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Molecular and Cellular Biology of Shigella flexneri Invasiveness: From Cell Assay Systems to Shigellosis

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Pathogenesis of Shigellosis

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 180))

Abstract

Also known as bacillary dysentery, shigellosis, an invasive disease of the human colon, is present worldwide. It is of particular concern in tropical regions, especially in overcrowded areas of the developing world, where Shigella flexneri causes the endemic form of the disease and Shigella dyseriteriae 1 devastating epidemics. Children are the most common victims of this disease which is principally transmitted by the fecal-oral route in areas having inadequate hygiene and sanitation.

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  1. Unité de Pathogénie Microbienne Moléculaire, INSERM U199, Institut Pasteur, 28 Rue du Dr. Roux, 75724, Paris Cédex 15, France

    P. J. Sansonetti

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  1. Unité de Pathogénie Microbienne Moleculaire, Institut Pasteur, 28, Rue du Dr. Roux, 75724, Paris Cedex 15, France

    P. J. Sansonetti M.D

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© 1992 Springer-Verlag Berlin Heidelberg

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Sansonetti, P.J. (1992). Molecular and Cellular Biology of Shigella flexneri Invasiveness: From Cell Assay Systems to Shigellosis. In: Sansonetti, P.J. (eds) Pathogenesis of Shigellosis. Current Topics in Microbiology and Immunology, vol 180. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77238-2_1

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  • DOI: https://doi.org/10.1007/978-3-642-77238-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

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