Zusammenfassung
Die Herkunft von Zellen des Monozyten-/Makrophagensystems (MMS) aus dem Knochenmark ist durch zahlreiche Untersuchungen gesichert [44, 64, 95 u. a.]. Da Makrophagen ihre Funktion in engem Zusammenwirken mit anderen Blutzellen (Lymphozyten, Zellen der Myelopoese u. a.) erfüllen, begleiten Veränderungen des Blutbildes sowie immunologische Abweichungen häufig Erkrankungen des Makrophagensystems.
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Literatur
Babior BM (1988) Function of Neutrophils and Mononuclear Phagocytes; Disorders of Neutrophil Function. In: Cecil Textbook of Medicine, Saunders
Barrow MV, Holubar K (1969) Multicentric reticulohistiocytosis. A review of 33 patients. Medicine 48:287–305
Barth J, Kreipe H, Kiemle-Kalle J, Radzun HJ, Parwaresch MR, Petermann W (1988) Diminished activity of tartrate-resistant acid phosphatase in alveolar macrophages from patients with active sarcoidosis. Thorax 43:901–904
Beckstead JH. Wood GS, Turner RR (1984) Histiocytosis X cells and Langerhans cells. Enzyme histochemical and immunologic similarities. Hum Pathol 15:826–833
Besley GTN, Moss SE (1983) Studies on sphingomyelinase and β-glucosidase activities in Niemann-Pick disease variants. Phosphodiesterase activities measured with natural and artificial substrates. Biochem Biophys Acta 752:54
Beutler B et al (1986) Control of cachectin (Tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. Science 232:977
Bjerkens R, Laerum OD, Odegaard S (1985) Impaired bacterial degradation by monocytes and macrophages from a patient with Whipple’s disease. Gastroenterology 89: 1139–1146
Blattner RJ (1964) Generalized BCG infection. J Pediatr 65:311–314
Brady RO (1983) Sphingomyelin lipidosis: Niemann-Pick disease. In: Stanbury JB, Wyngaarden JB, Fredrickson DS et al (eds) The Metabolic Basis of Inherited Disease, 5th ed. McGraw-Hill Book Company, New York
Burgess A W, Metcalf D (1980) The nature and action of granulocyte-macrophage colony stimulating factors. Blood 56:947–958
Caputo R, Gianotti F (1980) Cytoplasmic markers and ultrastructural features in histiocytic proliferations of the skin. J Ital Dermatol Venerol 115: 107–120
Carbone A, Poletti A, Mancone R, Volpe R, Sanzi C (1985) Demonstration of S-100 protein distribution in human lymphoid tissues by the avidin-biotin complex immunostaining method. Hum Pathol 16: 1157–1167
Catovsky D, O’Brien M (1981) Lysosomal granules in leukemic monocytes and their relation to maturation stages. In: Schmalzl F, Huhn D, Schaefer HE (eds) Disorders of the monocyte macrophage system. Springer, Berlin Heidelberg New York, p 167
Celada A, Allen R, Esparza I, Gray PW, Schreiber RD (1985) Demonstration and Partial Characterization of the Interferon-Gamma Receptor on Human Mononuclear Phagocytes. J Clin Invest 76:2196–2205
Chu T, D’Angio GJ, Favara B et al (1987) Histiocytosis syndromes in children. Lancet 1: 208
Coode PE, Ridgway H, Jones DB (1980) Multicentric retriculohistiocytosis: Report of two cases with ultrastructural, tissue culture and immunologic studies. Clin Exp DermatoI5:281–293
Dawson PJ, Dawson G (1982) Adult Niemann-Pick disease with sea-blue histiocytes in the spleen. Hum Pathol13:1115
Dehner LP (1991) Morphologic findings in the histiocytic syndromes. Semin Oncol 18:8–17
Dewhurst N et al (1979) Sea blue histiocytosis in a patient with chronic non-neuropathic Niemann-Pick disease. J Clin Pathol 32: 1121
Dinarello CA (1991) Interleukin-l and interleukin-1 antagonism. Blood 77:1627–1652.
