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The Basic-Region Leucine-Zipper Family of DNA Binding Proteins

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Nucleic Acids and Molecular Biology

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 6))

Abstract

Related functions in proteins are commonly mediated by conserved structural motifs. Such motifs are widespread in transcriptional regulatory proteins. In this review, we will focus on the basic-region leucine-zipper or bZip motif, which is involved in dimerization and DNA recognition. Our emphasis will be on the relationship between the sequence and structure of the bZip motif, and the ways in which structural information relates to our understanding of the function of bZip proteins.

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Authors and Affiliations

  1. Department of Biochemistry and Biophysics, Texas A & M University, College Station, TX, 77843, USA

    J. C. Hu

  2. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA

    R. T. Sauer

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  1. J. C. Hu
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  2. R. T. Sauer
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Editors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Straße 3, W-3400, Göttingen, Germany

    Fritz Eckstein

  2. Biochemistry Department, University of Dundee, DD1 4HN, Dundee, UK

    David M. J. Lilley

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© 1992 Springer-Verlag Berlin Heidelberg

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Hu, J.C., Sauer, R.T. (1992). The Basic-Region Leucine-Zipper Family of DNA Binding Proteins. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77356-3_5

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  • DOI: https://doi.org/10.1007/978-3-642-77356-3_5

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  • Online ISBN: 978-3-642-77356-3

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