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Forschungsinstrumente zur Erfassung der Lebensqualität bei Krebs — ein Überblick

  • Chapter
Psychosoziale Onkologie

Part of the book series: Jahrbuch der medizinischen Psychologie ((MEDPSYCHOL,volume 3))

Zusammenfassung

Die zunehmende Anerkennung psychosozialer Aspekte der Krebsbehandlung hat zur Entwicklung einer Reihe von Ansätzen zur Erfassung der Lebensqualität in Therapiestudien geführt. Diese Ansätze beinhalten Fragebögen zur Einschätzung der Lebensqualität und ihrer Komponenten (körperliche Verfassung, psychisches Wohlbefinden, soziale Beziehungen und Funktionsfähigkeit im Alltag) durch Patienten und medizinisches Personal.

Auf der Grundlage konzeptueller, methodischer und praktischer Kriterien wird die Eignung dieser Meßinstrumente für die Therapieforschung diskutiert, mit speziellem Bezug zur Übersetzung und Testung der Skalen für deutschsprachige Patienten. Zur Auswahl von Skalen für spezifische Studienzwecke werden Empfehlungen, und für weitere zu bearbeitende Problembereiche werden Hinweise gegeben.

Summary

The increasing recognition of psychosocial aspects of cancer treatment has resulted in multiple approaches to measuring quality of life in therapeutic studies. These approaches include checklists and questionnaires based on physician and patient ratings of global quality of life and its components, i.e. physical state, psychological well-being, social relationships and functions of every day life. Available instruments range from general assessments of quality of life across diseases to cancer-specific approaches.

Based on conceptual, methodological and practical criteria, the appropriateness of these instruments for research purposes is discussed with special reference to their translation and testing for use with German-speaking patients. Recommendations for the selection of scales for specific study purposes are given, and problem areas requiring further investigation are identified.

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Literatur

  • Aaronson NK (1986) Methodological issues in psychosocial oncology with special reference to clinical trials. In: Ventafridda V, Dam FSAM van, Yancik R, Tamburini M (eds) Assessment of quality of life and cancer treatment. Excerpta Medica, Amsterdam, pp 29–41

    Google Scholar 

  • Aaronson NK, Beckman J (1987) Quality of life of cancer patients. Raven, New York

    Google Scholar 

  • Aaronson NK, Bakker W, Stewart AL, Dam FSAM van, Zandwijk N van, Yarnold JR, Kirkpatrick A (1987) Multidimensional approach to the measurement of quality of life in lung cancer clinical trials. In: Aaronson NC, Beckman J (eds) The quality of life of cancer patients. Raven, New York, pp 63–82

    Google Scholar 

  • Aaronson NK, Bullinger M, Ahmedzai S (1988) A modular approach to quality of life in cancer clinical trials. Springer, Berlin Heidelberg New York Tokyo (Recent results in cancer research, vol 111)

    Google Scholar 

  • Badura P, Waltz M (1987) Leben mit dem Herzinfarkt. Springer, Berlin Heidelberg New York Tokyo

    Book  Google Scholar 

  • Bergner M, Bobbit RA, Carter WB, Gilson BS (1981) The sickness impact profile development and final revision of a health status measure. Med Care 19:787–805

    Article  PubMed  CAS  Google Scholar 

  • Bernheim J, Avonts G, de Schampheleire D, Gelissen I, Sauer AM (1985) Anamnestic comparative self assessment (ACSA) to correlate medical and psychosocial variables with subjective quality of life of cancer patients. Proc Am Soc Clin Oncol 4:248

    Google Scholar 

  • Biefang S (1985) Messung psychosozialer Erfolgs- und Prädiktorvariablen. Habilitationsschrift, Universität Ulm

    Google Scholar 

  • Bradburn N (1969) The structure of psychological well-being. Aldine, Chicago

    Google Scholar 

  • Bullinger M, Hasford J (im Druck) Testing and evaluating quality of life measures for German clinical trials. Controlled clinical trials,

    Google Scholar 

  • Bullinger M, Pöppel E (1988) Lebensqualität in der Medizin: Schlagwort oder Forschungsansatz. Dtsch Ärztebl 85:679–680