Dustin ML, Staunton DE, Springer TA (1988) Supergene families meet in the immune system. Immunol Today 9:213–215
Enrique P, Dahlin DC, Hayles AB, Henderson ED (1967) Histiocytosis X: a clinical study. Mayo Clin Proc 42:88–99
Fanburg B (1988) Sarcoidosis. In: Cecil Textbook of Medicine, Saunders
Farquhar JW, Claireaux AF (1952) Familial hemophagocytic reticulosis. Arch Dis Child 27:519–525
Fauchier C, Benatre A, Regy JM, Jobard P, Combe P (1970) La Iymphohistiocytose familiale. Arch Fr Pediatr 27:51
Fithian E, Kung P, Goldstein G, Rubenfeld M, Fenoglio C, Edelson R (1981) Reactivity of Langerhans cells with hybridoma antibody. Proc Natl Acad Sci USA 78:2541–2544
Galili U, Rachmilewitz EA, Peleg A, Flechner I (1984) A unique natural human IgG antibody with anti-alpha-galactosyl specifity. J Exp Med 160:1519–1531
Gadner H, Heitger A, Ritter J et al (1987) Langerhanszell-Histiozytose im Kindesalter - Ergebnisse der DAL-HX83 Studie. Klin Plidiat 199: 173–182
Gerdes J, Stein H, Mason DY, Ziegler A (1983) Human dendritic reticulum cells of lymphoid follicles: their antigenic profile and their identification as multinucleated giant cells. Virchows Arch (Cell Pathol) 42: 161–172
Gibbs AR, Williams WJ (1986) The pathology of sarcoidosis. Sem Resp Med 8:10–16
Groh V, Gadner H, Radaskiewicz T et al (1988) The phenotypic spectrum of histiocytosis X cells. J Invest Dermatol 90:441–447
Groopman JE (1988) Langerhans cell (eosinophilic) granulomatosis. In: Cecil Textbook of Medicine, Saunders
Groopman JE, Golde DW (1981) The histiocytic disorders: a pathophysiologic analysis. Ann Int Med 94:95–107
Haas RJ, Helmig MSE, Meister P (1981) Sinus histiocytosis with massive lymphadenopathy and epidural involvement. In: Schmalzl F, Huhn D, Schaefer HE (eds) Disorders of the monocyte macrophage system. Springer, Berlin Heidelberg New York, p 239
Henter JI, Elinder G, Oest A et al (1991) Diagnostic guidelines for hemophagocytic Iymphohistiocytosis. Semin Oncol 18:29–33
Herlin T, Pallesen G, Kristensen T, Clausen N (1987) Unusual immunophenotype displayed by histiocytes in hemophagocytic lymphohistiocytosis. J Clin Pathol 40:1413–1417
Histiocyte Society Writing Group (1987) Histiocytosis syndromes in children. Lancet 1:208–209
Hoefsmit ECM et al (1982) Langerhans cells, veiled cells, and interdigitating cells. Immunobiology 161:255
Hogg N (1989) Surface molecules and receptors. In: Asherson GL, Zembala M (eds) Human monocytes. Academic Press, London
Huber H, Fudenberg HH (1968) Receptor sites of human monocytes for IgG. Int Arch Allergy 34: 18
Huhn D, Meister P (1978) Malignant histiocytosis. Morphology and cytochemical findings. Cancer 42: 1341
Jandl JH (1987) Blood Textbook of Hematology. Little, Brown and Company Bostonfforonto
Janka GE (1983) Familial hemophagocytic lymphohistiocytosis. Eur J Pediatr 140:221–230
Johnston RB (1983) Monocytes and macrophages. N Engl J Med 318:747–752
Kaiserling E, Lennert K, Nitsch K, Drescher J (1972) Ultrastruktur und Pathogenesem der BCG-Histiocytose (sog. BCG-Granulomatose). Virchows Arch (Pathol Anat) 355:333–353
Klein J (1991) Immunologie. In: Schmidt RE (Hrsg). VCH Verlagsgesellschaft, Weinheim
Knapp W (1989) Leucocyte typing IV. Oxford Univ Press, Oxford
Kolodny EH (1988) Gaucher’s Disease; Niemann-Pick Disease. In: Cecil Textbook of Medicine, Saunders Company
Komp DM (1987) Langerhans cell histiocytosis. N Engl J Med 316:747
Komp DM, Perry MC (1991) Introduction: the histiocytic syndromes. Semin Oncol 18:1–2
Kreipe H, Radzun HJ, Parwaresch MR, Hansmann ML (1987) Ki-M7 monoclonal antibody specific for myelomonocytic cell lineage and macrophages in human. J Histochem Cytochem 35:1117–1126
Lahey E (1975) Histiocytosis X: An analysis of prognostic factors. J Pediatr 87:184–189
Lampert JA, Catovsky D, Bergier N (1978) Malignant histiocytosis: A clinico-pathological study of 12 cases. Br J Haematol 40:65.
