Abstract
A large part, perhaps even the majority, of inflammatory diseases of the respiratory tract are caused by viral infection. The pathoanatomical changes associated with banal viral infections (common cold) of the upper respiratory tract, may be readily observed in biopsies from the nasal mucosa as documented in studies by Hilding (1930) and Tyrell and Parsons (1960).
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References
Adams JM (1941) Primary virus pneumonitis with cytoplasmic inclusion bodies. Jama 116:925–933
Adams JM, Imagawa DT, Zike K (1961) Epidemic bronchiolitis and pneumonitis related to respiratory syncytial virus. Jama 176:1037–1039
Aherne W, Bird T, Court SDM, Gardner PS, McQuillen J (1970) Pathological changes in virus infections of the lower respiratory tract in children. J Clin Pathol 23:7–18
Alagna G (1911) Histopathologische Veränderungen der Tonsillen und der Schleimhaut der ersten Luftwege bei Masern. Arch Laryng Rhin 25:527–530
Almeida JD (1963) A classification of virus particles based on morphology. Can Med Assoc J 89:787–798
Archibald RWR, Weller RO, Meadow SR (1971) Measles pneumonia and the nature of the inclusion-bearing giant cells: A light- and electronmicroscope study. J Pathol 103:27–34
Arrobbio J (1964) Infection with parainfluenza 3 virus: a fatal case with autopsy report. Clin Proc Child Hosp Nat Med Cent 20:298–305
Beale AJ, Doane F, Ormsby HL (1957) Studies on adenovirus infections of the eye in Toronto. Am J Opthalmol 43:26–31
Becroft DMO (1967) Histopathology of fatal adenovirus infection of the respiratory tract in young children. J Clin Pathol 20:561–569
Beem M, Wrigth FH, Hamre D, Egerer R, Oehme M (1960) Association of the chimpanzee coryza agent with acute respiratory disease in children. N Engl J Med 263: 523–530
Bell JA, Dingle JH, Francis T, Hilieman MR, Huebner RJ, Payne AM-M (1956)
“Adenoviruses”: Group name proposed for new respiratory tract viruses. Science 124:119–120
Bellanti JA (1971) Biologic significance of the secretory yA immunoglobulins. Pediatrics 48:715–729
Blandford G (1970) Arthus reaction and pneumonia. Br Med J I:758–760
Blank H, Davis C, Collins C (1970) Electron microscopy for diagnosis of cutaneous viral infections. Br J Dermatol 83:69–80
Brody AR, Craighead JE (1974) Pathogenesis of pulmonary cytomegalovirus infection in immunosuppressed mice. J Infect Dis 129:677–689
Buescher EL (1967) Respiratory disease and the adenoviruses. Med Clin North Am 51:769–779
Burnett FM (1968) Measles as an index of immunological function. Lancet II:610–613
Buser F (1967) Side reaction to measles vaccination suggesting the Arthus phenomenon. N Engl J Med 277:250–251
Buthala BA, Soret MG (1964) Parainfluenzy type 3 virus infection in hamsters: virologic, serologic and pathologic studies. J Infect Dis 114:226–234
Carilli AD, Gohd RS, Gordon W (1964) A virologic study of chronic bronchitis. N Engl J Med 270:123–127
Cascardo H, Karzon DT (1965) Measles virus giant cell inducing factor (fusing factor). Virology 26:311–325
Chanock RM, Parrott RH (1965) Respiratory syncytial virus. In: Horsfall FL Jr, Tamm I (eds) Viral and rickettsial diseases of man. Lippincott, Philadelphia, pp 775–783
Chanock RM, Parrott RH, Kapikian AZ, Kein HW, Brandt CD (1968) Possible role of immunological factors in pathogenesis of RS virus lower respiratory tract disease. In: Pollard M (ed) Perspectives in virology, vol VI. Academic Press, New York, pp 125–139
Chanock RM, Kapikian AZ, Mills J, Kein HW, Parrott RH (1970) Influence of immunological factors in respiratory syncytial virus disease of the lower respiratory tract. Arch Environ Health 21:347–355
Chany C, Lépine P, Lelong M, Le-Tan Vinh, Satge O, Virat J (1958) Severe and fatal pneumonia in infants and young children associated with adenovirus infections. Am J Hyg 67:367–378
Choppin PW, Scheid A (1980) The role of viral glykoproteins in adsorption, penetration and pathogenicity of viruses. Rev Infect Dis 2:40–60
Chown B (1939) Giant cell pneumonia of infancy as a manifestation of vitamin A deficiency. Am J Dis Child 57:489–505
Coates HV, Chanock RM (1962) Experimental infection with respiratory syncytial virus in several species of animals. Am J Hyg 76:302–312
Cohen SM, Gordon J, Rapp F, Macauley JC, Bickley SM (1955) Cited by Spencer. Proc Soc Exp Biol Med 90:118
Cole R, Kuttner AG (1926) A filtrable virus present in the submaxillary glands of guinea pigs. J Exp Med 44:855–873
Cowdry EV (1934) The problems of intranuclear inclusions in virus diseases. Arch Pathol 18:527–542
Craighead JE (1971) Pulmonary cytomegalovirus infection in the adult. Am J Pathol 63:487–504
Dahm HH (1980) Zytomegalie des Neugeborenen und des Erwachsenen. Med Welt 31:64–69
Davis BJ, Ornstein L (1959) High resolution enzyme localization with a new diazo reagent, “hexazonium pararosaniline”. J Histochem Cytochem 7:297
Deinhardt F, May RD, Calhoun HH, Sullivan HE (1958) The isolation of adenovirus type 1 from a fatal case of viral “pneumonitis”. Arch Intern Med 102:816
Delage B, Bronchu P, Pelletier M, Jasmin G, Lapointe N (1979) Giant cell pneumonia caused by parainfluenza virus. J Pediatr 94:426–429
De Monbreun WA (1937) The histopathology of natural and experimental canine distemper. Am J Pathol 13:187–212
Denton J (1925) The pathology of fatal measles. Am J Med Sci 169:531–543
Dingle JH, Feller AE (1956) Noninfluenzal viral infections of the respiratory tract. N Engl J Med 254:465–471
Doane FW, Anderson N, Zbitnew A, Rhodes AJ (1969) Application of electron microscopy to the diagnosis of virus infections. Can Med Assoc J 100:1043–1049
Dürck H (1897) Studien über die Aetiologie und Histologie der Pneumonie im Kindesalter und die Pneumonien im Allgemeinen. Dtsch Arch Klin Med 58:368–444
Effros RB, Doherty PC, Gerhard W, Bennink J (1977) Cited by Lin Yun Lu et al. (1981). J Exp Med 145:557–568
Enders JF (1956) The present status of etiologic discovery in viral diseases. Ann Intern Med 45:331–350
Enders JF, McCarthy FK, Mitus A, Cheatham WJ (1959) Isolation of measles virus at autopsy in cases of giant-cell pneumonia without rash. N Engl J Med 261:875–881
Evans AS (1958) Latent adenovirus infections of the human respiratory tract. Am J Hyg 67:256–266
Farber S, Wolbach SB (1932) Intranuclear and cytoplasmic inclusions (“protozoan-like bodies) in the salivary glands and other organs of infants. Am J Pathol 8:123–135
Farr GH, Russell AH, Hennigar GR (1970) Desquamative interstitial pneumonia. Am J Pathol 60:347–370
Feyrter F (1925) Ueber die Masernpneumonia. Virchows Arch 255:753–794
Finkeldey W (1931) Über die Riesenzellbefunde in den Gaumenmandeln, zugleich ein Beitrag zur Histopathologic der Mandelveränderungen im Maserninkubationsstadium. Virchows Arch [Pathol Anat] 281:311–329
