Skip to main content
SpringerLink
Log in

Genital and Anal Papillomavirus Infections in Human Males

  • Chapter
Papillomaviruses and Human Disease

Abstract

Genital warts were familiar to physicians in ancient times, who called them ‘condylomas’ or ‘figs’ (Bafverstedt 1967). In the eighteenth and nineteenth centuries the disease was common, and was wrongly attributed first to syphilis, then to gonorrhoea, then to irritation from secretions “disturbed by venery” — hence the synonym ‘venereal’ warts. Knowledge about the true etiology of genital warts came slowly. Their histological similarity to cutaneous warts was noted in the 1890s, and subsequently some experimental inoculations of extracts of penile warts into nongenital epithelia resulted in the development of skin warts (Oriel 1971 a). The viral etiology of cutaneous warts was confirmed by electron microscopy in the late 1940s, and it was assumed that genital warts were caused by the same virus. Not until the advent of molecular virology was this opinion shown to be incorrect.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ananthakrishnan N, Ravindran R, Veliath AJ, Parkash S (1981) Loewenstein-Buschke tumour of penis - a carcinomimic. Report of 24 cases and review of literature. Br J Urol 53: 460–465

    Article  PubMed  CAS  Google Scholar 

  • Bafverstedt B (1967) Condylomata acuminata - past and present. Acta Derm Venereol (Stockh) 47: 376–381

    CAS  Google Scholar 

  • Barrett TJ, Silbar JD, McGinley JP (1954) Genital warts - a venereal disease. JAMA 154: 333–334

    CAS  Google Scholar 

  • Baruah MC, Sardari L, Selvaraju M, Veliath AJ (1984) Perianal condylomata acuminata in a male child. Br J Vener Dis 60: 60–61

    PubMed  CAS  Google Scholar 

  • Bender ME, Pass F (1981) Papillomavirus and cutaneous malignancy. Int J Dermatol 20: 468–474

    Article  PubMed  CAS  Google Scholar 

  • Bissada NK, Cole AT, Fried FA (1974) Extensive condylomata acuminata of the entire male urethra and the bladder. J Urol 112: 201–203

    PubMed  CAS  Google Scholar 

  • Campion MJ, Singer A, Clarkson PK, McCance DJ (1985) Increased risk of cervical neoplasia in the consorts of men with penile condylomata acuminata. Lancet i: 943–945

    Article  Google Scholar 

  • Carr G, William DC (1977) Anal warts in a population of gay men in New York City. Sex Transm Dis 4: 56–57

    Article  PubMed  CAS  Google Scholar 

  • Cetti NE (1984) Condyloma acuminatum of the urethra: problems in eradication. Br J Surg 71: 57

    Article  PubMed  CAS  Google Scholar 

  • Chamberlain MJ, Reynolds AL, Yeoman WB (1972) Toxic effect of podophyllum in pregnancy. Br Med J 3: 391–392

    Article  PubMed  CAS  Google Scholar 

  • Chapel TA, Rahbari H (1980) Genital bowenoid papulosis - squamous-cell carcinoma in situ. Sex Transm Dis 7: 139–141

    Article  PubMed  CAS  Google Scholar 

  • Chief Medical Officer (1974) Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security for the year 1972. Br J Vener Dis 50: 73–79

    Google Scholar 

  • Chief Medical Officer (1985) Sexually transmitted diseases. Extract from the annual report of the Chief Medical Officer to the Department of Health and Social Security for the year 1982. Br J Vener Dis 60: 199–203

    Google Scholar 

  • Chuang T-Y, Perry HO, Kurland LT, Ilstrup DM (1984) Condylomata acuminata in Rochester Minnesota 1950–1978: 1. Epidemiology and clinical features. Arch Dermatol 120: 469–475

    Article  PubMed  CAS  Google Scholar 

  • Davies SW (1965) Giant condyloma acuminatum: incidence among cases diagnosed as carcinoma of the penis. J Clin Pathol 18: 142–149

    Article  PubMed  CAS  Google Scholar 

  • Dawson DF, Duckworth JK, Bernhardt H, Young JM (1965) Giant condyloma and verrucous carcinoma of the genital area. Arch Pathol 79: 225–231

    PubMed  CAS  Google Scholar 

  • de Benedictis TJ, Marmar JL, Praiss DE (1977) Intraurethral condylomata acuminata: management and a review of the literature. J Urol 118: 767–769

    Google Scholar 

  • de Jong AR, Weiss JC, Brent RL (1982) Condylomata acuminata in children. Am J Dis Child 136: 704–706

