittently exposed body sites (Elwood and Gallagher 1983).
Financial support for this study was provided by Health & Welfare Canada (NHRDP 6610-1203-53), the National Cancer Institute of Canada, and the Alberta Heritage Trust Fund
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adam SA, Sheaves JK, Wright NH, Mosser G, Harris RW, Vessey VP (1981) A case-control study of the possible association between oral contraceptives and malignant melanoma. Br J Cancer 44: 45 - 50
Alderson MR, Clarke JA (1983) Cancer incidence in patients with psoriasis. Br J Cancer 47: 857 - 859
Bain C, Hennekens CH, Speizer FE, Rosner B, Willett W, Belanger C (1982) Oral contraceptive use and malignant melanoma. JNCI 68: 537 - 539
Balda BR, Hehlmann R, Cho JR, Spiegelman S (1975) Oncornavirus-like particles in human skin cancers. Proc Natl Acad Sci USA 72: 3697 - 3700
Beitner H, Ringborg U, Wennersten G, Lagerlof B (1981) Further evidence for increased light sensitivity in patients with malignant melanoma. Br J Dermatol 104: 289 - 294
Beral V, Ramcharan S, Faris R (1977) Malignant melanoma and oral contraceptive use among women in California. Br J Cancer 36: 804 - 809
Beral V, Evans S, Shaw H, Milton G (1983) Cutaneous factors related to risk of malignant melanoma. Br J Dermatol 109: 165 - 172
Beral V, Evans S, Shaw H, Milton G (1984) Oral contraceptive use and malignant melanoma in Australia. Br J Cancer 50: 681 - 685
Breslow NE, Day NE (1980) Statistical methods in cancer research, vol 1. The analysis of case control studies. IARC Sci Publ 32
Brodthagen H (1982) Malignant melanoma caused by UV - A suntan bed? Acta Derm Venereol (Stockh) 62: 356 - 357
Clark WH, Mihm MC (1969) Lentigo maligna and lentigo-maligna melanoma. Am J Pathol 55: 39 - 67
Elwood JM, Gallagher RP (1983) Site distribution of malignant melanoma. Can Med Assoc J 128: 1400 - 1404
Elwood JM, Hislop TG (1982) Solar radiation in the etiology of cutaneous melanoma in Caucasians. Natl Cancer Inst Monogr 62: 167 - 171
Elwood JM, Lee JAH (1974) Trends in mortality from primary tumours of the skin in Canada. Can Med Assoc J 110: 913 - 915
Elwood JM, Gallagher RP, Hill GB, Spinelli JJ, Pearson JCG, Threlfall W (1984) Pigmentation and skin reaction to sun as risk factors for cutaneous melanoma. Western Canada Melanoma Study. Br Med J I: 99 - 102
Elwood JM, Gallagher RP, Hill GB, Pearson JCG (1985a) Cutaneous melanoma in relation to intermittent and constant sun exposure - The Western Canada Melanoma Study. Int J Cancer 35: 427 - 433
Elwood JM, Gallagher RP, Davison J, Hill GB (1985b) Sunburn, suntan, and risk of cutaneous malignant melanoma: Western Canada Melanoma Study. Br J Cancer 51: 543-549
Flax H, Salih H, Westbury G (1973) Hormone therapy in malignant melanoma. Lancet II: 147
Gallagher RP, Elwood JM, Hill GB, Coldman AJ, Threlfall WJ, Spinelli JJ (1985) Reproductive fac-tors, oral contraceptives and risk of malignant melanoma: Western Canada melanoma study. Br J Cancer 52: 901-907
Gellin GA, Kopf AW, Garfinkel L (1969) Malignant melanoma: a controlled study of possibly associated factors. Arch Dermatol 99: 43 - 48
Helmrich S, Rosenberg L, Kaufman DW, Miller DR, Schottenfeld D, Stolley PD, Shapiro S (1984) Lack of an elevated risk of malignant melanoma in relation to oral contraceptive use. JNCI 72: 617 - 620
Holly EA, Weiss NS, Liff JM (1983) Cutaneous melanoma in relation to exogenous hormones and reproductive factors. JNCI 70: 827 - 831
Holman CDJ (1982) Risk factors in the causation of human malignant melanoma of the skin. Ph. D. Thesis, University of Western Australia, Perth, pp 418 - 423
Holman CD, Armstrong BK (1984a): Pigmentary traits, ethnic origin, benign nevi and family history as risk factors for cutaneous malignant melanoma. JNCI 72: 257-266
