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Structure and Function of High Endothelial Postcapillary Venules in Lymphocyte Circulation

  • Chapter
Reaction Patterns of the Lymph Node

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 84/1))

Abstract

The interdependence of the tissue and organ components that constitute the immune system is maintained and controlled by continuous interorgan lymphocyte traffic via the circulation. This lymphocyte traffic is accompanied by differentiations of lymphocytes into lymphocytes with different qualities of immunocompetency and in this way determines the immune responses of the tissues and organs involved. This interorgan traffic is clearly not a random event. Specific and selective factors determine its high degree of organization. In their movement from one anatomical site to another, the lymphocytes cross endothelial barriers. The specificities involved in the interaction between lymphocytes and the endothelia concerned and which result in the selective lymphocyte transmural passage are the essential regulatory factors in the interorgan traffic of lymphocytes.

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Authors
  1. P. P. H. De Bruyn
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  2. Y. Cho
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Editor information

Editors and Affiliations

  1. Gerhard-Domagk-Institut für Pathologie, der Universität Münster, Domagkstr. 17, 4400, Münster, Federal Republic of Germany

    E. Grundmann (Professor Dr.) & E. Vollmer (Dr. Dr.) (Professor Dr.) &  (Dr. Dr.)

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© 1990 Springer-Verlag Berlin Heidelberg

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De Bruyn, P.P.H., Cho, Y. (1990). Structure and Function of High Endothelial Postcapillary Venules in Lymphocyte Circulation. In: Grundmann, E., Vollmer, E. (eds) Reaction Patterns of the Lymph Node. Current Topics in Pathology, vol 84/1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75519-4_4

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  • DOI: https://doi.org/10.1007/978-3-642-75519-4_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75521-7

  • Online ISBN: 978-3-642-75519-4

  • eBook Packages: Springer Book Archive

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