Abstract
The multifrequency human time structure represents a challenge for sampling and interpreting laboratory measurements. However, it also represents an opportunity for refining the diagnostic value of the measurement of many variables showing high amplitude rhythms and opens a new field in laboratory diagnosis. Statistically quantified rhythm parameters, and their relation to astronomic time and to each other, can serve as new end points in defining normality and in recognizing deviations from time-qualified reference values, including reference values to be established for the rhythm parameters themselves.
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Haus, E., Touitou, Y. (1992). Chronobiology in Laboratory Medicine. In: Touitou, Y., Haus, E. (eds) Biologic Rhythms in Clinical and Laboratory Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78734-8_47
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