    Google Scholar 

  • Bullinger M, Heinisch M, Ludwig M, Geier S (in Druck a) Studien zur Erfassung des Wohlbefindens — psychometrische Analysen zum Profil von Mood States (POMS) und zum Psychological General Well-Being Index (PGWBI). Z Diff Diagn Psychol

    Google Scholar 

  • Bullinger M, and the Quality of Life Study Group (in Druck b) Quality of life research in West-Germany — the Munich experience. In: Shuhmaker S, Fruberg C, Czajkowski S, Schron E (eds) Quality of life and cardiovascular disease, Springer, New York

    Google Scholar 

  • Caiman KC (1987) Definitions and dimensions of quality of life. In: Aaronson NK, Beckman JG, Bernheim JL, Zittoun R (eds) The quality of life of cancer patients. Raven, New York, pp 1–10

    Google Scholar 

  • Ciampi A, Silberfeld M, Till JE (1983) Health status indices: Some approaches and their limitations for oncology. Inter Psychol 15:4–14

    Google Scholar 

  • Clark A, Fallowfield LJ (1986) Quality of life measurements in patients with malignant disease a review. J R Soc Med 79:165–169

    PubMed  CAS  Google Scholar 

  • Coates A, Dillenbeck CF, McNeil R et al. (1983) On the receibing end -II. Linear analogue self-assessment (LASA) in evaluation of aspects of the quality of life cancer patients receibing therapy. Eur J Cancer Clin Oncol 19:1633–1637

    Article  PubMed  CAS  Google Scholar 

  • Dam FSAM van, Aaronson N (1987) Practical problems in conducting cancer psychosocial research, n: Aaronson N, Beckman J (eds) The quality of life of cancer patients. Raven, New York, pp 111–119

    Google Scholar 

  • Dam FSAM van, Linssen CA, Couzijn AL (1984) Evaluating quality of life in cancer clinical trials. In: Buyse ME, Staanet MJ, Sybester RJ (eds) Cancer clinical trails. Methods and practice. Oxford University Press, New York

    Google Scholar 

  • Dean H (1985) Choosing multiple instruments to mesure the quality of life. Oncol Nurs Forum 12 5:96–100

    PubMed  CAS  Google Scholar 

  • De Haes JCJM, Knippenberg FCE von (1987) Quality of life of cancer patients. Review of literature. In: Aaronson NK, Beckmann JH (eds) The quality of life of cancer patients. Raven, New York, pp 167–183

    Google Scholar 

  • De Haes JCJM, Osterom MA van, Welvaeert K (1986) The effect of radical mastectomy and conserving surgery on the quality of life of early breast cancer patients. Eur J Oncol 12:337–342

    Google Scholar 

  • Deyo RA, Inui TS (1984) Toward clinical applications of health status measures: sensitivity of scales to clinically important changes. Health Serv Res 19 3:275–289

    PubMed  CAS  Google Scholar 

  • Diener E (1984) Subjective well-being. Psychol Bull 95 3:542–575

    Article  PubMed  CAS  Google Scholar 

  • DuPuy HJ (1984) The Psychological General Weil-Being (PGWB) Index. In: Wenger NK, Mattson ME, Furberg CD, Ellinson J (eds) Assessment of quality of life in clinical trials of cardiovascular therapies. LeJacq, New York, pp 170–183

    Google Scholar 

  • Fahrenberg J, Myrtek M, Wilk D, Kreutel K (1986) Multimodale Erfassung der Lebenszufriedenheit: Eine Untersuchung and Herz-Kreislauf-Patienten. Psychother Med Psychol 36 11:347–354

    CAS  Google Scholar 

  • Flechter AE, Hunt BM, Bulpitt CJ (1987) Evaluation of quality of life in clinical trials of cardiovascular disease. J Chronic Dis 40:557–566

    Article  Google Scholar 

  • Frank-Stromborg M (1984) Selecting an instrument to measure quality of life. Oncol Nurs Forum 11:88–91