    PubMed  Google Scholar 

  • Dean P, Lancaster WD, Chun B, Jenson AB (1983) Human papillomavirus structural antigens in squamous papilloma of the male urethra. J Urol 129: 873–875

    PubMed  CAS  Google Scholar 

  • Dexter HLT, Rockwell EM (1951) Simultaneous condylomata acuminata and condylomata lata. Report of a case. Arch Dermatol Syph 64: 205–207

    CAS  Google Scholar 

  • Dretler SP, Klein LA (1975) The eradication of intraurethral condylomata acuminata with 5 percent 5-fluorouracil cream. J Urol 113: 195–198

    PubMed  CAS  Google Scholar 

  • Dunn AEG, Ogilvie MM (1968) Intranuclear virus particles in human genital wart tissue: observations on the ultrastructure of the epidermal layer. J Ultrastruct Res 22: 282–295

    Article  Google Scholar 

  • Editorial note (1983) Condyloma acuminatum — United States 1966–1981. JAMA 250: 336

    Google Scholar 

  • Ejeckam GC, Idikio HA, Nayak V, Gardiner JP (1983) Malignant transformation in an anal condyloma acuminatum. Can J Surg 26: 170–173

    PubMed  CAS  Google Scholar 

  • Farris GM, Statham BN, Waugh MA (1984) The investigation of patients with genital warts. Br J Dermatol 111: 736–738

    Article  Google Scholar 

  • Fitzgerald DM, Hamit HF (1974) The variable significance of condylomata acuminata. Ann Surg 179: 328–331

    Article  PubMed  CAS  Google Scholar 

  • Gissmann L, de Villiers EM, zur Hausen H (1982) Analysis of human genital warts (condylomata acuminata) and other genital tumours for human papillomavirus type 6 DNA. Int J Cancer 29: 143–146

    Article  PubMed  CAS  Google Scholar 

  • Gross G, Hagedorn M, Ikenberg H, Rufli T, Dahlex C, Grosshans E, Gissmann L (1985) Bowenoid papulosis. Presence of human papillomavirus (HPV) structural antigens and of HPV 16-related sequences. Arch Dermatol 121: 858–863

    Article  PubMed  CAS  Google Scholar 

  • Hajek EF (1956) Contribution to the etiology of laryngeal papilloma in children. J Laryngol Otol 70: 166–168

    Article  PubMed  CAS  Google Scholar 

  • Harahap M (1979) Asymptomatic gonorrhoea among patients with condylomata acuminata. Br J Vener Dis 55: 450

    PubMed  CAS  Google Scholar 

  • Ikenberg H, Gissmann L, Gross G, Grußendorf-Conen E, zur Hausen H (1983) Human papillomavirus type 16-related DNA in genital Bowen’s disease and in bowenoid papulosis. Int J Cancer 32: 563–565

    Article  PubMed  CAS  Google Scholar 

  • Kinghorn GR (1978) Genital warts: incidence of associated genital infections. Br J Dermatol 99: 405–409

    Article  PubMed  CAS  Google Scholar 

  • Lever WF (1967) Histopathology of the skin, 4th edn. Pitman Medical, London, pp 375–382

    Google Scholar 

  • Levine RU, Crum CP, Herman E, Silvers D, Ferenczy A, Richart RM (1984) Cervical papillomavirus infection and intraepithelial neoplasia: a study of male sexual partners. Obstet Gynecol 64: 16–20

    PubMed  CAS  Google Scholar 

  • Lock MR, Katz DR, Sammoorian S, Parks AC (1977) Giant condyloma of the rectum: report of a case. Dis Colon Rectum 20: 154–157

    Article  PubMed  CAS  Google Scholar 

  • Lupulescu A, Mehregan DH, Rahbavi H (1977) Bowen’s disease of genital areas. J Cutan Pathol 4: 266–274

    Article  PubMed  CAS  Google Scholar 

  • Masse S, Tosi-Kruse A, Carmel M, Elhilali M (1981) Condyloma acuminatum of bladder. Urology 17: 381–382

    Article  PubMed  CAS  Google Scholar 

  • McCance D (1986) Human papillomaviruses infecting the genital tract. In: Oriel JD, Harris JRW (eds) Recent advances in sexually transmitted diseases. Churchill Livingstone, Edinburgh

    Google Scholar 

  • Medley G (1984) Anal smear test to diagnose occult anorectal infection with human papillomavirus in men. Br J Vener Dis 60: 205