Lasser A (1983) The mononuclear phagocytic system. A review. Hum Pathol 14:108–126
Leder LD (1967) Der Blutmonozyt. Springer, Berlin
Lennert K in collaboration with Mohri N, Stein H, Kaiserling E, Müller-Hermelink HK (1978) Malignant lymphomas other than Hodgkin’s disease. Springer Verlag, Berlin Heidelberg New York
Lichtenstein L (1953) Histiocytosis X. Integrating of eosinophilic granuloma of bone, “Letterer-Siwe-disease” and “Schüller-Christian disease” as related manifestations of a single nosologic entity. Arch Pathol 56: 84–102
Lichtenstein L (1964) Histiocytosis X (eosinophilic granuloma of bone, Letterer-Siwe disease, Hand-Schüller-Christian’s disease). J Bone Joint Surg 46:76–90
Loutit JF, Nisbet NW (1982) The origin of osteoclasts. Immunobiology 161:193
Low PS, Waugh SM (1985) The Role of Hemoglobin Denaturation and Band 3 Clustering in Red Blood Cell Aging. Science 227:531–533
Loy TS, Diaz-Arias AA, Perry MC (1991) Familial erythrophagocytic lymphohistiocytosis. Semin Oncology 18:34–39
Mackaness GB (1962) Cellular resistance to infection. J Exp Med 116:381–406
Mann RB, Jaffe ES, Berard CW (1979) Malignant lymphomas - a conceptual understanding of morphologic diversity. Am J Pathol 9411: 105
Manoharan A, Catovsky D (1981) Histiocytic medullary reticulosis re-visited. In: Schmalzl F, Huhn D, Schaefer HE (eds) Disorders of the monocyte macrophage system. Springer, Berlin Heidelberg New York, p 205
Markey GM, Alexander HD, McConnel R. Kyle A, Morris TCM, Robertson JH (1986) Hereditary monocyte esterase deficiency. Brit J Haematol 63:359–362
Martinet Y, Bittermann PB, Mornex JF, Grotendorst GR. Martin GR, Crystal RG (1986) Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like acitivity. Nature 319: 158–160
Meuret G et al (1975) Monocytopoiesis in normal man: Pool size, proliferation activity and DNA synthesis time of promonocytes. Acta Haematol 54:261
Monda L, Warnke R, Rosai J (1986) A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation. A report of 4 cases. Am J Pathol 122:526–572
Morahan PS (1980) Macrophage nomenclature: Where are we going? J Reticuloendothel Soc 27:223–245
Morgan R, Hecht BK, Sandberg AA, Hecht F (1986) Chromosome 5q35 breakpoint in malignant histiocytosis. N Engl J Med 314:1322
Mrozek EC, Weisenburger DD, Lipscomb Grierson H, Markin R, Purtilo DT (1987) Fatal infectious mononucleosis and virusassociated hemophagocytic syndrome. Arch Pathol Lab Med 111: 530–535
Naiem N. Gerdes JU. Abdulaziz Z. Stein H, Mason DY (1983) Production of a monoclonal antibody reactive with human dendritic reticulum cells and its use in the immunohistological analysis of lymphoid tissue. J Clin Pathol 36:167–175
Nezelof C, Frileux-Herbert F, Cronier-Sachot J (1979) Disseminated histiocytosis X: Analysis of prognostic factors based in a retrospective study of 50 cases. Cancer 44:1824–1838
Nimer SD, Golde DW (1987) The 5q-abnormality. Blood 70:1705–1712
Pallesen G, Myhre-Jensen O (1987) Immunophenotypic analysis of neoplastic cells in follicular dendritic cell sarcoma. Leukemia 1:549–557
Parwaresch MR. Wacker HH (1984) Origin and kinetics of resident tissue macrophages, Parabiosis studies with radiolabelled leukocytes. Cell Tiss Kinet 17:25–39
Parwaresch MR. Radzun HJ. Feller AC, Peters KP, Hansmann ML (1983) Peroxidase- positive mononuclear leukocytes as possible precursors of human dendritic reticulum cells. J Immunol 131:2719–2725
Parwaresch MR, Horny HP. Lennert K (1985) Tissue mast cells in health and disease. Path Res Pract 179:439–461