Finkeldey W (1932) Riesenzellbefunde bei akuter Wurmfortsatzentzündung. Ein Beitrag zur Histopathologic der Veränderungen des Wurmfortsatzes im Maserninkubationsstadium. Virchows Arch [Pathol Anat] 284:528
Fohlmeister I, Schaefer HE, Rieger M, Galanski M (1979) Masernriesenzellpneumonie. Med Welt 30:307–312
Francis T, Stuart-Harris CH (1938) Studies on nasal histology of epidemic influenza virus infection in ferret. J Exp Med 68:789–802
Frank L (1950) Varicella pneumonitis. Report of a case with autopsy observations. Arch Pathol Lab Med 50:450–456
Friedländer (1876) Experimentaluntersuchungen über chronische Pneumonie und Lungenschwindsucht. Virchows Arch [Pathol Anat] 68:325–363
Friedman HM (1981) Cytomegalovirus: subclinical infection or disease? Am J Med 70:215–217
Gardner PS, Turk DC, Aherne WA, Bird T, Holdaway MD, Court SDM (1967) Deaths associated with respiratory tract infection in childhood. Br Med J IV:316–320
Geiler G (1957) Über die Erwachsenenform der Cytomegalie. Frankf Z Pathol 68:107–118
Gerbeaux MJ, Héber-Jouas J, Masse N, Beauchchef A (1957) Epidémie familiale de maladie à virus du groupe A.P.C. chez trois enfants (un cas mortel). Bull Soc Méd Hôp Paris 73:519
Giese W (1960) Die Atemorgane. In: Kaufmann E, Staemmler M (eds) Lehrbuch der speziellen pathologischen Anatomie, vol II/3. de Gruyter, Berlin
Glahn WC von, Pappenheimer AM (1925) Intranuclear inclusions in visceral disease. Am J Pathol 1:445–466
Glezen WP, Loda FA, Clyde WA, Senior RJ, Shaeffer CI, Conley WG, Denny FW (1971) Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice. J Pediatr 78:397–406
Goodpasture EW (1919) The significance of vertain pulmonary lesions in relation to the etiology of influenza. Am J Med Sci 158:863–870
Goodpasture EW, Talbot FB (1921) Conerning the nature of “protozoan-like” cells in certain lesions on infancy. Am J Dis Child 21:415–425
Goodpasture EW, Auerbach SH, Swanson HS, Cottir EF (1939) Virus pneumonia of infants secondary to epidemic infections. Am J Dis Child 57:937–1011
Green RG, Evans CA (1939) Comparative study of distemper inclusions. Am J Hyg (Sect B) 29:73–87
Gross PA, Green RH, McCrea-Curnen MG (1973) Persistent infection with parainfluenza type 3 virus in man. Am Rev Respir Dis 108:894–898
Günther M, Schaefer HE (1981) Nachweis von Viren in Speicheldrüsen europäischer und algerischer Igel — ein neuer Aspekt der Selbstbespeichelung. Dtsch Ges Säugetierkunde, Heidelberg
Güthert H, Meerbach W, Wöckel W (1969) Vorkommen und Bedeutung der Riesenzellen in der Lunge. 2. Mitteilung: Die mehrkernigen Riesenzeilen. Zentralbl Allg Pathol 112:22–30
Hall CB (1931) Nosocomial viral respiratory infections: Perennial weeds on pediatric wards. Am J Med 70:670–676
Hall CB, Kopeiman AE, Douglas RG, Geiman JM, Meagher MP (1979) Neonatal respiratory syncytial virus infection. N Engl J Med 300:393–396
Hamperl H (1956) Pneumocystis infection and cytomegaly of the lungs in the new-born and adult. Am J Pathol 32:1–13
Hathaway BM (1935) Generalized dissemination of giant cells in lymphoid tissue in prodromal stage of measles. Arch Pathol Lab Med 19:819–824
Hecht V (1910) Die Riesenzellpneumonie im Kindesalter. Eine histologisch-experimentelle Studie. Beitr Pathol Anat Allg Pathol 48:263–310
Hers JFPh (1963) Fluorescent antibody technique in respiratory viral diseases. Am Rev Dis [Suppl] 88:316–338
Hers JFPh, Mulder J (1961) Broad aspects of the pathology and pathogenesis of human influenza. Am Rev Respir Dis 83(2):84–97
