Abstract
Our comprehension of the significance of specific and nonrandom chromosome changes in leukemia and other malignant diseases has increased enormously during the last decade. The rise of tumor cytogenetics was caused by the development of refined chromosome banding techniques which allowed the detection of chromosomal rearrangements that had previously been overlooked. With the improvement of these techniques, chromosome anomalies can now be demonstrated in many more patients with malignant tumors and premalignant diseases than had been imagined only a few years ago.
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Fonatsch, C., Gradl, G. (1988). Cytogenetic Findings in Myeloproliferative Disorders. In: Huhn, D., Hellriegel, K.P., Niederle, N. (eds) Chronic Myelocytic Leukemia and Interferon. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73526-4_1
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DOI: https://doi.org/10.1007/978-3-642-73526-4_1
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