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Animal Models of Degenerative Joint Disease

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Bone and Joint Disease

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 71))

Abstract

Degenerative joint disease is an extremely common but slowly developing disorder of poorly understood etiology and pathogenesis. Clinically it presents as a heterogeneous population of diseases and usually at an advanced stage. Present therapy is symptomatic, palliative and inadequate, a situation which is clearly unsatisfactory for the physician and the scientist, and especially unfortunate for the patient. As a consequence considerable research effort is needed to clarify the nature of the condition before better therapies can be found. Various clinical, pathological and epidemiological studies have increased our understanding of the clinical features and variants of degenerative joint disease, but many details of the pathogenesis remain obscure.

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Authors
  1. M. E. Adams
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  2. M. E. J. Billingham
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Editors and Affiliations

  1. Department of Morbid Anatomy, The London Hospital Medical College, E1 1BB, GB-London, UK

    C. L. Berry Professor Dr.

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Adams, M.E., Billingham, M.E.J. (1982). Animal Models of Degenerative Joint Disease. In: Berry, C.L. (eds) Bone and Joint Disease. Current Topics in Pathology, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68382-4_9

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  • DOI: https://doi.org/10.1007/978-3-642-68382-4_9

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