    PubMed  CAS  Google Scholar 

  • Furberg CD (1985) Assessment of quality of life. In: Friedman L, Furberg C, Demets D (eds) Fundamen tals of clinical trials. PSG Publishing Co, Littletown, pp 161–170

    Google Scholar 

  • Ganz P, Haskell CH, Figglin R (1988) Estimating the quality of life in a clinical trial of patients with metastatic lung cancer using the Karnowsky Performance Index and the Functional Living Index Cancer (FLIC). Cancer 61:849–856

    Article  PubMed  CAS  Google Scholar 

  • Greenwald PHD (1987) The specificity of quality-of-life measures among the seriously ill. Med Care 25:642–651

    Article  PubMed  CAS  Google Scholar 

  • Greer S (1984) The psychological dimension in cancer treatment. Soc Sci Med 18 4:345–349

    Article  PubMed  CAS  Google Scholar 

  • Guyatt GH (1987) Measuring quality of life. A review of means of measurement in clinical trials of new medicines. Pharm Med 2:49–60

    Google Scholar 

  • Guyatt GH, Bombarier C, Tugwell PX (1986) Measuring disease-specific quality of life in clinical trials, Can Med Assoc J 134:889–895

    CAS  Google Scholar 

  • Guyatt G, Walter S, Norman G (1987) Measuring change over time: Assessing the usefullness of evaluative instruments. J Chronic Dis 40:171–178

    Article  PubMed  CAS  Google Scholar 

  • Holland JC, Bahna G, McKegney P, Silberfarb P, Tross S, Glidewell O (1980) Psychiatric research in multimodal cancer clinical trials in CALGB (Meeting abstract). Proc Am Assoc Cancer Res 21:354

    Google Scholar 

  • Hunt S (1988) Measuring health in clinical care and clinical trials. In: Teeling-Smith G (ed) Measuring health — a practical approach. Wiley, Chicester, pp 7–23

    Google Scholar 

  • Hürny C, Bernhard J (1986) Methodische Probleme bei der Messung von Lebensqualität bei Krebskranken in klinischen Studien. Schweiz Rundsch Med Prax 75 28:845–846

    PubMed  Google Scholar 

  • Hutchinson TA, Boyd NF, Feinstein AR (1979) Scientific problems in clinical scales as demonstrated in the Karnofsky index of performance status. J Chronic Dis 32:661–666

    Article  PubMed  CAS  Google Scholar 

  • Jones DR, Fayers PM, Simons J (1987) Measuring and analyzing quality of life in cancer clinical trials: A review. In: Aaaronson NK, Beckman JH, Bernheim JL, Zittoun R (eds) The quality of life of cancer patients. Raven, New York, pp 41–62

    Google Scholar 

  • Kaplan RM, Bush JW, Berry CC (1976) Helath status: types of validity and the index of well-being. Health Serv Res 11:478–507

    PubMed  CAS  Google Scholar 

  • Karnofsky DA, Burchenal JH (1949) The clinical evaluation of chemotherapeutic agents in cancer. In: MacLeod CM (ed) Evaluation of chemotherapeutic agents. Columbia University Press, New York

    Google Scholar 

  • Katz S (1987) The science of quality of life. J Chronic Dis 40:459–463

    Article  PubMed  CAS  Google Scholar 

  • Kirshner B, Guyatt G (1985) A methodological framework for assessing health indices. J Chronic Dis 38:27–36

    Article  PubMed  CAS  Google Scholar 

  • Lane DA (1987) Utility, decision, and quality of life. J Chronic Dis 40 6:585–591

    Article  PubMed  CAS  Google Scholar 

  • Levine S, Croog SH (1984) What constitutes quality of life? A conceptualization of the dimensions of life quality in healthy populations and patients with cardiovascular disease. In: Wenger NK, Mattson ME, Furberg CD, Ellison J (eds) Assessment of quality of life in clinical trials of cardiovascular therapies. LeJacq, New York, pp 46–66

    Google Scholar 

  • MacKenzie CR, Charlson MG, Di Gioia D, Velley V (1986) Can the sickness impact profile measure change? An example of scale assessment. J Chronic Dis 39 6:429–438

