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Electrophysiological Effects of Antiepileptic Drugs

  • Chapter
Antiepileptic Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 74))

Abstract

This chapter will attempt to correlate the anticonvulsant action of antiepileptic agents with the effects of these drugs on electrophysiological parameters. Effects of antiepileptic or anticonvulsant drugs have been determined in neurons showing both normal behavior and abnormal activity due to direct or transsynaptic activation at high frequencies, treatment with different convulsant agents, or localization within or in the vicinity of an epileptogenic focus produced by local lesioning or application of cobalt or penicillin.

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Authors
  1. I. Jurna
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  1. Laboratorium für Pharmakologie und Toxikologie Fachbereich Veterinärmedizin, Freie Universität Berlin, Koserstraße 20, D-1000, Berlin 33, Germany

    Hans-Hasso Frey

  2. Abteilung für Neurologie, Klinikum Charlottenburg, Spandauer Damm 130, D-1000, Berlin 19, Germany

    Dieter Janz

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Jurna, I. (1985). Electrophysiological Effects of Antiepileptic Drugs. In: Frey, HH., Janz, D. (eds) Antiepileptic Drugs. Handbook of Experimental Pharmacology, vol 74. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69518-6_23

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  • DOI: https://doi.org/10.1007/978-3-642-69518-6_23

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