Pasyk KA. Grabb WC, Cherry GW (1983) Ultrastructure of mast cells in growing and involuting stages of hemangiomas. Hum Pathol 14:174–181
Pentchev PG, Comly ME, Kruth HS et al (1985) A defect in cholesterol esterification in certain patients designated as Niemann-Pick disease type C. Proc Natl Acad Sci USA 82:8247
Qualman SJ, Gupta PK. Mendelsohn G (1984) Intracellular Escherichia coli in urinary malakoplakia. A reservoir of infection and its therapeutic implications. Am J Clin Pat hoi 81: 35–42
Radzun HJ, Kreipe H, Bodewadt S, Hansmann ML, Barth J, Parwaresch MR (1987) Ki-M8 monoclonal antibody reactive with an intracytoplasmic antigen of monocyte/ macrophage lineage. Blood 69: 1320–1327
Radzun HJ, Kreipe H, Heidorn K, Parwaresch MR (1988a) Modulation of c-fms protooncogene expression in human blood monocytes and macrophages. J Leukocyte Bioi 44:198–204
Radzun HJ, Kreipe H, Zavazava N, Hansmann ML, Parwaresch MR (1988b) Diversity of the human monocyte/macrophage system as detected by monoclonal antibodies. J Leukocyte Bioi 43:41–50
Ralfkiaer E, Stein H. Plesner T, Hou-Jensen K, Mason D (1984) In situ immunological characterization of Langerhans cells with monoclonal antibodies: comparison with other dendritic cells in skin and lymph nodes. Virchows Arch (Pathol Anat) 403: 401–402
Risdall RJ, McKenna RW. Nesbit ME, Krivitt W, Balfour HH, Simmons RC, Brunning RD (1979) Virus-associated hemophagocytic syndrome. A benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44:993–1002
Rosai J, Dorfman RF (1972) Sinus histiocytosis with massive lymphadenopathy: A pseudolymphomatous benign disorder. Analysis of 34 cases. Cancer 30: 1174–1188
Rosenthal AS (1980) Regulation of the immune response - role of the macrophage. N Engl J Med 303: 1153–1156
Rosenthal DI, Scott JA, Barranger J et al (1986) Evaluation of Gaucher disease using magnetic resonance imaging. J Bone Joint Surg 68:802
Ruddle NH (1987) Tumor necrosis factor and related cytotoxins. Immunol Today 8: 129–130
Sanchez-Madrid F, Nagy JA, Robbins E, Simon P, Springer TA (1983) A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: The lymphocyte functions-associated antigen (LFA-1), the C3bi complement receptor (OKMlIMaxc-1), and the p150,95 molecule. J Exp Med 158:1785–1803
Sariban E, Mitchell T, Kufe D (1985) Expression of c-fms protooncogene during human monocytic differentiation. Nature 314:64–66
Sawitzky A, Rosner F, Chodsky S (1972) The sea-blue histiocyte syndrome, a review: Genetic and biochemical studies. Semin Hematol 9:285
Schaefer HE (1981) The role of macrophages in storage diseases. In: Schmalzl F, Huhn D, Schaefer HE (eds) Disorders of the monocyte macrophage system. Springer, Berlin Heidelberg New York, p 121
Schmalzl F, Braunsteiner H (1967) Zytochemische Untersuchungen zur Entwicklung der großen mononuklearen Zellen des Hautfensters. Acta Haematol 39:281–291
Scott RB, Robb-Smith ANT (1939) Histiocytic medullary reticulosis. Lancet II: 194–198
Shamato M (1970) Langerhans’ cell granuloma in Letterer-Siwe disease. Cancer 26: 1102–1108
Sherr CJ, Rettenmeier CW, Sacca R, Roussel MF, Look AT, Stanley ER (1985) The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-l. Cell 41:665–676
Sims DC (1977) Histiocytosis X: Follow-up of 43 Cases. Arch Dis Child 52:433
Snyderman R, Pike MC (1976) An inhibitor of macrophage chemotaxis produced by neoplasmas. Science 192:370–372
