Abstract
The last 10 years have seen something of a revolution in experimental carcinogenesis, sparked by the discovery of oncogenes [1–3]. The first such gene and most of the ones that followed [1] have been isolated as part of the genome of a tumor-inducing retrovirus. Mostly obtained from birds and mice, these viral oncogenes are nearly identical to genes present in normal cells and, because of their high degree of evolutionary conservation, could be used directly to isolate their human counterparts.
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Rapp, U.R., Storm, S.M., Cleveland, J.L. (1987). Oncogenes: Clinical Relevance. In: Neth, R., Gallo, R.C., Greaves, M.F., Kabisch, H. (eds) Modern Trends in Human Leukemia VII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 31. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72624-8_97
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DOI: https://doi.org/10.1007/978-3-642-72624-8_97
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