    PubMed  CAS  Google Scholar 

  • Morrow RP, McDonald JR, Emmett JL (1952) Condylomata acuminata of the urethra. J Urol 68: 909–917

    PubMed  Google Scholar 

  • Nielsen HV (1975) Condylomata acuminata of the bladder (case report). Scand J Urol Nephrol 9: 169–170

    Article  PubMed  CAS  Google Scholar 

  • Oriel JD (1971a) Natural history of genital warts. Br J Vener Dis 47: 1–13

    PubMed  CAS  Google Scholar 

  • Oriel JD (1971b) Anal warts and anal coitus. Br J Vener Dis 47: 373–376

    PubMed  CAS  Google Scholar 

  • Oriel JD, Almeida JD (1970) Demonstration of virus particles in human genital warts. Br J Vener Dis 46: 37–42

    PubMed  CAS  Google Scholar 

  • Oriel JD, Whimster I (1971) Carcinoma in situ associated with virus-containing anal warts. Br J Dermatol 84: 71–73

    Article  PubMed  CAS  Google Scholar 

  • Pollack HM, de Benedictis TJ, Marmar JL, Praiss DE (1978) Urethrographic manifestations of venereal warts (condylomata acuminata). Radiology 126: 643–646

    PubMed  CAS  Google Scholar 

  • Rhatigan RM, Jimenez S, Chopskie EJ (1972) Condyloma acuminatum and carcinoma of the penis. South Med J 65: 423–428

    Article  PubMed  CAS  Google Scholar 

  • Ridley CM (1983) Vulval dysplasia. J Hosp Med 30: 223

    Google Scholar 

  • Schlappner OLA, Shaffer EA (1978) Anorectal condylomata acuminata: a missed part of the condyloma spectrum. Can Med Assoc J 118: 172–173

    PubMed  CAS  Google Scholar 

  • Shah IC, Hertz RE (1972) Giant condyloma acuminatum of the anorectum. Dis Colon Rectum 15: 207–210

    Article  PubMed  CAS  Google Scholar 

  • Singer A, McCance D (1985) The wart virus and genital neoplasia; a casual or causal association. Br J Obstet Gynaecol 92: 1083–1085

    Article  PubMed  CAS  Google Scholar 

  • South LM, O’Sullivan JP, Gazet JC (1977) Giant condyloma of Buschke and Loewenstein. Clin Oncol 3: 107–115

    PubMed  CAS  Google Scholar 

  • Stein DS (1980) Transmissible venereal neoplasia: a case report. Am J Obstet Gynecol 137: 864–865

    PubMed  CAS  Google Scholar 

  • Sturm JT, Christenson CE, Uecker JH, Perry JF (1975) Squamous-cell carcinoma of the anus arising in a giant condyloma acuminatum: report of a case. Dis Colon Rectum 18: 147–151

    Article  PubMed  CAS  Google Scholar 

  • Tessler AN, Applebaum SM (1982) The Buschke-Loewenstein tumour. Urology 20: 36–39

    Article  PubMed  CAS  Google Scholar 

  • Thomson JFS, Grace RH (1978) Treatment of perianal and anal condylomata acuminata. A new operative technique. J R Soc Med 71: 181–185

    Google Scholar 

  • Wade TR, Koppf AW, Ackerman AB (1979) Bowenoid papulosis of the genitalia. Arch Dermatol 115: 306–308

    Article  PubMed  CAS  Google Scholar 

  • zur Hausen H, Gissmann L, Schlehofer JR (1984) Viruses in the aetiology of human genital cancer. Prog Med Virol 30: 170–186s

    PubMed  Google Scholar 

Download references

Authors
  1. J. D. Oriel
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Laboratory of Pathology & Cancer Research, Finnish Cancer Society, Kiekkotie 2, SF-70200, Kuopio, Finland

    Kari J. Syrjänen M.D. (Director) (Director)

  2. Institut für Virusforschung, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-6900, Heidelberg, West Germany

    Lutz Gissmann (Prof. Dr. rer. nat.) (Prof. Dr. rer. nat.)

  3. Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, 10467, Bronx, New York, USA

    Leopold G. Koss M.D. (Professor and Chairman) (Professor and Chairman)

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Oriel, J.D. (1987). Genital and Anal Papillomavirus Infections in Human Males. In: Syrjänen, K.J., Gissmann, L., Koss, L.G. (eds) Papillomaviruses and Human Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71097-1_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-71097-1_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71099-5

  • Online ISBN: 978-3-642-71097-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation