Abstract
Management and prevention of rejection by effective immunosupressive therapy are two of the most important problems of small-bowel transplantation. Cyclosporine A, already used in clinical organ grafting with great success, has greatly prolonged the survival times of experimentally transplanted small intestines (Diliz-Perez et al. 1984; Raju et al. 1984). Although the exact identity of the cells causing morphological graft destruction is not yet know, T cells are thought to play a significant role in this process (Loveland and Mckenzie 1982; Lowry et al. 1982; Asher et al. 1983; Gurley et al. 1983). With the availability of monoclonal antibodies, an identification of T cell subsets with different functions is now possible.
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References
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© 1986 Springer-Verlag Berlin Heidelberg
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Liedgens, P., Müller-Hermelink, H.K., Deltz, E. (1986). Rejection in Heterotopic Small-Bowel Transplantation. In: Deltz, E., Thiede, A., Hamelmann, H. (eds) Small-Bowel Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71087-2_25
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DOI: https://doi.org/10.1007/978-3-642-71087-2_25
Publisher Name: Springer, Berlin, Heidelberg
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