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Lectins and Blood Group Substances as “Tumor Markers”

  • Chapter
Morphological Tumor Markers

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 77))

Abstract

In recent decades, research efforts have been focused on demonstrating changes in cell surface membrane during neoplastic transformation. This emphasis stems from the observation that the cell surface membrane may determine several characteristics of neoplastic cells such as decreased adhesion, loss of contact inhibition, increased growth rate, prolonged survival, increased invasiveness and motility, expression of “new” antigens and escape from immunological surveillance (review for glycolipids and glycoproteins in cancer: EMMELOT 1973; KÖTTGEN et al. 1979; YOGEESWARAN 1983; HAKOMORI 1984; BAENZINGER 1986).

Supported by the Sonderforschungsbereich 232 and by the Hamburger Stiftung zur Förderung der Krebsbekämpfung

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  1. Institut für Pathologie, Universität Hamburg, Martinistraße 52, D-2000, UKE, Hamburg 20, Germany

    Gerhard Seifer

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Caselitz, J. (1987). Lectins and Blood Group Substances as “Tumor Markers”. In: Seifer, G. (eds) Morphological Tumor Markers. Current Topics in Pathology, vol 77. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71356-9_11

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