Abstract
The HLA-D-segregant series of lymphocyte activating determinants (Lads) was originally described by using homozygous cells as reagents in mixed lymphocyte cultures (MLC). Later, the serological definition of the HLA-DR antigens was established by using HLA-D homozygous cells (HTCs) as reference cells. It appeared in Caucasoid panels that the two techniques were detecting the same antigenic determinants. Further serological, biochemical, and DNA studies have now revealed the complexity of the HLA-D region, but the relationship between D and DR remains unresolved.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Jaraquemada, D., Okoye, R., Ollier, W., Awad, J., Festenstein, H. (1984). HLA-D and DR in Different Populations. In: Albert, E.D., et al. Histocompatibility Testing 1984. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69770-8_163
Download citation
DOI: https://doi.org/10.1007/978-3-642-69770-8_163
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69772-2
Online ISBN: 978-3-642-69770-8
eBook Packages: Springer Book Archive