Abstract
The concomitant occurrence of (1) a local production of oligoclonal IgG as estimated based on kappa and lambda light polypeptide chain imbalance (KL/LL chain imbalance), and (2) measles and parainfluenza type III (p. infl. type III) specific antibody response in the cerebrospinal fluid (CSF) of many multiple sclerosis (MS) patients prompted an analysis of the correlation between these phenomena [1, 3, 5, 8, 9, 11, 12, 13].
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References
Ammitzbøll T, Clausen J, Fog T (1977) Immunology, histocompatibility and virology in relation to the etiology of multiple sclerosis. Acta Neurol Scand [Suppl 63] 55:99–110
Kerenyi L, Hegedüs K, Palffy G (1975) Characteristic gamma globulin subfractions of native CSF in multiple sclerosis. Brain Res 87:123–125
Link H, Zettervall O (1970) Multiple sclerosis. Disturbed kappa: lambda light chain ratio of immunoglobulin G in cerebrospinal fluid. Clin Exp Immunol 6:435–438
Link H, Müller R (1971) Immunoglobulins in multiple sclerosis and infections of the nervous system. Arch Neurol 25:326–344
Link H, Möller E, Müller R, Norrby E, Olsson JE, Stendahl L, Tibbling G (1977) Immunoglobulin abnormalities in spinal fluid in multiple sclerosis. Acta Neurol Scand [Suppl 63] 55:173–189
Mancini G, Carbonara AO, Heremans JF (1965) Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 2:235–254
McAlpine D, Lumsden CE, Acheson ED (1972) Multiple sclerosis. A reappraisal, 2nd edn. Williams and Wilkins, Baltimore
Norrby E, Vandvik B (1977) The relationship between measles virus specific antibodies and oligoclonal IgG in the cerebrospinal fluid from patients with subacute sclerosing panencephalitis and multiple sclerosis. Acta Neurol Scand [Suppl 63] 55:161–167
Norrby E (1977) Characterization of the virus antibody activity of oligoclonal IgG produced in the central nervous system of patients with multiple sclerosis. In: Ter Meulen V, Katz M (eds) Slow virus infections of the central nervous system. Springer, New York Heidelberg Berlin, pp 159–164
Seidel-Kolodziejowa A (1962) Badania cytologiczne plynu mózgowo-rdzeniowego metodą Sayka. Polski Tygodnik Lekarski 27:1033–1035
Wajgt A, Bogaczynska E (1974) Relationship between parainfluenza type III antibodies and oligoclonal aspect of cerebrospinal fluid immunoglobulin in multiple sclerosis. Ann Immunol (Warszawa-Poznan) 6:27–32
Wajgt A, Bogaczynska E (1974) Studies on the correlation of protein changes in the cerebrospinal fluid and the level of measles antibodies in multiple sclerosis. Neurol Neurochir Pol 8:645–652
Wajgt A, Górny M (1975) Oligoclonal immunoglobulin in the cerebrospinal fluid of patients with sclerosis multiplex. Neurol Neurochir Pol 9:169–177
Weller TH, Coons AH (1954) Fluorescent antibody studies with agent of varicella and herpes zoster propagated “in vitro”. Proc Soc Exp Biol Med 86:789–797
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© 1980 Springer-Verlag Berlin Heidelberg
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Wajgt, A., Bogaczyńska, E. (1980). Oligoclonal Cerebrospinal Fluid Immunoglobulin in Relation to Measles and Parainfluenza Antibody Response in Multiple Sclerosis. In: Bauer, H.J., Poser, S., Ritter, G. (eds) Progress in Multiple Sclerosis Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67554-6_22
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DOI: https://doi.org/10.1007/978-3-642-67554-6_22
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