Abstract
For many years, an association has been noted between helminth infection and increased levels of eosinophils in the peripheral blood. In human disease, this association is particularly marked in patients with schistosomiasis, filariasis, ascariasis, trichinosis, and visceral larva migrans; but most helminth infections in which there is a tissue stage of the parasite usually elicit at least some degree of eosinophilia. In addition, the common condition of tropical pulmonary eosinophilia is now believed to be associated with cryptic filarial infections (Neva et al.,1975). High levels of blood eosinophils are also seen in livestock infected with helminths such as Fasciola hepatica, Dictyocaulus viviparus and Oesophagostomum radiatum; while in experimental animals, infection with Trichinella spiralis remains one of the most reliable methods of inducing a peripheral blood eosinophilia.
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Butterworth, A.E. (1977). The Eosinophil and its Role in Immunity to Helminth Infection. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 77. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66740-4_5
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