Hers JFPh, Masurel N, Mulder J (1958) Bacteriology and histopathology of the respiratory tract and lungs in fatal asian influenza. Lancet II:1141–1143
Hilding A (1930) The common cold. Arch Otolaryngol 12:33–150
Hilleman MR, Werner JH (1954) Recovery of new agent from patients with acute respiratory illness. Proc Soc Exp Biol Med 85:183–188
Himmelweit F (1943) Influenza virus B isolated from fatal case of pneumonia. Lancet II:793–794
Holzel A, Parker L, Patterson WH, White LLR, Thompson KM, Tobin JOH (1963) The isolation of respiratory syncytial virus from children with acute respiratory disease. Lancet I:295–298
Holzel A, Parker L, Patterson WH, Cartmel D, White LLR, Purdy R, Thompson KM, Tobin JOH (1965) Virus isolations from throats of children admitted to hospital with respiratory and other diseases, Manchester 1962–4. Br Med J I:614–619
Hsiung CG (1963) Adenovirus pneumonia in infants and children. Pathologic studies of 40 cases. Chin Med J (Engl) 82:390–398
Ishida N (1957) Cited by Wöckel and Meerbach (1968). Ann NY Acad Sci 67:299
Jarvis WR, Middleton PJ, Gelfand EW (1979) Parainfluenza pneumonia in severe combined immunodeficiency disease. J Pediatr 94:423–524
Jensen KE, Minuse E, Ackermann WW (1955) Serologic evidence of American experience with newborn pneumonitis virus (type Sendai). J Immunol 75:71–77
Jesionek Kiolemenoglou (1904) Ueber einen Befund von protozoenartigen Gebilden in den Organen eines hereditär-luetischen Fötus. Münch Med Wochenschr 51:1905–1907
Joncas J, Berthiaume L, Pavilanis V (1969a) The structure of the respiratory syncytial virus. Virology 38:493–496
Joncas JH, Williams R, Berthiaume L, Beaudry P, Pavilanis V (1969b) Diagnosis of viral respiratory infections by electron microscopy. Lancet I:956–959
Karsner HT, Meyers AE (1913) Giant cell pneumonia. Arch Intern Med 11:534–541
Kawai K (1959) Pathology and pathologic anatomy of adenovirus infection; based on 3 autopsy cases of infantile pneumonia. Jpn J Exp Med 29:359–368
Klein PJ, Bulla M, Newman RA, Müller P, Uhlenbruck G, Schaefer HE, Krüger G, Fischer R (1977) Thomsen-Friedenreich Antigen in haemolytic-uraemic syndrome. Lancet II:1024–1025
Klein PJ, Bulla M, Newman RA, Müller P, Uhlenbruck G, Krüger G, Schaefer HE, Lennartz KJ (1978a) Untersuchungen zur Pathogenese des hämolytisch-urämischen Syndroms. Zentralbl Allg Pathol 122:280
Klein PJ, Newman RA, Uhlenbruck G, Schaefer HE, Lennartz KJ, Fischer R (1978b) Histochemical methods for the demonstration of Thomsen-Friedenreich antigen in cell suspensions and tissue sections. Klin Wochenschr 56:761–765
Klein PJ, Bulla M, Newman RA, Radermacher EH, Müller P, Uhlenbruck G, Krüger G, Schaefer HE, Lennartz KJ, Fischer R (1979) The significance of pneumococcal neuraminidase for the development of haemolytic-uraemic syndrome. In: Bulla M (ed) Dialysis and kidney transplantation in children. Problems and particularities of intermittent longterm dialysis and acute renal failure in children. Bibliomed, Melsungen, pp 183–189
Knyvett AF (1963) The pulmonary lesions of chickenpox. Q J Med 35(N.S.):313–323
Kromayer E (1889) Ueber die sogenannte Katarrhalpneumonie nach Masern und Keuchhusten. Arch Pathol Anat 117:452–468
Kuttner AG, T’Ung T (1935) Further studies on the submaxillary gland viruses of rats and guinea pigs. J Exp Med 62:805–822
Laver WG, Kilbourne ED (1966) Identification in a recombinant influenza virus of structural proteins derived from both parents. Virology 30:493–501