Holman CDJ, Armstrong BK (1984b) Cutaneous malignant melanoma and indicators of total accu-mulated exposure to the sun: an analysis separating histogenetic types. JNCI 73: 75 - 82
Holman CDJ, Armstrong BK, Heenan PJ (1983) A theory of the etiology and pathogenesis of human cutaneous malignant melanoma. JNCI 71: 651 - 656
Holman CDJ, Armstrong BK, Heenan PJ (1984) Cutaneous malignant melanoma in women: exogenous sex hormones and reproductive factors. Br J Cancer 50: 673 - 680
Ito R, Mishima Y (1967) Particles in the cisternae of the endoplasmic reticulum of Fortner’s amelanotic and melanotic malignant melanoma. J Invest Dermatol 48: 268 - 272
Klepp O, Magnus K (1979) Some environmental and bodily characteristics of melanoma patients. A case-control study. Int J Cancer 23: 482-486
Kopf AW, Kripke ML, Stern RS (1984) Sun and malignant melanoma. J Am Acad Dermatol 11: 674 - 684
Krupp MA, Chatton MJ (1982) Current medical diagnosis and treatment 1982. Lange Medical, Los Altos, California, pp 50 - 51
Lancaster HO, Nelson J (1957) Sunlight as a cause of melanoma: a clinical survey. Med J Aust 1: 452 - 456
Lee JAH, Strickland D (1980) Malignant melanoma: social status and outdoor work. Br J Cancer 41: 757 - 763
Lew RA, Sober AJ, Cook N, Marvell R, Fitzpatrick TB (1983) Sun exposure habits in patients with cutaneous melanoma: a case-control study. J Dermatol Surg 9: 981 - 986
Little JH, Holt J, Davis N (1980) Changing epidemiology of malignant melanoma in Queensland. Med J Aust 1: 66 - 69
MacKie RM, Aitchison T (1982) Severe sunburn and subsequent risk of primary cutaneous malignant melanoma in Scotland. Br J Cancer 46: 955 - 960
McGovern VJ, Caldwell RA, Duncan CA, Finlay-Jones LR, Hardy EG, Hicks JD, Little JH, Quinn RL (1967) Moles and malignant melanoma: terminology and classification. Med J Aus I: 123 - 124
McGovern VJ, Shaw HM, Milton GW, Farago GA (1979) Is malignant melanoma arising in a Hutchinson’s melanotic freckle a separate disease entity? Histopathology 4: 235 - 242
Magnus K (1977) Incidence of malignant melanoma in the five nordic countries. Int J Cancer 20: 477 - 486
Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. JNCI 22: 719 - 748
Muir CS, Nectoux J (1982) Time trends: malignant melanoma of the skin. In: Magnus K (Ed) Trends in cancer incidence: causes and implications. Hemisphere, New York, pp 365 - 388
Nicholls EM (1968) Genetic susceptibility and somatic mutation in the production of freckles, birth-marks and moles. Lancet I: 71 - 73
Rampen FHJ, Mulder JH (1980) Malignant melanoma: an androgen dependent tumour? Lancet I: 562
Retsas S (1983) Sun beds and melanoma. Br Med J 286: 892
Swerdlow AJ, English J, Mackie RM, O’Doherty CJ, Hunter JAA, Clark J (1984) Benign nevi associated with high risk of melanoma. Lancet II: 168
Waterhouse J, Muir C, Shanmugaratnam K, Powell J (1982) Cancer incidence in five continents, vol IV. IARC Sci Publ 42
Williams RR, Horm JJ (1977) Association of cancer sites with tobacco and alcohol consumption and socio-economic status of patients: interview study from the Third National Cancer Survey. JNCI 58: 525 - 547
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Gallagher, R.P., Elwood, J.M., Hill, G.B. (1986). Risk Factors for Cutaneous Malignant Melanoma: The Western Canada Melanoma Study. In: Gallagher, R.P. (eds) Epidemiology of Malignant Melanoma. Recent Results in Cancer Research, vol 102. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82641-2_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-82641-2_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-82643-6
Online ISBN: 978-3-642-82641-2
eBook Packages: Springer Book Archive