Sonneveld P, van Lomk, Kappersklunne M et al (1990) Clinicopathological diagnosis and treatment of malignant histiocytosis. Br J Haematol 75:511–516
Springer TA, Thompson WS, Miller LJ, Schmalstieg FC, Anderson DC (1984) Inherited deficiency of the Mac-I, LFA-1, P 150,95 glycoprotein family and its molecularbasis. J Exp Med 160:1901–1918
Spry CIF et al (1980) Large mononuclear (veiled) cell-like “la-like” membrane antigens in human afferent lymph. Clin Exp Immunol 39:750
Stein H, Gerdes J, Mason DY (1982) The normal and malignant germinal centre. Clin Haematol 11:531:559
Stein H, Dienemann D, Dallenbach F, Kruschwitz M (1991) Peripheral T-cell lymphomas. Ann Oncol 2:Suppl 2, 163–169
Steinmann RM, Cohn ZA (1975) Dendritic cells, reticular cells, and macrophages. In: van Furth R (eds) Mononuclear Phagocytes in Immunity, Infection and Pathology. Blackwell Scientific Publications, Oxford
Tew JG, Thorbecke GJ, Steinmann RM (1982) Dendritic cells in the immune response: Characteristics and recommended nomenclature (A report from the Reticuloendothelial Society Committee in Nomenclature). J Reticuloendothel Soc 31:371–380
Tsuji S, Martin M, Barranger JA et al (1988) Genetic heterogeneity in type I Gaucher disease. PNAS 85:2349–2352
Unanue ER (1976) Secretory function of mononuclear phagocytes: A review. Am J Pathol 83:396–417
Van Furth R, Cohn ZA (1968) The origin and kinetics of mononuclear phagocytes. J Exp Med 128:415–433
Vardiman JW, Byrne GE, Rappaport H (1975) Malignant histiocytosis with massive splenomegaly in asymptomatic patients. Cancer 36:419–427
Venet A, Hance AJ, Saltini C, Robinson BWS, Crystal RG (1985) Enhanced alveolar macrophage-mediated antigen induced T lymphocyte proliferation in sarcoidosis. J Clin Inest 75:293–301
Warnke RA, Kim H, Dorman RF (1975) Malignant histiocytosis (histiocytic medullary reticulosis) I. Clinicpathologic study of 29 cases. Cancer 35:215–230
Wheeler MS, Wilson EC, Stass SA (1981) Erythroleucophagocytosis by leukemic cells - a nonspecific finding. Am J Clin Pathol 75:266–267
Williams GT, Williams WJ (1983) Granulomatous inflammation: A review. J Clin Pathol 36:723
Winkelmann RK (1981) Cutaneous syndromes of non-X histiocytosis: A review of the macrophage-histiocyte disease of the skin. Arch Dermatol 117:667–672
Winkelmann RK, Hu Ch, Kossard S (1982) Response of nodular non-X histiocytosis to vinblastin. Arch Dermatol 118:913–917
Wolfson SL, Botero F, Hurwitz S, Pearson HA (1981) “Pure” cutaneous histiocytosis x. Cancer 48:2236–2238
Wood GS, Turner RR, Shiurba RA, Eng L, Warnke RA (1985) Human dendritic cells and macrophages: In situ immunophenotypic definition of subsets that exhibit specific morphologic and microenvironmental characteristics. Am J Pathol 119:73–82
Zinkham WH (1976) Multifocal eosinophilic granuloma: Natural history, etiology and management. Am J Med 60:457
Zimran A, Sorge J, Gross E et al (1990) A glucocerebrosidase fusion gene in Gaucher disease. J Clin Invest 85:219–222
Zimran A, Gross E, West C et al (1989) Prediction of severity of Gaucher’s disease by identification of mutations at DNA level. Lancet 2:349–352
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Parwaresch, M.R., Radzun, H.J., Nachbaur, D., Pastner, D., Huber, H. (1992). Erkrankungen des Monozyten-/Makrophagensystems. In: Huber, H., Löffler, H., Pastner, D. (eds) Diagnostische Hämatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-76860-6_18
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