Leder LD (1964) Über die selektive fermentcytochemische Darstellung von neutrophilen myeloischen Zellen und Gewebsmastzellen im Paraffinschnitt. Klin Wochenschr 42:553–555
Lelong M, Lépine P, Alison F, Le-Tan-Vinh, Satgé P, Chany Ch (1956) La pneumonie à virus du groupe A.P.C. chez le nourrisson. Isolement du virus. Les lésions anatomo-histologiques. Arch Fr Pediatr 13:1092–1096
Liebow AA, Steer A, Billingsley JG (1965) Desquamative interstitial pneumonia. Am J Med 39:369–404
Lin Yun Lu, Askonas B (1981) Cross-reactivity for different type A influenza viruses of a cloned T-killer cell line. Nature 288:164–165
Lipschütz Ng (1921) Untersuchungen über die Ätiologie der Krankheiten der Herpesgruppe (Herpes zoster, Herpes genitalis, Herpes febrilis). Arch Dermatol Syph 136:428–482
Llanos-Rodas R, Liu C (1965) A study of measles virus infection in tissue culture cells with particular reference to the development of intranuclear inclusion bodies. J Immunol 95:840–845
Löblich H-J (1981) Personal communication
Löwenstein C (1907) Über protozoenartige Gebilde in den Organen von Kindern. Zentralblatt Allg Pathol Pathol Anat 18:518–518
Louria DB, Blumenfeld HL, Ellis JT, Kilbourne ED, Rogers DE (1959) Studies of influenza in the pandemic of 1957–1958. II. Pulmonary complications of influenza. J Clin Invest 38:213–265
Lucchesi PF, La Boccetta AC, Peale AR (1947) Varicella neonatorum. Am J Dis Child 73:44–54
Luse SA, Smith MG (1965) Electron microscope studies of cells infected with the salivary gland viruses. Ann NY Acad Sci 81:133–144
Martin AM, Kurtz SM (1966) Cytomegalic inclusion disease. An electron microscopic study of the virus at necropsy. Arch Pathol Lab Med 82:27–34
Martin CM, Kunin CM, Gottlieb LS, Fuland M (1959) Asian influenza A in Boston, 1957–1958. II. Severe staphylococcal pneumonia complicating influenza. Arch Intern Med 103:532–542
Masson P, Paré L (1931) Un cas de broncho-pneumonie à plasmodes. Contribution à Fétude du revêtement alvéolaire. Ann Anat Pathol (Paris) 8:13–35
Masugi M, Minami G (1938) Über einen Fall von Masern mit Riesenzellbildung an Luftwegen, Mund- und Rachenschleimhaut. Über die Einschlüsse an Masernriesenzellen. Beitr Pathol Anat Allg Pathol 101:483–502
McAllister RM, Straw RM, Filbert JE, Goodheart CR (1963) Human cytomegalovirus: Cytochemical observations of intracellular lesion development correlated with viral synthesis and release. Virology 19:521–531
McClelland AJ (1980) Vaccination against paramyxoviruses. Nature 284:404
McNair Scott TF, Bonanno DE (1967) Reactions to live-measles virus vaccine in children previously inoculated with killed-virus vaccine. N Engl J Med 277:248–250
McNary WF, Gaensler EA (1971) Intranuclear inclusion bodies in desquamative interstitial pneumonia: Electron microscopic observations. Ann Intern Med 74:404–407
Meerbach W, Wöckel W, Güthert H (1968) Vorkommen und Bedeutung der Riesenzellen in der Lunge. 1. Mitteilung: Die einkernigen Riesenzellen. Zentralbl Allg Pathol Pathol Anat 111:544–550
Merz DC, Scheid A, Choppin PW (1980) Importance of antibodies to the fusion glycoprotein of paramyxoviruses in the prevention of spread of infection. J Exp Med 151:275–288
Mitus A, Enders JF, Craig JM, Holloway A (1959) Persistence of measles virus and depression of antibody formation in patients with giant cell pneumonia. N Engl J Med 261:882–889
