Zusammenfassung
Veränderungen ereigniskorrelierter Hirnpotentiale (EKP), durch die sich schizophrene Patienten von psychisch gesunden Kontrollprobanden unterscheiden, wurden wiederholt beschrieben. Die P300-Amplitudenminderung bei Schizophrenen erwies sich dabei als besonders stabiles biologisches Phänomen (Olbrich 1989; Pritchard 1986). Dagegen sind die Befunde zur P300-Latenz, zur topographischen Verteilung und zur klinischen Relevanz der Veränderungen widersprüchlich.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Blackwood DH, Whalley LJ, Christie JE, Blackburn IM, St Clair DM, McInnes A (1987) Changes in auditory P3 event-related potential in schizophrenia and depression. Br J Psychiatry 150: 154–160
Brecher M, Porjesz B, Begleiter H (1987) Late positive component amplitude in schizophrenics and alcoholics in two different paradigms. Biol Psychiatry 22: 848–856
Crow TJ (1980) Molecular pathology of schizophrenia: more than one disease process? Br Med J 280: 66–68
Ebmeier KP, Potter DD, Cochrane RHB, MacKenzie AR, McAllister H, Besson JAO, Salzen EA (1990) P300 and smooth eye pursuit: concordance of abnormalities and relation to clinical features in DSM-III schizophrenia. Acta Psychiatr Scand 82: 283–288
Faux SF, Torello MW, McCarley RW, Shenton ME, Duffy FH (1988) P300 in schizophrenia: Confirmation and statistical validation of temporal region deficit in P300 topography. Biol Psychiatry 23: 776–790
Goodin DS, Starr A, Chippendale T, Squieres KC (1983) Sequential changes in the P3 component of the auditory evoked potential in confusional states and dementing illnesses. Neurology 33: 1215–1218
Maurer K, Dierks T (1988) Topographie der P300 in der Psychiatrie — I. Kognitive P300-Felder bei Psychosen. Z EEG EMG 18: 21–25
Olbrich HM (1989) Ereigniskorrelierte Potentiale. In: Stöhr M, Dichgans J, Diener HC, Buettner UW (Hrsg) Evozierte Potentiale. Springer, Berlin Heidelberg New York Tokyo, S 513–587
Pfefferbaum A, Wenegrat BG, Ford JM, Roth WT, Kopell BS (1984) Clinical application of the P3 component of event-related potentials. II. Dementia, depression and schizophrenia. Electroencephalogr Clin Neurophysiol 59: 104–124
Pfefferbaum A, Ford JM, White PM, Roth WT (1989) P3 in schizophrenia is affected by stimulus modality, response requirements, medication status, and negative symptoms. Arch Gen Psychiatry 46: 1035–1044
Pritchard WS (1986) Cognitive event-related potential correlates of schizophrenia. Psychol Bull 89: 43–66
Shenton ME, Faux SF, McCarley RW, Ballinger R, Coleman M, Torello M, Duffy FH (1989) Correlations between abnormal auditory P300 topography and positive symptoms in schizophrenia: a preliminary report. Biol Psychiatry 25: 710–716
Strick WK, Dierks T, Müller T, Maurer K (1991) Cognitive components of auditory evoked potentials in schizophrenic disorders: Topography and clinical correlations. In: Maurer K (ed) Imaging of the brain in psychiatry and related fields. Springer, Berlin Heidelberg New York Tokyo
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Eikmeier, G., Olbrich, H.M., Lodemann, E., Zerbin, D., Unger, C., Gastpar, M. (1992). P300 und schizophrene Negativsymptomatik. In: Gaebel, W., Laux, G. (eds) Biologische Psychiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77086-9_51
Download citation
DOI: https://doi.org/10.1007/978-3-642-77086-9_51
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-54784-6
Online ISBN: 978-3-642-77086-9
eBook Packages: Springer Book Archive