Skip to main content
SpringerLink
Log in

Morphology of Dupuytren’s Disease

  • Conference paper
Dupuytren’s Disease

Abstract

Dupuytren’s disease has a prevalence of 1%–3% (Viljanto 1973) and usually occurs in middle aged or elderly men (gt;40 years). Females suffer much less frequently from this disorder (Fig. 1), as shown by Yost et al. (1955), who found a male:female ratio of 3:1. Although there is an often mentioned “causal” association with diabetes mellitus (Pal et al. 1987), this is not etiologically significant.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Allen PW (1977) The fibromatoses: a clinicopathologic classification based on 140 cases. Am J Surg Pathol 1: 255–270

    Article  PubMed  CAS  Google Scholar 

  • Andrew JG, Ash A, Turner B, Andrew SM (1990) The role of inflammatory cells in Dupuytrens contracture: an immunohistochemical study ( Abstr ). J Bone Joint Surg [Br] 72: 1110

    Google Scholar 

  • Azizkhan RG, Clifford Azizkhan J, Zetter BR, Folkman J (1980) Mast cell heparin stimulates migration of capillary endothelial cells in vitro. J Exp Med 152: 931–944

    Article  PubMed  CAS  Google Scholar 

  • Beranek JT, Cavarocchi NC (1990) Histogenesis of the intimal thickening in atherosclerosis and of hyperplastic processes in connective tissue. Hum Pathol 21: 1082–1083

    Article  PubMed  CAS  Google Scholar 

  • Brax P (1992) Pathologisch-anatomische und pathogenetische Aspekte der pigmentierten villomodularen Synovialitis. Medical dissertation, University of Ulm

    Google Scholar 

  • Brooks J J (1986) The significance of double phenotypic patterns and markers in human sarcomas. A new model of mesenchymal differentiation. Am J Pathol 125: 113–123

    PubMed  CAS  Google Scholar 

  • Claman HN (1989) Mast cell changes in a case of rapidly progressive scleroderma - ultrastructural analysis. J Invest Dermatol 92: 290–295

    Article  PubMed  CAS  Google Scholar 

  • Diaz-Flores L, Dominguez C (1985) Relation between arterial intimal thickening and the vasa-vasorum. Virchows Arch [A] 406: 165–177

    Article  CAS  Google Scholar 

  • Druvefors P, Norrby K (1988) Molecular aspects of mast-cell-mediated mitogenesis in fibroblasts and mesothelial cells in situ. Virchows Arch [Cell Pathol] 55: 187–192

    CAS  Google Scholar 

  • Falanga V, Soter NA, Altaian RD, Kerdel FA (1990) Elevated plasma histamine levels in systemic sclerosis (scleroderma). Arch Dermatol 126: 336–338

    Article  PubMed  CAS  Google Scholar 

  • Ghadially FN (1983) Fine structure of synovial joints. Butterworth, London

    Google Scholar 

  • Hatamochi A, Fuji war a K, Ueki H (1985) Effects of histamine on collagen synthesis by cultured fibroblasts derived from guinea pig skin. Arch Dermatol Res 277: 60–64

    Google Scholar 

  • Krsti RV (1984) Illustrated encyclopedia of human histology. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Luck JV (1959) Dupuytren’s contracture. J Bone Joint Surg [Am] 41: 635–664

    Google Scholar 

  • Marks RM, Roche WR, Czerniecki M, Penny R, Nelson DS (1986) Mast cell granules cause proliferation of human microvascular endothelial cells. Lab Invest 55: 289–294

    PubMed  CAS  Google Scholar 

  • Mechtersheimer G, Moller P (1990) Expression of Ki-1 antigen (CD30) in mesenchymal tumors. Cancer 66: 1732–1737

    Article  PubMed  CAS  Google Scholar 

  • Meister P, Gokel JM, Remberger K (1979) Palmar fibromatosis - “Dupuytren’s contracture”. A comparison of light electron and immunofluorescent microscopic findings. Pathol Res Pract 16: 402–412

    Google Scholar 

  • Mohr W (1983) Pathologie der Dupuytren’schen Krankheit. Med Welt 34: 397–404

    PubMed  CAS  Google Scholar 

  • Mohr W (1987) Pathologie des Bandapparates. Sehnen, Sehnenscheiden, Faszien, Schleimbeutel. In: Doerr W, Seifert G (eds) Spezielle pathologische Anatomie, vol 19. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Mohr W, Vossbeck G (1985) Untersuchungen zur Proliferation und 3H-Prolin-Inkorporation von Zellen der Palmarfibromatose ( Morbus Dupuytren ). Z Rheumatol 44: 226–230