Moloney WC, McPherson K, Fliegelman L (1960) Esterase activity in leucocytes demonstrated by the use of naphthol AS-D chloroacetate substrate. J Histochem Cytochem 8:200–207
Moore RA, Gross P (1930) Giant cells in inflammation of the lung in children. Am J Dis Child 40:247–259
Mouchet R (1911) De la présence de protozoaires dans les organes des enfants. Contribution à l’étude de l’ictère des nouveau-nés. Arch Med Exp Anat Pathol (Paris) 23:115–124
Muchmore HG, Parkinson AJ, Humphries JE, Scott LV, Cooney MK, Miles JAR (1981) Persistent parainfluenza virus shedding during isolation at the south pole. Nature 289:187–189
Mufson MA, Krause HE, Mocega HE, Dawson FW (1970) Viruses, mycoplasma pneumoniae and bacteria associated with lower respiratory tract disease among infants. Am J Epidemiol 91:192–202
Mulder J, Verdongk GJ (1949) Studies on the pathogenesis of a case of influenza-A pneumonia of 3 days duration. J Pathol Bacteriol 61:55–61
Myerowitz RL, Stalder H, Oxman MN, Levin MJ, Moore M, Leith JD, Gantz NM, Pellegrini J, Hierholzer JC (1975) Fatal disseminated adenovirus infection in a renal transplant recipient. Am J Med 59:591–598
Nader PR, Horwitz M, Rouseau J (1967) Severe illness (atypical exanthem) following exposure to natural measles: II cases in children previously inoculated with killed vaccine. Presented at a meeting of the American Pediatric Society April, 29
Noda K (1953) Newborn virus pneumonitis, type Sendai. III. Report: Pathological studies on the 9 autopsy cases and the mice inoculated with the new-found virus. Yokohama Med Bull 4:281–287
Norrby E (1966) Present status of killed measles vaccines. Proc Int Conf Vaccines viral ricketsial Dis Man, Washington
Oppenheimer EH (1944) Congenital chickenprox with disseminated visceral lesions. Bull Johns Hopkins Hosp 74:240–250
Osada R, Hanayama R (1958) A fatal case of infantile pneumonia due to adenovirus; clinical findings. Jpn J Exp Med 28:293–295
Parker F, Jolliffe LS, Barnes MW, Finland M (1946) Pathologic findings in the lungs of five cases from which influenza virus was isolated. Am J Pathol 22:797–819
Patchefsky AS (1971) Desquamative interstitial pneumonia: significance of intranuclear viral-like inclusion bodies. Ann Intern Med 74:322–327
Patchefsky AS, Fraimow W, Hoch WS (1973) Desquamative interstitial pneumonia. Pathological findings and follow-up in 13 patients. Arch Intern Med 132:222–225
Pettavel CA (1911) Über eigentümliche herdförmige Degenerationen der Thyreoidea-Epithelien bei Purpura eines Neonatus. Virchows Arch [Pathol Anat] 206:1–11
Pinkerton H, Smiley WL, Anderson WAD (1945) Giant cell pneumonia with inclusions. A lesion common to Hecht’s disease, distemper and measles. Am J Pathol 21:1–23
Pisano G (1910) Su di un reperto istologico raro in feto scleromatoso. Gazz Osp 31:249–250
Rauh LW, Schmidt R (1965) Measles immunization with killed virus vaccine: serum antibody titers and experience with exposure to measles epidemic. Am J Dis Child 109:232–237
Rector EJ, Rector BS (1934) Intranuclear inclusions in the salivary glands of moles. Am J Pathol 10:629–637
Reynolds EOR (1967) Bronchiolitis. In: Kendig EL (ed) Disorders of the respiratory tract in children. Saunders, Philadelphia
Ribbert H (1904) Ueber protozoenartige Zellen in der Niere eines syphilitischen Neugeborenen und in der Parotis von Kindern. Zentralbl Allg Pathol Pathol Anat 15:945–948
Roberts GBS, Bain AD (1958) The pathology of measles. J Pathol Bacteriol 76:111–118
Roetterink F (in preparation) Epidemiologisch-klinische und pathologisch-anatomische Beobachtungen für Influenzaepidemien mit A2 Hongkong/1/68. Inauguraldissertation, Hannover (and personal communication 1981)
Rowe WP, Huebner RJ, Gilmore LK, Parrott RH, Ward TG (1953) Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc Soc Exp Biol Med 84:570–573
Ruebner BH, Hirano T, Slusser RJ, Medearis DN (1965) Human cytomegalovirus infection. Electron microscopic and histochemical changes in cultures of human fibroblasts. Am J Pathol 46:477–496
Sano T, Niitsu J, Nakagawa J, Ando T (1953) Newborn virus pneumonitis (Type Sendai) I. Report: Clinical observation of a new virus pneumonitis of the newborn. Yokohama Med Bull 4:199–216
Scadding JG (1974) Diffuse pulmonary alveolar fibrosis. Thorax 29:271–281
Scadding JG, Hinson KFW (1967) Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs). Correlation of histology at biopsy with prognosis. Thorax 22:291–403
Schaefer H-E (1998) Ein atypisches Verteilungsmuster der tartratresistenten sauren Phosphatase in Osteoklasten bei Ostitis deformans Paget — zur pathogenetischen und diagnostischen Bedeutung. Verh Dtsch Ges Pathol 64:569
Schaefer H-E (1981) The role of macrophages in storage disease. In: Schmalzl F, Huhn D, Schaefer H-E (eds) Disorders of the monocyte macrophage system. Pathophysiological and clinical aspects. Springer, Berlin Heidelberg New York. (Haematology and blood transfusion, vol 27, pp 121–130)
Schaefer H-E, Müntefering H (1982) Histochemische Untersuchungen zur Abkunft intraalveolarer Zellen bei der desquamativen interstitiellen Pneumonie (Liebow). Ber Pathol 97:215
Schaefer H-E, Hellriegel K-P, Fischer R (1977) Vorkommen tartrat-resistenter saurer Phosphatase in verschiedenen Zelltypen des lymphoretikulären und hämatopoetischen Zellsystems. Blut 34:393–397
Schneweis KE, Käckell MY, Nolte R, Sinapius D, Brandis H (1966a) Respiratorysyncytial-Virus-Infektionen im Kindesalter. Virologische Untersuchungen. Dtsch Med Wochenschr 91:53–55
Schneweis KE, Käckell MY, Nolte R, Sinapius D, Brandis H (1966b) Respiratorysyncytial-Virus-Infektionen im Kindesalter. Klinik und pathologische Anatomie. Dtsch Med Wochenschr 91:153–158
Seifert G, Oehme J (1957) Pathologie und Klinik der Cytomegalie. Thieme, Leipzig
Shedden WJH, Emery JL (1965) Immunofluorescent evidence of respiratory syncytial virus infection in case of giantcell bronchiolitis in children. J Pathol Bacteriol 89:343–347
Sherman FE, Ruckle G (1958) In vivo and in vitro cellular changes specific for measles. Arch Pathol Lab Med 65:587–599
Shope RE (1936) The influenzas of swine and man. The Harvey Lectures, 1935–36, p 183
Shope RE, Francis T (1936) The susceptibility of swine to the virus of human influenza. J Exp Med 64:791–801
Sinigaglia G (1912) Osservazioni sul cimurro. Clin Vet (Milano) 35:421–446
Smith MG (1959) The salivary gland viruses of man and animals (cytomegalic inclusion disease). Prog Med Virol 2:171–202
Sobonya RE, Hiller C, Pingleton W, Watanabe J (1978) Fatal measles (rubeola) pneumonia in adults. Arch Pathol Lab Med 102:366–371
Sohier R, Bensimon P, Lagabrielle B (1957) Infection à adénovirus (type 7 prime) avec atteinte pulmonaire et rénale. Bull Soc Méd Hôp Paris 73:37–42
Sohier R, Chardonnet Y, Prunieras M (1965) Adenoviruses. Status of current knowledge. Prog Med Virol 7:253–325
Spencer H (1973) Pathology of the lung (excluding pulmonary tuberculosis), 2nd edn. Pergamon Press, Oxford
Sperk-Bard E, Kaiserling E, Müller-Hermelink HK (1977) Letale Varizelleninfinektionen. Verh Dtsch Ges Pathol 61:452
Strano AJ (1976) Light microscopy of selected viral diseases (morphology of viral inclusion bodies). Pathol Annu 11:53–75
Straub M, Mulder J (1948) Epithelial lesions in the respiratory tract in human influenzal pneumonia. J Pathol Bacteriol 60:429–434
Taylor-Robinson D, Caunt AE (1972) Varicella virus. Virology monographs. Die Virusforschung in Einzeldarstellungen, Nr. 12. Springer, Wien
Teng CH (1960) Adenovirus pneumonia epidemic among Peking infants and preschool children in 1958. Chin Med J (Engl) 80:331–339
Timbury MC, Edmond E (1979) Herpesviruses. J Clin Pathol 32:859–881
Triebwasser JH, Harris RE, Bryant RE (1967) Varicella pneumonia in adults. Medicine 46:409–423
Tyrrell DAJ, Parsons R (1960) Some virus isolations from common colds. III. Cytopathic effects in tissue cultures. Lancet I:239–242
Vivell OM, Axmann M, Lips G (1962) Die Epidemie von Respirationstrakterkrankungen im Winter 1961/62. Dtsch Med Wochenschr 87:1996–2003
Walsh JJ, Dietlein LF, Low FN, Burch GE, Mogabgab WJ (1961) Bronchotracheal response in human influenza. Type A, Asian strain, as studied by light and electron microscopic examination of bronchoscopic biopsies. Arch Intern Med 108:376–388
Waring JJ, Neubuerger K, Geever EF (1942) Severe forms of chickenpox in adults, with autopsy observations in a case with associated pneumonia and encephalitis. Arch Intern Med 69:384–408
Warthin AS (1931) Occurrence of numerous large giant cells in the tonsils and pharyngeal mucosa in the prodromal stage of measles. Arch Pathol Lab Med 11:864–874
Weinstein L, Meade RH (1956) Respiratory manifestations of chickenpox. Special consideration of features of primary varicella pneumonia. Arch Intern Med 98:91–99
Weller RW (1952) Giant cell pneumonia with inclusions. Pediatrics 10:681–686
Weller TH (1971) The cytomegaloviruses: Ubiquitous agents with protean clinical manifestations. N Engl J Med 285:203–214 (I),
Weller TH (1971) The cytomegaloviruses: Ubiquitous agents with protean clinical manifestations. N Engl J Med 285:267–274 (II)
Wöckel W, Meerbach W (1968) Zur Morphologie der Lunge bei Viruskrankheiten im Säuglings- und Kindesalter. Dtsch Med Wochenschr 93:313–318
Wöckel W, Güthert H, Meerbach W (1963) Zur pathologischen Anatomie der Adenoviruspneumonie. Pathol Microbiol 26:768–788
Wrigth HT, Beckwith JB, Gwinn JL (1964) A fatal case of inclusion body pneumonia in an infant infected with adenovirus type 3. J Pediatr 64:628–633
Yam LT, Li CY, Lam KW (1971) Tartrate-resistant acid phosphatase isoenzyme in the reticulum cells of leukemic reticuloendotheliosis. N Engl J Med 284:357–360
Zakstelskaya LY, Almeida JD, Bradstreet CMP (1967) The morphological characterisation of respiratory syncytial virus by a simple electron microscope technique. Acta Virol (Praha) 11:420–423
Zweerink HJ, Courtneidge SA, Skehel JJ, Crompton MJ, Askonas BA (1977) Cited by Lin Yun Lu et al. (1981) Nature 267:354–356
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Schaefer, HE. (1983). Inflammatory Disease of the Human Lung of Definite or Presumed Viral Origin. Cytologic and Histologic Topics. In: Müller, KM. (eds) Pulmonary Diseases. Current Topics in Pathology, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69134-8_4
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