Abstract
As shown by other investigators with different methods (Binnion, 1973; Chamberlain, 1973a; Coltart et al., 1972; Doherty et al., 1961,1967; Güllner et al., 1974; Redfors et al., 1973), tissue glycoside concentrations of patients on digoxin maintenance therapy are usually markedly higher than “steady-state” serum concentrations. Since the relationship between steady-state serum glycoside concentration and cardiac effect is still controversial, glycoside concentrations were determined in various human tissues in order to analyze the corrélation between serum concentration and tissue concentration.
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Larbig, D., Haasis, R. (1978). Plasma-Tissue Distribution of Different Cardiac Glycosides. In: Bodem, G., Dengler, H.J. (eds) Cardiac Glycosides. International Boehringer Mannheim Symposia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66904-0_11
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DOI: https://doi.org/10.1007/978-3-642-66904-0_11
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