    Google Scholar 

  • Murrell GAC, Francis MJO, Howlett CR (1989) Dupuytren’s contracture. Fine structure in relation to aetiology. J Bone Joint Surg [Br] 71: 367–373

    Google Scholar 

  • Pal B, Griffiths ID, Anderson J, Dick WC (1987) Association of limited joint mobility with Dupuytren’s contracture in diabetes mellitus. J Rheumatol 14: 582–585

    PubMed  CAS  Google Scholar 

  • Roholl PJM, Elbers HR, Prinsen I, Claessens JAJ, van Unnik JAM (1990) Distribution of actin isoforms in sarcomas: an immunohistochemical study. Hum Pathol 21: 1269–1274

    Article  PubMed  CAS  Google Scholar 

  • Sandberg N (1962) Accelerated collagen formation and histamine. Nature 194: 183

    Article  PubMed  CAS  Google Scholar 

  • Sarkisov DS, Kolocolchicova EG, Varava BN, Tjurmin AV, Peclo MM, Printseva OY (1989) Morphogenesis of intimal thickening in nonspecific aortoarteritis. Hum Pathol 20: 1048–1056

    Article  PubMed  CAS  Google Scholar 

  • Skalli O, Schiirch W, Seemayer T, Lagace R, Montandon D, Pittet B, Gabbiani G (1989) Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. Lab Invest 60: 275–285

    PubMed  CAS  Google Scholar 

  • Stout AP, Murray MR (1942) Hemangiopericytoma. A vascular tumor featering Zimmermanns’ pericytes. Ann Surg 116: 26–33

    Google Scholar 

  • Tomasek JJ, Schultz RJ, Haaksma CJ (1987) Extracellular matrix–cytoskeletal connections at the surface of the specialized contractile fibroblast (myofibroblast) in Dupuytren disease. J Bone Joint Surg [Am] 69: 1400–1407

    CAS  Google Scholar 

  • Ushijima M, Tsuneyoshi M, Enjoji M (1984) Dupuytren type fibromatoses. A clinicopathologic study of 62 cases. Acta Pathol Jpn 34: 991–1001

    PubMed  CAS  Google Scholar 

  • Viljanto JA (1973) Dupuytren’s contracture: a review. Semin Arthritis Rheum 3: 155–176

    Article  Google Scholar 

  • Vossbeck G (1986) Zur Pathogenese der Palmarfibromatose (Morbus Dupuytren) - autoradiographische und elektronenmikroskopische Untersuchung. Medical dissertation, University of Ulm

    Google Scholar 

  • Walker MA, Harley RA, Maize J, DeLustro F, LeRoy EC (1985) Mast cells and their degranulation in the Tsk mouse model of scleroderma. Proc Soc Exp Biol Med 180: 323–328

    PubMed  CAS  Google Scholar 

  • Walker MA, Harley RA, LeRoy EC (1987) Inhibition of fibrosis in Tsk mice by blocking mast cell degranulation. J Rheumatol 14: 299–301

    PubMed  CAS  Google Scholar 

  • Yost J, Winter T, Fett HC (1955) Dupuytrens contracture. A statistical study. Am J Surg 90: 568–571

    Google Scholar 

  • Zimmermann KW (1923) Der feinere Bau der Blutcapillaren. Z Anat Entwicklungsgesch 68: 29–109

    Article  Google Scholar 

Download references

Authors
  1. W. Mohr
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Wessinghage
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik für Plastische, Hand- und Wiederherstellungschirurgie, Krankenhaus Oststadt, Medizinische Hochschule Hannover, Podielskistraße 380, 30659, Hannover, Germany

    Alfred Berger  & Peter Brenner  & 

  2. Institut für Klinische Chemie II, Krankenhaus Oststadt, Medizinische Hochschule Hannover, Podbielskistraße 380, 30659, Hannover, Germany

    Axel Delbrück  & Rolf Hinzmann  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Mohr, W., Wessinghage, D. (1994). Morphology of Dupuytren’s Disease. In: Berger, A., Delbrück, A., Brenner, P., Hinzmann, R. (eds) Dupuytren’s Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78517-7_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-78517-7_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57239-8

  • Online ISBN: 978-3-642-78517-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation