Abstract
For many years acute experimental allergic encephalomyelitis (EAE) has been studied as a presumptive model for multiple sclerosis (MS) [1, 2, 13]; more recently, a chronic form of EAE has been described [14, 15]. However, a comparison of MS with either form of EAE has revealed both similarities and differences [9, 10, 13, 15, 20]. Since EAE in animals can be suppressed by the administration of myelin basic protein (MBP) and its derivatives [3, 6, 7, 11, 12, 16, 18], or by synthetic polypeptides [19], an investigation was undertaken to determine the relationship between EAE and MS in this respect by studying the effect of MBP administration in patients with MS.
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© 1980 Springer-Verlag Berlin Heidelberg
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Salk, J., Westall, F.C., Romine, J.S., Wiederholt, W.C. (1980). Studies on Myelin Basic Protein Administration in Multiple Sclerosis Patients. In: Bauer, H.J., Poser, S., Ritter, G. (eds) Progress in Multiple Sclerosis Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67554-6_78
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DOI: https://doi.org/10.1007/978-3-642-67554-6_78
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