    Article  PubMed  CAS  Google Scholar 

  • Margolese RG (1987) The place of psychosocial studies in medicine and surgery. J Chronic Dis 40:627–628

    Article  PubMed  CAS  Google Scholar 

  • McDowell I, Newell C (1987) Measuring health: A guide to rating scales and questionnaires. Oxford University Press, New York

    Google Scholar 

  • McNair D, Lorr M, Droppleman LF (1971) EITS manual for the profile of mood states. Educational and Industrial Testing Service, San Diego/CA

    Google Scholar 

  • Miller AB, Hoogstraaten B, Staquet M, Winkler A (1981) Reporting results of cancer treatment. Cancer 47:207–214

    Article  PubMed  CAS  Google Scholar 

  • Muthny FA, Koch U, Spaete M (1986) Psychosoziale Auswirkungen der Mastektomie und Bedarf an psychosozialer Versorgung — eine empirische Untersuchung mit Mammakarzinom-patientinnen. Psychother Med Psychol 36:240–249

    CAS  Google Scholar 

  • Najman JM, Levine S (1981) Evaluating the impact of medical care and technology on the quality of life. A review and critique. Soc Sci Med 15F: 107–115

    PubMed  Google Scholar 

  • Olschewski M (1985) Möglichkeiten der Evaluierung und Analyse von Lebensqualität im Rahmen klinischer Studien. EDV Med Biol 16:8–16

    Google Scholar 

  • Orr ST, Aisner J (1986) Performance status assessment among oncology patients: a review. Cancer Treat Rep 70 12:1423–1429

    PubMed  CAS  Google Scholar 

  • O’Young J, MxPeek B (1987) Quality of life variables in surgical trials. J Chronic Dis 40:513

    Article  PubMed  Google Scholar 

  • Padilla GV, Presant C, Grant NM, Metter G, Lipsett J, Heide F (1983) Quality of life index for patients with cancer. Res Nurs Health 6:117–126

    Article  PubMed  CAS  Google Scholar 

  • Patrick DL, Erickson P (1988) Assessing health-related quality of life for clinical decision making. In: Walker SR, Rosser RM (eds) Quality of life: assessment and application. MTP Press, Lancaster, pp 9–50

    Google Scholar 

  • Priestman TJ, Baum M (1976) Evaluation of quality of live in patients receibing treatment for advanced breast cancer. Lancet 1:899–901

    Article  PubMed  CAS  Google Scholar 

  • Read JL (1988) The new area of quality of life assessment. In: Walker SR, Rosser RM (eds) Quality of life: assessment and application. MTP Press, Lancaster, pp 1–8

    Google Scholar 

  • Rohde H, Rau E, Gebbensleben B (1984) Ergebnisse der Bestimmung des Lebensqualitätsindex nach Spitzer in der multizentrischen Magenkarzinom TNM-Studie. In: Rohde H, Troidl H (Hrsg) Das Magenkarzinom. Thieme, Stuttgart, S 63–74

    Google Scholar 

  • Rosser R (1988) Quality of life: consensus, controversy and concern. In: Walker SR, Rosser RM (eds) Quality of life: assessment and application. MTP Press, Lancaster, pp 297–305

    Google Scholar 

  • Schag CC, Heinrich RL, Ganz PA (1984) Cancer inventory of problem solving functions (CIPS) an instrument for assessing cancer patients rehabilitation needs. J Psychosoc Oncol 11–24

    Google Scholar 

  • Schipper H, Clinch J (1988) Assessment of treatment in cancer. In: Teeling-Smith G (ed) Measuring health: a practical approach. Wiley, Chicester, pp 109–156

    Google Scholar 

  • Schipper H, Clinch J, McMurray A, Levitt M (1984) Measuring the quality of life of cancer patients: The functional living index cancer: Development and validation. J Clin Oncol 2 2:472–483

    PubMed  CAS  Google Scholar 

  • Schuster S, Heim ME, Andres R, Queißer W (1986) Lebensqualität von Karzinom-Patienten unter Chemo- und Radiotherapie. Onkologie 9:172–180

    Article  PubMed  CAS  Google Scholar 

  • Selby PJ (1988) Measuring the quality of life of patients with cancer. In: Walker SR, Rosser RM (eds) Quality of life: assessment and application. MTP Press, Lancaster, pp 181–204

    Google Scholar 

  • Selby PJ, Chapman JA, Etazadi-Amoli J, Dalley D, Boyd NF (1984) The development of a method for assessing the quality of life of cancer patients. Br J Cancer 50 1:13–22

    Article  PubMed  CAS  Google Scholar 

  • Spitzer WO (1987) State of science 1986: Quality of life functional status as target variables for research. J Chronic Dis 40 6:465–471

    Article  PubMed  CAS  Google Scholar 

  • Spitzer WO, Dobson AJ, Hall J et al. (1981) Measuring the quality of life of cancer patients. A concise QL-index for use by physicians. J Chronic Dis 34:585–597

    Article  PubMed  CAS  Google Scholar 

  • Tannock IF (1987) Treating the patient, not just the cancer. N Engl J Med 317:1534–1535

    Article  PubMed  CAS  Google Scholar 

  • Teeling-Smith G (1988) Measuring health — a practical approach. Wiley, Chicester

    Google Scholar 

  • Troidl H, Kusche J, Vestweber KH, Eypasch E, Koeppen L, Bouillon B (1987) Quality of life: An important endpoint both in surgical practice and research. J Chronic Dis 40:523–528

    Article  PubMed  CAS  Google Scholar 

  • Ventafridda V, Dam FSAM van, Yancik R, Tamburini M (eds) (1986) Assessment of quality of life and cancer treatment. Elsevier, Amsterdam

    Google Scholar 

  • Walker SR, Rosser RM (1988) Quality of life assessment and application. MTP Press, Lancaster

    Google Scholar 

  • Ware JE (1984a) Methodology in behavioral and psychosocial cancer research. Conceptualizing disease impact and treatment outcomes. Cancer [Suppl 10] 53:2316–2326

    Google Scholar 

  • Ware JE (1984b) Methodological considerations in health status assessment procedures. In: Wenger NK, Mattson ME, Furberg CD, Elinson J (eds) Assessment of quality of life in clinical trials of cardiovascular therapies. LeJacq, New York, pp 87–117

    Google Scholar 

  • Ware JE (1987) Standards for validating health measures: Definition and content. J Chronic Dis 40:503–512

    Article  Google Scholar 

  • Wenger NK (1986) Quality of life: concept and approach to measurement. Adv Cardiol 33:122–130

    PubMed  CAS  Google Scholar 

  • Wenger NK, Mattson ME, Furberg CD, Elinson J (1984) Assessment of quality of life in clinical trials of cardiovascular therapies. Am J Cardiol 54:908–913

    Article  PubMed  CAS  Google Scholar 

  • Wood-Dauphinee S, Troidl H (1986) Endpoints for clinical studies: Conventional and innovative variables. In: Troidl H, Spitzer WO, McPeek B, Mulder DS, McKneally MF (eds) Principles and practice of research strategies for surgical investigators. Springer, New York, pp 53–68

    Google Scholar 

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Authors
  1. M. Bullinger
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Editors and Affiliations

  1. Abteilung für Medizinische Psychologie, Universitätskrankenhaus Hamburg-Eppendorf, Martinistr. 52, D-2000, Hamburg 20, Deutschland

    Rolf Verres

  2. Abteilung für Medizinische Psychologie, Universitätsnervenklinik Kiel, Niemannsweg 147, D-2300, Kiel 1, Deutschland

    Monika Hasenbring

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© 1989 Springer-Verlag Berlin Heidelberg

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Bullinger, M. (1989). Forschungsinstrumente zur Erfassung der Lebensqualität bei Krebs — ein Überblick. In: Verres, R., Hasenbring, M. (eds) Psychosoziale Onkologie. Jahrbuch der medizinischen Psychologie, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74986-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-74986-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51519-7

  • Online ISBN: 978-3-642-74986-5

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