Abstract
In the mammalian brain information transfer occurs through the release of chemical messengers or transmitter substances at synapses. For several years it was believed that each neurone contained and released only one chemical transmitter (the so-called Dale’s Principle) but it is now known that each branch of a neurone may release several different substances which can influence synaptic transmission. As recently as 1970, only ten substances, acetylcholine, some amino acids and monoamines were thought to be involved in chemical transmission. In 1987 this number exceeds 50, with the discovery in nerve cells of a number of peptides with potential chemical messenger function.
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McQueen, J.K. (1987). Classical Transmitters and Neuromodulators. In: Transmitter Molecules in the Brain. Basic and Clinical Aspects of Neuroscience, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69950-4_2
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DOI: https://doi.org/10.1007/978-3-642-69950-4_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-13701-6
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