Summary
A porous steroid-eluting electrode gives stable, low chronic thresholds without peaking in animal studies. Controlled steroid release at the tissue-electrode interface affects only a few myocardial cells, precluding systemic side effects. Human studies so far confirm the animal results. This will allow the use of much lower pulse generator voltage and pulse width without compromising safety. When combined with appropriate pacing circuits, the new electrode’s low polarization characteristics may allow reliable capture detection.
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References
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© 1983 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt
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Stokes, K.B., Bornzin, G.A., Wiebusch, W.A. (1983). A Steroid-Eluting, Low-Threshold, Low-Polarizing Electrode. In: Steinbach, K. (eds) Cardiac Pacing. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-72367-4_55
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DOI: https://doi.org/10.1007/978-3-642-72367-4_55
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-642-72369-8
Online ISBN: 978-3-642-72367-4
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